-
1
-
-
0021136256
-
The Wisconsin epidemiologic study of diabetic retinopathy: II. prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years
-
Klein R, Klein BE, Moss SE, Davis MD, DeMets DL. The Wisconsin epidemiologic study of diabetic retinopathy: II. prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years. Arch Ophthalmol. 1984;102:520-526.
-
(1984)
Arch Ophthalmol
, vol.102
, pp. 520-526
-
-
Klein, R.1
Klein, B.E.2
Moss, S.E.3
Davis, M.D.4
Demets, D.L.5
-
2
-
-
0037376768
-
A new view of diabetic retinopathy: A neurodegenerative disease of the eye
-
Barber AJ. A new view of diabetic retinopathy: a neurodegenerative disease of the eye. Prog Neuropsychopharmacol Biol Psychiatry. 2003;27:283-290.
-
(2003)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.27
, pp. 283-290
-
-
Barber, A.J.1
-
3
-
-
0030987654
-
Elevated gamma aminobutyric acid, glutamate, and vascular endothelial growth factor levels in the vitreous of patients with proliferative diabetic retinopathy
-
Ambati J, Chalam KV, Chawla DK, et al. Elevated gamma aminobutyric acid, glutamate, and vascular endothelial growth factor levels in the vitreous of patients with proliferative diabetic retinopathy. Arch Ophthalmol. 1997;115:1161-1166.
-
(1997)
Arch Ophthalmol
, vol.115
, pp. 1161-1166
-
-
Ambati, J.1
Chalam, K.V.2
Chawla, D.K.3
-
4
-
-
0030803023
-
Ocular vascular endothelial growth factor levels in diabetic rats are elevated before observable retinal proliferative changes
-
Sone H, Kawakami Y, Okuda Y, et al. Ocular vascular endothelial growth factor levels in diabetic rats are elevated before observable retinal proliferative changes. Diabetologia. 1997;40:726-730.
-
(1997)
Diabetologia
, vol.40
, pp. 726-730
-
-
Sone, H.1
Kawakami, Y.2
Okuda, Y.3
-
5
-
-
15644366961
-
Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoformselective inhibitor
-
Aiello LP, Bursell SE, Clermont A, et al. Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoformselective inhibitor. Diabetes. 1997;46:1473-1480.
-
(1997)
Diabetes
, vol.46
, pp. 1473-1480
-
-
Aiello, L.P.1
Bursell, S.E.2
Clermont, A.3
-
6
-
-
0031000258
-
Vascular dysfunction induced by elevated glucose levels in rats is mediated by vascular endothelial growth factor
-
Tilton RG, Kawamura T, Chang KC, et al. Vascular dysfunction induced by elevated glucose levels in rats is mediated by vascular endothelial growth factor. J Clin Invest. 1997;99:2192-2202.
-
(1997)
J Clin Invest
, vol.99
, pp. 2192-2202
-
-
Tilton, R.G.1
Kawamura, T.2
Chang, K.C.3
-
7
-
-
0029004025
-
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
-
Dvorak HF, Brown LF, Detmar M, Dvorak AM. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol. 1995;146:1029-1039.
-
(1995)
Am J Pathol
, vol.146
, pp. 1029-1039
-
-
Dvorak, H.F.1
Brown, L.F.2
Detmar, M.3
Dvorak, A.M.4
-
8
-
-
33645095226
-
Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease
-
Ng EW, Shima DT, Calias P, Cunningham ET Jr, Guyer DR, Adamis AP. Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease. Nat Rev Drug Discov. 2006;5:123-132.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 123-132
-
-
Ng, E.W.1
Shima, D.T.2
Calias, P.3
Cunningham Jr., E.T.4
Guyer, D.R.5
Adamis, A.P.6
-
9
-
-
9444269815
-
Pharmacotherapy for diabetic retinopathy
-
Comer GM, Ciulla TA. Pharmacotherapy for diabetic retinopathy. Curr Opin Ophthalmol. 2004;15:508-518.
-
(2004)
Curr Opin Ophthalmol
, vol.15
, pp. 508-518
-
-
Comer, G.M.1
Ciulla, T.A.2
-
10
-
-
35548939420
-
The future implications and indications of anti-vascular endothelial growth factor therapy in ophthalmic practice
-
Hussain N, Ghanekar Y, Kaur I. The future implications and indications of anti-vascular endothelial growth factor therapy in ophthalmic practice. Indian J Ophthalmol. 2007;55:445-450.
-
(2007)
Indian J Ophthalmol
, vol.55
, pp. 445-450
-
-
Hussain, N.1
Ghanekar, Y.2
Kaur, I.3
-
11
-
-
0034698943
-
Activation of MAP kinase (ERK-1/ERK-2), tyrosine kinase and VEGF in the human brain following acute ischaemic stroke
-
Slevin M, Krupinski J, Slowik A, Rubio F, Szczudlik A, Gaffney J. Activation of MAP kinase (ERK-1/ERK-2), tyrosine kinase and VEGF in the human brain following acute ischaemic stroke. Neuroreport. 2000;11:2759-2764.
-
(2000)
Neuroreport
, vol.11
, pp. 2759-2764
-
-
Slevin, M.1
Krupinski, J.2
Slowik, A.3
Rubio, F.4
Szczudlik, A.5
Gaffney, J.6
-
12
-
-
33745926802
-
VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis
-
Tam BY, Wei K, Rudge JS, et al. VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis. Nat Med. 2006;12:793-800.
-
(2006)
Nat Med
, vol.12
, pp. 793-800
-
-
Tam, B.Y.1
Wei, K.2
Rudge, J.S.3
-
13
-
-
0034531952
-
MAP Kinases and Hypoxia In the Control of VEGF Expression
-
Berra E, Pages G, Pouysségur J. MAP kinases and hypoxia in the control of VEGF expression. Cancer Metastasis Rev. 2000;19:139-145.
-
(2000)
Cancer Metastasis Rev
, vol.19
, pp. 139-145
-
-
Berra, E.1
Pages, G.2
Pouysségur, J.3
-
14
-
-
28844448789
-
The MAPK-AP-1/-Runx2 signalling axes are implicated in chondrosarcoma pathobiology either independently or via up-regulation of VEGF
-
Papachristou DJ, Papachristou GJ, Papaefthimiou OA, et al. The MAPK-AP-1/-Runx2 signalling axes are implicated in chondrosarcoma pathobiology either independently or via up-regulation of VEGF. Histopathology. 2005;47:565-574.
-
(2005)
Histopathology
, vol.47
, pp. 565-574
-
-
Papachristou, D.J.1
Papachristou, G.J.2
Papaefthimiou, O.A.3
-
15
-
-
0027425113
-
Activation of ternary complex factor Elk-1 by MAP kinases
-
Janknecht R, Ernst WH, Pingoud V, Nordheim A. Activation of ternary complex factor Elk-1 by MAP kinases. EMBO J. 1993;12: 5097-5104.
-
(1993)
EMBO J
, vol.12
, pp. 5097-5104
-
-
Janknecht, R.1
Ernst, W.H.2
Pingoud, V.3
Nordheim, A.4
-
16
-
-
0029032249
-
The regulation of AP-1 activity by mitogen-activated protein kinases
-
Karin M. The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem. 1995;270:16483-16486.
-
(1995)
J Biol Chem
, vol.270
, pp. 16483-16486
-
-
Karin, M.1
-
18
-
-
0030021835
-
The mouse gene for vascular endothelial growth factor: Genomic structure, definition of the transcriptional unit, and characterization of transcriptional and post-transcriptional regulatory sequences
-
Shima DT, Kuroki M, Deutsch U, Ng YS, Adamis AP, D'Amore PA. The mouse gene for vascular endothelial growth factor: genomic structure, definition of the transcriptional unit, and characterization of transcriptional and post-transcriptional regulatory sequences. J Biol Chem. 1996;271:3877-3883.
-
(1996)
J Biol Chem
, vol.271
, pp. 3877-3883
-
-
Shima, D.T.1
Kuroki, M.2
Deutsch, U.3
Ng, Y.S.4
Adamis, A.P.5
D'Amore, P.A.6
-
19
-
-
0025999033
-
The human gene for vascular endothelial growth factor: Multiple protein forms are encoded through alternative exon splicing
-
Tiscerr E, Mitchell R, Hartman T, et al. The human gene for vascular endothelial growth factor: multiple protein forms are encoded through alternative exon splicing. J Biol Chem. 1991;266: 11947-11954.
-
(1991)
J Biol Chem
, vol.266
, pp. 11947-11954
-
-
Tiscerr, E.1
Mitchell, R.2
Hartman, T.3
-
20
-
-
0036289551
-
High glucose induced VEGF expression via PKC and ERK in glomerular podocytes
-
Hoshi S, Nomoto K, Kuromitsu J, Tomari S, Nagata M. High glucose induced VEGF expression via PKC and ERK in glomerular podocytes. Biochem Biophys Res Commun. 2002;290:177-184.
-
(2002)
Biochem Biophys Res Commun
, vol.290
, pp. 177-184
-
-
Hoshi, S.1
Nomoto, K.2
Kuromitsu, J.3
Tomari, S.4
Nagata, M.5
-
21
-
-
0036092794
-
Cyclosporine inhibition of vascular endothelial growth factor production in rheumatoid synovial fibroblasts
-
Cho ML, Cho CS, Min SY, et al. Cyclosporine inhibition of vascular endothelial growth factor production in rheumatoid synovial fibroblasts. Arthritis Rhem. 2002;46:1202-1209.
-
(2002)
Arthritis Rhem
, vol.46
, pp. 1202-1209
-
-
Cho, M.L.1
Cho, C.S.2
Min, S.Y.3
-
22
-
-
0035931493
-
Presenilin-2 (PS2) expression upregulation in a model of retinopathy of prematurity and pathoangiogenesis
-
Lukiw WJ, Gordon WC, Rogaev EI, Thompson H, Bazan NG. Presenilin-2 (PS2) expression upregulation in a model of retinopathy of prematurity and pathoangiogenesis. Neuroreport. 2001;12: 53-57.
-
(2001)
Neuroreport
, vol.12
, pp. 53-57
-
-
Lukiw, W.J.1
Gordon, W.C.2
Rogaev, E.I.3
Thompson, H.4
Bazan, N.G.5
-
23
-
-
33748700615
-
A comparison of quantitative-competitive and realtime PCR assays using an identical target sequence to detect Epstein-Barr virus viral load in the peripheral blood
-
Xu S, Green M, Kingsley L, Webber S, Rowe D. A comparison of quantitative-competitive and realtime PCR assays using an identical target sequence to detect Epstein-Barr virus viral load in the peripheral blood. J Virol Methods. 2006;137:205-212.
-
(2006)
J Virol Methods
, vol.137
, pp. 205-212
-
-
Xu, S.1
Green, M.2
Kingsley, L.3
Webber, S.4
Rowe, D.5
-
24
-
-
59049096630
-
Positive correlation between relative mRNA expression of PRNP and SPRN in cerebral and cerebellar cortex of sheep
-
Lampo E, Van Poucke M, Vandesompele J, Erkens T, Van Zeveren A, Peelman LJ. Positive correlation between relative mRNA expression of PRNP and SPRN in cerebral and cerebellar cortex of sheep. Mol Cell Probes. 2009;23:60-64.
-
(2009)
Mol Cell Probes
, vol.23
, pp. 60-64
-
-
Lampo, E.1
van Poucke, M.2
Vandesompele, J.3
Erkens, T.4
van Zeveren, A.5
Peelman, L.J.6
-
25
-
-
33750277449
-
Development of a new set of reference genes for normalization of realtime RT-PCR data of porcine backfat and longissimus dorsi muscle, and evaluation with PPARGC1A
-
Erkens T, Van Poucke M, Vandesompele J, Goossens K, Van Zeveren A, Peelman LJ. Development of a new set of reference genes for normalization of realtime RT-PCR data of porcine backfat and longissimus dorsi muscle, and evaluation with PPARGC1A. BMC Biotechnol. 2006;6:41.
-
(2006)
BMC Biotechnol
, vol.6
, pp. 41
-
-
Erkens, T.1
van Poucke, M.2
Vandesompele, J.3
Goossens, K.4
van Zeveren, A.5
Peelman, L.J.6
-
26
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 2001;25:402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
27
-
-
0031900740
-
Signal transduction through MAP kinase cascades
-
Lewis TS, Shapiro PS, Ahn NG. Signal transduction through MAP kinase cascades. Adv Cancer Res. 1998;74:49-139.
-
(1998)
Adv Cancer Res
, vol.74
, pp. 49-139
-
-
Lewis, T.S.1
Shapiro, P.S.2
Ahn, N.G.3
-
28
-
-
34548623314
-
Emerging role of mitogen-activated protein kinases in peripheral neuropathies
-
Cavaletti G, Miloso M, Nicolini G, Scuteri A, Tredici G. Emerging role of mitogen-activated protein kinases in peripheral neuropathies. J Peripher Nerv Syst. 2007;12:175-194.
-
(2007)
J Peripher Nerv Syst
, vol.12
, pp. 175-194
-
-
Cavaletti, G.1
Miloso, M.2
Nicolini, G.3
Scuteri, A.4
Tredici, G.5
-
29
-
-
0031596327
-
Alpha2-adrenergic agonists selectively activate extracellular signal-regulated kinases in Müller cells in vivo
-
Peng M, Li Y, Luo Z, Liu C, Laties AM, Wen R. Alpha2-adrenergic agonists selectively activate extracellular signal-regulated kinases in Müller cells in vivo. Invest Ophthalmol Vis Sci. 1998;39:1721-1726.
-
(1998)
Invest Ophthalmol Vis Sci
, vol.39
, pp. 1721-1726
-
-
Peng, M.1
Li, Y.2
Luo, Z.3
Liu, C.4
Laties, A.M.5
Wen, R.6
-
30
-
-
0034644538
-
Translocation and reversible localization of signaling proteins: A dynamic future for signal transduction
-
Teruel MN, Meyer T. Translocation and reversible localization of signaling proteins: a dynamic future for signal transduction. Cell. 2000;103:181-184.
-
(2000)
Cell
, vol.103
, pp. 181-184
-
-
Teruel, M.N.1
Meyer, T.2
-
31
-
-
0035859030
-
The ins and outs of signaling
-
Downward J. The ins and outs of signaling. Nature. 2001;411: 759-762.
-
(2001)
Nature
, vol.411
, pp. 759-762
-
-
Downward, J.1
-
32
-
-
1542398801
-
Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis
-
Giuliani N, Lunghi P, Morandi F, et al. Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis. Leukemia. 2004;18: 628-635.
-
(2004)
Leukemia
, vol.18
, pp. 628-635
-
-
Giuliani, N.1
Lunghi, P.2
Morandi, F.3
-
33
-
-
0037090221
-
Reactive oxygen species accelerate production of vascular endothelial growth factor by advanced glycation end products in RAW264.7 mouse macrophages
-
Urata Y, Yamaguchi M, Higashiyama Y, et al. Reactive oxygen species accelerate production of vascular endothelial growth factor by advanced glycation end products in RAW264.7 mouse macrophages. Free Radic Biol Med. 2002;32:688-701.
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 688-701
-
-
Urata, Y.1
Yamaguchi, M.2
Higashiyama, Y.3
-
34
-
-
41149155362
-
Cellular signaling and potential new treatment targets in diabetic retinopathy (review)
-
Khan ZA, Chakrabarti S. Cellular signaling and potential new treatment targets in diabetic retinopathy (review). Exp Diabetes Res. 2007;2007:31867.
-
(2007)
Exp Diabetes Res
, vol.2007
, pp. 31867
-
-
Khan, Z.A.1
Chakrabarti, S.2
-
35
-
-
34447096817
-
Ascofuranone suppresses PMAmediated matrix metalloproteinase-9 gene activation through the Ras/Raf/MEK/ERK-and Ap1-dependent mechanisms
-
Cho HJ, Kang JH, Kwak JY, et al. Ascofuranone suppresses PMAmediated matrix metalloproteinase-9 gene activation through the Ras/Raf/MEK/ERK-and Ap1-dependent mechanisms. Carcinogenesis. 2007;28:1104-1110.
-
(2007)
Carcinogenesis
, vol.28
, pp. 1104-1110
-
-
Cho, H.J.1
Kang, J.H.2
Kwak, J.Y.3
-
36
-
-
0037192802
-
Acidic extracellular pH induces vascular endothelial growth factor (VEGF) in human glioblastoma cells via ERK1/2 MAPK signalling pathway
-
Xu L, Fukumura D, Jain RK. Acidic extracellular pH induces vascular endothelial growth factor (VEGF) in human glioblastoma cells via ERK1/2 MAPK signalling pathway. J Biol Chem. 2002;277: 11368-11374.
-
(2002)
J Biol Chem
, vol.277
, pp. 11368-11374
-
-
Xu, L.1
Fukumura, D.2
Jain, R.K.3
-
37
-
-
6044277953
-
Human Bcl-2 activates ERK signaling pathway to regulate activating protein-1, lens epitheliumderived growth factor and downstream genes
-
Feng H, Xiang H, Mao Y-M, et al. Human Bcl-2 activates ERK signaling pathway to regulate activating protein-1, lens epitheliumderived growth factor and downstream genes. Oncogene. 2004; 23:7310-7321.
-
(2004)
Oncogene
, vol.23
, pp. 7310-7321
-
-
Feng, H.1
Xiang, H.2
Mao, Y.-M.3
-
38
-
-
0036183640
-
The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxiainducible factor 1 in response to hypoxia
-
Salnikow K, Kluz T, Costa M, et al. The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxiainducible factor 1 in response to hypoxia. Mol Cell Biol. 2002;22: 1734-1741.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 1734-1741
-
-
Salnikow, K.1
Kluz, T.2
Costa, M.3
|