Phosphoinositide 3-kinase γ regulates airway smooth muscle contraction by modulating calcium oscillations

Journal of Pharmacology and Experimental Therapeutics

Volumn 334, Issue 3, 2010, Pages 703-709

  Jiang, Haihong ^a   Abel, Peter W ^a   Toews, Myron L ^b   Deng, Caishu ^a   Casale, Thomas B ^a   Xie, Yan ^a   Tu, Yaping ^a  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (6 AMINO 9 PURINYLMETHYL) 5 METHYL 3 (2 METHYLPHENYL) 3H QUINAZOLIN 4 ONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 5 (2,2 DIFLUORO BENZO[1,3]DIOXOL 5 YLMETHYLENE)THIAZOLIDINE 2,4 DIONE; 7 METHYL 2 (MORPHOLIN 4 YL) 9 (1 PHENYLAMINOETHYL) PYRIDO[1,2 A] PYRIMIDIN 4 ONE; ACETYLCHOLINE; CALCIUM; PHOSPHATIDYLINOSITOL 3 KINASE ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE BETA; PHOSPHATIDYLINOSITOL 3 KINASE DELTA; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; UNCLASSIFIED DRUG; ENZYME INHIBITOR; ISOENZYME; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PIK3CG PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM MOBILIZATION; CALCIUM SIGNALING; DRUG ACTIVITY; DRUG EFFECT; IC 50; IMMUNOHISTOCHEMISTRY; MOUSE; MUSCLE CONTRACTILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BRONCHUS HYPERREACTIVITY; C57BL MOUSE; CELL SEPARATION; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; FLUORESCENCE MICROSCOPY; IN VITRO STUDY; LUNG; METABOLISM; MUSCLE CONTRACTION; PATHOPHYSIOLOGY; PHYSIOLOGY; RESPIRATORY SYSTEM; TRACHEA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACETYLCHOLINE; ANIMALS; BRONCHIAL HYPERREACTIVITY; CALCIUM SIGNALING; CELL SEPARATION; ENZYME INHIBITORS; IMMUNOHISTOCHEMISTRY; ISOENZYMES; LUNG; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; RESPIRATORY SYSTEM; TRACHEA; CLASS IB PHOSPHATIDYLINOSITOL 3-KINASE; IN VITRO TECHNIQUES; PHOSPHATIDYLINOSITOL 3-KINASES;

EID: 77956236157     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.168518     Document Type: Article

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