Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC 1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase γ and vesicle endocytosis for neuronal survival

Journal of Biological Chemistry

Volumn 285, Issue 13, 2010, Pages 9749-9761

  May, Victor ^a   Lutz, Eve ^b   MacKenzie, Christopher ^b   Schutz, Kristin C ^a   Dozark, Kate ^a   Braas, Karen M ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; AKT ACTIVATION; AKT PHOSPHORYLATION; CELL LINES; CULTURED NEURONS; ENDOCYTIC PATHWAYS; ENDOSOMES; GROWTH FACTOR; IMMUNOPRECIPITATION ANALYSIS; INTEGRATED PROGRAMS; ISOFORMS; NEURONAL SURVIVAL; NEURONAL SYSTEMS; NEUROPROTECTION; NEUROTROPHIC; P38 MAPK; PHOSPHATIDYLINOSITOL 3-KINASE; RECEPTOR ACTIVATION; RECEPTOR SIGNALING; RNA INTERFERENCE; SELECTIVE INHIBITORS; SIGNALING PATHWAYS; TEMPORAL SPECIFICITIES; TRANSACTIVATION; VESICLE ENDOCYTOSIS;

ACTIVATION ANALYSIS; BIOACTIVITY; CELL CULTURE; CELL DEATH; CHEMICAL ACTIVATION; PEPTIDES; PHOSPHORYLATION; RNA; SIGNAL TRANSDUCTION;

SIGNALING;

HORMONE RECEPTOR; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; PROTEIN KINASE B; PROTEIN PAC1HOP1; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR 1; ISOENZYME; ISOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3-KINASE GAMMA;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; ENDOCYTOSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; INTERNALIZATION; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; ANIMAL; ENDOSOME; FEMALE; METABOLISM; PHOSPHORYLATION; SPRAGUE DAWLEY RAT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL SURVIVAL; ENDOCYTOSIS; ENDOSOMES; FEMALE; ISOENZYMES; NEURONS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; PROTEIN ISOFORMS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE, TYPE I; SIGNAL TRANSDUCTION;

EID: 77951223899     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.043117     Document Type: Article

References (88)

1. Sherwood, N. M., Krueckl, S. L., and McRory, J. E. (2000) Endocr. Rev. 21, 619-670
2. Spengler, D., Waeber, C., Pantaloni, C., Holsboer, F., Bockaert, J., Seeburg, P. H., and Journot, L. (1993) Nature 365, 170-175
3. Lutz, E. M., Sheward, W. J., West, K. M., Morrow, J. A., Fink, G., and Harmar, A. J. (1993) FEBS Lett. 334, 3-8
4. Ishihara, T., Shigemoto, R., Mori, K., Takahashi, K., and Nagata, S. (1992) Neuron. 8, 811-819
5. Inagaki, N., Yoshida, H., Mizuta, M., Mizuno, N., Fujii, Y., Gonoi, T., Miyazaki, J.., and Seino, S. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 2679-2683
6. Hosoya, M., Onda, H., Ogi, K., Masuda, Y., Miyamoto, Y., Ohtaki, T., Okazaki, H., Arimura, A., and Fujino, M. (1993) Biochem. Biophys. Res. Commun. 194, 133-143
7. Hashimoto, H., Ishihara, T., Shigemoto, R., Mori, K., and Nagata, S. (1993) Neuron. 11, 333-342
8. Laburthe, M., Couvineau, A., and Marie, J. C. (2002) Receptors Channels 8, 137-153
9. Nicot, A., and DiCicco-Bloom, E. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 4758-4763
10. Villalba, M., Bockaert, J., and Journot, L. (1997) J. Neurosci. 17, 83-90
11. Barrie, A. P., Clohessy, A. M., Buensuceso, C. S., Rogers, M. V., and Allen, J. M. (1997) J. Biol. Chem. 272, 19666-19671
12. McCulloch, D. A., MacKenzie, C. J., Johnson, M. S., Robertson, D. N., Holland, P. J., Ronaldson, E., Lutz, E. M., and Mitchell, R. (2002) Biochem. Soc. Trans. 30, 441-446
13. May, V., and Braas, K. M. (1995) J. Neurochem. 65, 978-987
14. Mustafa, T., Grimaldi, M., and Eiden, L. E. (2007) J. Biol. Chem. 282, 8079-8091
15. Lu, N., Zhou, R., and DiCicco-Bloom, E. (1998) J. Neurosci. Res. 53, 651-662
16. Masuo, Y., Tokito, F., Matsumoto, Y., Shimamoto, N., and Fujino, M. (1994) Neurosci. Lett. 170, 43-46
17. Shuto, Y., Uchida, D., Onda, H., and Arimura, A. (1996) Regul. Pept. 67, 79-83
18. Waschek, J. A., Casillas, R. A., Nguyen, T. B., DiCicco-Bloom, E. M., Carpenter, E. M., and Rodriguez, W. I. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 9602-9607
19. Waschek, J. A. (1996) Ann. N. Y. Acad. Sci. 805, 290-301
20. Carey, R. G., Li, B., and DiCicco-Bloom, E. (2002) J. Neurosci. 22, 1583-1591
21. Lu, N., and DiCicco-Bloom, E. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 3357-3362
22. Basille, M., Gonzalez, B. J., Fournier, A., and Vaudry, H. (1994) Brain Res. Dev. Brain Res. 82, 81-89
23. Vaudry, D., Gonzalez, B. J., Basille, M., Fournier, A., and Vaudry, H. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 9415-9420
24. Lioudyno, M., Skoglösa, Y., Takei, N., and Lindholm, D. (1998) J. Neurosci. Res. 51, 243-256
25. DiCicco-Bloom, E., Deutsch, P. J., Maltzman, J., Zhang, J., Pintar, J. E., Zheng, J., Friedman, W. F., Zhou, X., and Zaremba, T. (2000) Dev. Biol. 219, 197-213
26. Vaudry, D., Gonzalez, B. J., Basille, M., Anouar, Y., Fournier, A., and Vaudry, H. (1998) Neuroscience 84, 801-812
27. Przywara, D. A., Kulkarni, J. S., Wakade, T. D., Leontiev, D. V., and Wakade, A. R. (1998) J. Neurochem. 71, 1889-1897
28. Chang, J. Y., and Korolev, V. V. (1997) Neurochem. Int. 31, 161-167
29. Tabuchi, A., Funaji, K., Nakatsubo, J., Fukuchi, M., Tsuchiya, T., and Tsuda, M. (2003) J. Neurosci. Res. 71, 504-515
30. Kienlen Campard, P., Crochemore, C., René, F., Monnier, D., Koch, B., and Loeffler, J. P. (1997) DNA Cell Biol. 16, 323-333
31. Silveira, M. S., Costa, M. R., Bozza, M., and Linden, R. (2002) J. Biol. Chem. 277, 16075-16080
32. Hansel, D. E., May, V., Eipper, B. A., and Ronnett, G. V. (2001) J. Neurosci. 21, 4625-4636
33. Morio, H., Tatsuno, I., Hirai, A., Tamura, Y., and Saito, Y. (1996) Brain Res. 741, 82-88
34. Arimura, A. (1998) Jpn. J. Physiol. 48, 301-331
35. Ohtaki, H., Nakamachi, T., Dohi, K., Aizawa, Y., Takaki, A., Hodoyama, K., Yofu, S., Hashimoto, H., Shintani, N., Baba, A., Kopf, M., Iwakura, Y., Matsuda, K., Arimura, A., and Shioda, S. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 7488-7493
36. Vaudry, D., Gonzalez, B. J., Basille, M., Yon, L., Fournier, A., and Vaudry, H. (2000) Pharmacol. Rev. 52, 269-324
37. Braas, K. M., and May, V. (1999) J. Biol. Chem. 274, 27702-27710
38. Beaudet, M. M., Parsons, R. L., Braas, K. M., and May, V. (2000) J. Neurosci. 20, 7353-7361
39. Franke, T. F., Kaplan, D. R., and Cantley, L. C. (1997) Cell 88, 435-437
40. Datta, S. R., Brunet, A., and Greenberg, M. E. (1999) Genes Dev. 13, 2905-2927
41. Kaplan, D. R., and Miller, F. D. (2000) Curr. Opin. Neurobiol. 10, 381-391
42. Brunet, A., Datta, S. R., and Greenberg, M. E. (2001) Curr. Opin. Neurobiol. 11, 297-305
43. Brandenburg, C. A., May, V., and Braas, K. M. (1997) J. Neurosci. 17, 4045-4055
44. May, V., Schiller, M. R., Eipper, B. A., and Mains, R. E. (2002) J. Neurosci. 22, 6980-6990
45. Girard, B. M., Keller, E. T., Schutz, K. C., May, V., and Braas, K. M. (2004) Regul. Pept. 123, 107-116
46. May, V., Stoffers, D. A., and Eipper, B. A. (1989) Endocrinology 124, 157-166
47. Lutz, E. M., Ronaldson, E., Shaw, P., Johnson, M. S., Holland, P. J., and Mitchell, R. (2006) Mol. Cell. Neurosci. 31, 193-209
48. Xia, Z., Dickens, M., Raingeaud, J., Davis, R. J., and Greenberg, M. E. (1995) Science 270, 1326-1331
49. Hawes, B. E., Luttrell, L. M., van Biesen, T., and Lefkowitz, R. J. (1996) J. Biol. Chem. 271, 12133-12136
50. Gutkind, J. S. (2000) Sci. STKE 2000, RE1
51. Stork, P. J., and Schmitt, J. M. (2002) Trends Cell Biol. 12, 258-266
52. Wang, Z., Dillon, T. J., Pokala, V., Mishra, S., Labudda, K., Hunter, B., and Stork, P. J. (2006) Mol. Cell. Biol. 26, 2130-2145
53. Choi, E. K., Park, H. J., Ma, J. S., Lee, H. C., Kang, H. C., Kim, B. G., and Kang, I. C. (2004) FEBS Lett. 559, 141-144
54. Mei, F. C., Qiao, J., Tsygankova, O. M., Meinkoth, J. L., Quilliam, L. A., and Cheng, X. (2002) J. Biol. Chem. 277, 11497-11504
55. Davies, S. P., Reddy, H., Caivano, M., and Cohen, P. (2000) Biochem. J. 351, 95-105
56. Camps, M., Rückle, T., Ji, H., Ardissone, V., Rintelen, F., Shaw, J., Ferrandi, C., Chabert, C., Gillieron, C., Françon, B., Martin, T., Gretener, D., Perrin, D., Leroy, D., Vitte, P. A., Hirsch, E., Wymann, M. P., Cirillo, R., Schwarz, M. K., and Rommel, C. (2005) Nat. Med. 11, 936-943
57. Pomel, V., Klicic, J., Covini, D., Church, D. D., Shaw, J. P., Roulin, K., Burgat-Charvillon, F., Valognes, D., Camps, M., Chabert, C., Gillieron, C., Françon, B., Perrin, D., Leroy, D., Gretener, D., Nichols, A., Vitte, P. A., Carboni, S., Rommel, C., Schwarz, M. K., and Rückle, T. (2006) J. Med. Chem. 49, 3857-3871
58. Kerchner, K. R., Clay, R. L., McCleery, G., Watson, N., McIntire, W. E., Myung, C. S., and Garrison, J. C. (2004) J. Biol. Chem. 279, 44554-44562
59. Murga, C., Laguinge, L., Wetzker, R., Cuadrado, A., and Gutkind, J. S. (1998) J. Biol. Chem. 273, 19080-19085
60. Edwards, S. N., and Tolkovsky, A. M. (1994) J. Cell Biol. 124, 537-546
61. May, V., Brandenburg, C. A., and Braas, K. M. (1995) J. Neurosci. 15, 4580-4591
62. Li, M., David, C., Kikuta, T., Somogyvari-Vigh, A., and Arimura, A. (2005) J. Mol. Neurosci. 27, 91-105
63. Kao, S., Jaiswal, R. K., Kolch, W., and Landreth, G. E. (2001) J. Biol. Chem. 276, 18169-18177
64. Hisata, S., Sakisaka, T., Baba, T., Yamada, T., Aoki, K., Matsuda, M., and Takai, Y. (2007) J. Cell Biol. 178, 843-860
65. Liu, C., Takahashi, M., Li, Y., Song, S., Dillon, T. J., Shinde, U., and Stork, P. J. (2008) Mol. Cell. Biol. 28, 7109-7125
66. Stork, P. J. S. (2003) Trends Biochem. Sci. 28, 267-275
67. Vossler, M. R., Yao, H., York, R. D., Pan, M. G., Rim, C. S., and Stork, P. J. (1997) Cell 89, 73-82
68. Bouschet, T., Perez, V., Fernandez, C., Bockaert, J., Eychene, A., and Journot, L. (2003) J. Biol. Chem. 278, 4778-4785
69. Cavanaugh, J. E., Ham, J., Hetman, M., Poser, S., Yan, C., and Xia, Z. (2001) J. Neurosci. 21, 434-443
70. Lopez-Ilasaca, M., Crespo, P., Pellici, P. G., Gutkind, J. S., and Wetzker, R. (1997) Science 275, 394-397
71. Gayer, C. P., Chaturvedi, L. S., Wang, S., Craig, D. H., Flanigan, T., and Basson, M. D. (2009) J. Biol. Chem. 284, 2001-2011
72. Johnson, G. L., and Lapadat, R. (2002) Science 298, 1911-1912
73. Lee, F. S., Rajagopal, R., Kim, A. H., Chang, P. C., and Chao, M. V. (2002) J. Biol. Chem. 277, 9096-9102
74. Rajagopal, R., Chen, Z. Y., Lee, F. S., and Chao, M. V. (2004) J. Neurosci. 24, 6650-6658
75. Johnson-Farley, N. N., Kertesy, S. B., Dubyak, G. R., and Cowen, D. S. (2005) J. Neurochem. 92, 72-82
76. Filippa, N., Sable, C. L., Filloux, C., Hemmings, B., and Van Obberghen, E. (1999) Mol. Cell. Biol. 19, 4989-5000
77. García-Regalado, A., Guzmán-Hernández, M. L., Ramírez-Rangel, I., Robles-Molina, E., Balla, T., Vázquez-Prado, J., and Reyes-Cruz, G. (2008) Mol. Biol. Cell 19, 4188-4200
78. Christoforidis, S., Miaczynska, M., Ashman, K., Wilm, M., Zhao, L., Yip, S. C., Waterfield, M. D., Backer, J. M., and Zerial, M. (1999) Nat. Cell Biol. 1, 249-252
79. Hynes, T. R., Mervine, S. M., Yost, E. A., Sabo, J. L., and Berlot, C. H. (2004) J. Biol. Chem. 279, 44101-44412
80. Macdonald, D. S., Weerapura, M., Beazely, M. A., Martin, L., Czerwinski, W., Roder, J. C., Orser, B. A., and MacDonald, J. F. (2005) J. Neurosci. 25, 11374-11384
81. Ma, Y. C., and Huang, X. Y. (2002) Cell. Mol. Life Sci. 59, 456-462
82. Naga Prasad, S. V., Laporte, S. A., Chamberlain, D., Caron, M. G., Barak, L., and Rockman, H. A. (2002) J. Cell Biol. 158, 563-575
83. Fessart, D., Simaan, M., and Laporte, S. A. (2005) Mol. Endocrinol. 19, 491-503
84. Luttrell, L. M., Ferguson, S. S., Daaka, Y., Miller, W. E., Maudsley, S., Della Rocca, G. J., Lin, F., Kawakatsu, H., Owada, K., Luttrell, D. K., Caron, M. G., and Lefkowitz, R. J. (1999) Science 283, 655-661
85. Waters, C. M., Connell, M. C., Pyne, S., and Pyne, N. J. (2005) Cell. Signal. 17, 263-277
86. Schenck, A., Goto-Silva, L., Collinet, C., Rhinn, M., Giner, A., Habermann, B., Brand, M., and Zerial, M. (2008) Cell 133, 486-497
87. Hunker, C. M., Kruk, I., Hall, J., Giambini, H., Veisaga, M. L., and Barbieri, M. A. (2006) Arch. Biochem. Biophys. 449, 130-142
88. Su, X., Lodhi, I. J., Saltiel, A. R., and Stahl, P. D. (2006) J. Biol. Chem. 281, 27982-27990