Smad3 regulates Rho signaling via NET1 in the transforming growth factor-β-induced epithelial-mesenchymal transition of human retinal pigment epithelial cells

Journal of Biological Chemistry

Volumn 285, Issue 34, 2010, Pages 26618-26627

  Lee, Jungeun ^a   Moon, Hyun Jeong ^a   Lee, Jong Min ^a   Joo, Choun Ki ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CONSTITUTIVELY ACTIVES; CYTOPLASMIC LOCALIZATION; CYTOSKELETAL; EPITHELIAL-MESENCHYMAL TRANSITION; GTPASE ACTIVITY; GUANINE NUCLEOTIDE EXCHANGE FACTORS; INDUCED STRESS; N-CADHERIN; PROTEIN EXPRESSIONS; RETINAL PIGMENT EPITHELIAL CELLS; SMAD SIGNALING; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTORS;

CELL CULTURE; CELLS; GENETIC ENGINEERING; OPHTHALMOLOGY; PEPTIDES; SIGNALING; TRANSPLANTATION (SURGICAL);

ALDEHYDES;

ACTIN; CADHERIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MESSENGER RNA; PROTEIN NET1; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVITY; ENZYME REGULATION; EPITHELIUM; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; MESENCHYME; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

CELL LINE; CYTOSKELETON; EPITHELIAL CELLS; HUMANS; MESENCHYMAL STEM CELLS; ONCOGENE PROTEINS; RETINAL PIGMENT EPITHELIUM; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 77956199210     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.073155     Document Type: Article

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