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Volumn 17, Issue 14, 1998, Pages 4075-4085

Activation of RhoA and SAPK/JNK signalling pathways by the RhoA-specific exchange factor mNET1

Author keywords

Cdc42; mNET1; Rac1; RhoA; SRF

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; PLECKSTRIN; RHO FACTOR; TRANSCRIPTION FACTOR;

EID: 0032527805     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.14.4075     Document Type: Article
Times cited : (97)

References (47)
  • 1
    • 0027727654 scopus 로고
    • Rapid transe optional assay for the expression of two distinct reporter genes by microinjection
    • Alberts,A.S., Frost,J.A. and Thorburn,A.M. (1993) Rapid transe optional assay for the expression of two distinct reporter genes by microinjection. DNA Cell Biol., 12, 935-943.
    • (1993) DNA Cell Biol. , vol.12 , pp. 935-943
    • Alberts, A.S.1    Frost, J.A.2    Thorburn, A.M.3
  • 2
    • 0032549013 scopus 로고    scopus 로고
    • Activation of SRF-regulated chromosomal templates by Rho-family GTPases requires a signal that also induces H4 hyperacetylation
    • Alberts,A., Geneste,O. and Treisman,R. (1998a) Activation of SRF-regulated chromosomal templates by Rho-family GTPases requires a signal that also induces H4 hyperacetylation. Cell, 92, 475-487.
    • (1998) Cell , vol.92 , pp. 475-487
    • Alberts, A.1    Geneste, O.2    Treisman, R.3
  • 3
    • 0032502680 scopus 로고    scopus 로고
    • Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7
    • Alberts,A.S., Bouquin,N., Johnston,L.H. and Treisman,R.H. (1998b) Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7. J. Biol. Chem., 273, 8616-8622.
    • (1998) J. Biol. Chem. , vol.273 , pp. 8616-8622
    • Alberts, A.S.1    Bouquin, N.2    Johnston, L.H.3    Treisman, R.H.4
  • 4
    • 0032579405 scopus 로고    scopus 로고
    • Constitutive activation of c-Jun N-terminal kinase by a mutant epidermal growth factor receptor
    • Antonyak,M.A., Moscatello,D.K. and Wong,A.J. (1998) Constitutive activation of c-Jun N-terminal kinase by a mutant epidermal growth factor receptor. J. Biol. Chem., 273, 2817-2822.
    • (1998) J. Biol. Chem. , vol.273 , pp. 2817-2822
    • Antonyak, M.A.1    Moscatello, D.K.2    Wong, A.J.3
  • 6
    • 0029917989 scopus 로고    scopus 로고
    • Isolation of a novel oncogene, NET1, from neuroepithelioma cells by expression cDNA cloning
    • Chan,A.M., Takai,S., Yamada,K. and Miki,J. (1996) Isolation of a novel oncogene, NET1, from neuroepithelioma cells by expression cDNA cloning. Oncogene, 12, 1259-1266.
    • (1996) Oncogene , vol.12 , pp. 1259-1266
    • Chan, A.M.1    Takai, S.2    Yamada, K.3    Miki, J.4
  • 7
    • 0031036224 scopus 로고    scopus 로고
    • P120 GAP modulates Ras activation of Jun kinases and transformation
    • Clark,G.J., Westwick,J.K. and Der,C.J. (1997) p120 GAP modulates Ras activation of Jun kinases and transformation. J. Biol. Chem., 272, 1677-1681.
    • (1997) J. Biol. Chem. , vol.272 , pp. 1677-1681
    • Clark, G.J.1    Westwick, J.K.2    Der, C.J.3
  • 8
    • 0029055812 scopus 로고
    • The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
    • Coso,O.A., Chiariello,M., Yu,J.C., Teramoto,H., Crespo,P., Xu,N., Miki,T. and Gutkind,J.S. (1995) The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 81, 1137-1146.
    • (1995) Cell , vol.81 , pp. 1137-1146
    • Coso, O.A.1    Chiariello, M.2    Yu, J.C.3    Teramoto, H.4    Crespo, P.5    Xu, N.6    Miki, T.7    Gutkind, J.S.8
  • 9
    • 0029952315 scopus 로고    scopus 로고
    • The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains
    • Debant,A., Serra-Pages,C., Seipel,K., O'Brien,S., Tang,M. and Park,S.H. (1996) The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains. Proc. Natl Acad. Sci. USA, 93, 5466-5471.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 5466-5471
    • Debant, A.1    Serra-Pages, C.2    Seipel, K.3    O'Brien, S.4    Tang, M.5    Park, S.H.6
  • 10
    • 0023715225 scopus 로고
    • Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP
    • Feig,L.A. and Cooper,G.M. (1988) Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP. Mol. Cell. Biol., 8, 3235-3243.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3235-3243
    • Feig, L.A.1    Cooper, G.M.2
  • 11
    • 0023084055 scopus 로고
    • Progressive sequence alignment as a prerequisite to correct phylogenetic trees
    • Feng,D.F. and Doolittle,R.F. (1987) Progressive sequence alignment as a prerequisite to correct phylogenetic trees. J. Mol. Evol., 25, 351-360.
    • (1987) J. Mol. Evol. , vol.25 , pp. 351-360
    • Feng, D.F.1    Doolittle, R.F.2
  • 12
    • 0029973601 scopus 로고    scopus 로고
    • Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein
    • Glaven,J.A., Whitehead,I.P., Nomanbhoy,T., Kay,R. and Cerione,R.A. (1996) Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein. J. Biol. Chem., 271, 27374-27381.
    • (1996) J. Biol. Chem. , vol.271 , pp. 27374-27381
    • Glaven, J.A.1    Whitehead, I.P.2    Nomanbhoy, T.3    Kay, R.4    Cerione, R.A.5
  • 13
    • 0027958423 scopus 로고
    • Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product
    • Hart,M.J., Eva,A., Zangrilli,D., Aaronson,S.A., Evans,T., Cerione,R.A. and Zheng,Y. (1994) Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product. J. Biol. Chem., 269, 62-65.
    • (1994) J. Biol. Chem. , vol.269 , pp. 62-65
    • Hart, M.J.1    Eva, A.2    Zangrilli, D.3    Aaronson, S.A.4    Evans, T.5    Cerione, R.A.6    Zheng, Y.7
  • 14
    • 0029015774 scopus 로고
    • The Rho family GTPases RhoA, Rac1 and CDC42Hs regulate transcriptional activation by SRF
    • Hill,C.S., Wynne,J., and Treisman,R. (1995) The Rho family GTPases RhoA, Rac1 and CDC42Hs regulate transcriptional activation by SRF. Cell, 81, 1159-1170.
    • (1995) Cell , vol.81 , pp. 1159-1170
    • Hill, C.S.1    Wynne, J.2    Treisman, R.3
  • 15
    • 0028110120 scopus 로고
    • A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways
    • Horii,Y., Beeler,J.F., Sakaguchi,K., Tachibana,M. and Miki,T. (1994) A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways. EMBO J., 13, 4776-4786.
    • (1994) EMBO J. , vol.13 , pp. 4776-4786
    • Horii, Y.1    Beeler, J.F.2    Sakaguchi, K.3    Tachibana, M.4    Miki, T.5
  • 16
    • 0028800305 scopus 로고
    • Activation of Rac1, RhoA and mitogen-activated protein kinases is required for Ras transformation
    • Khosravi-Far,R., Solski,P.A., Clark,G.J., Kinch,M.S. and Der,C.J. (1995) Activation of Rac1, RhoA and mitogen-activated protein kinases is required for Ras transformation. Mol. Cell. Biol., 15, 6443-6453.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6443-6453
    • Khosravi-Far, R.1    Solski, P.A.2    Clark, G.J.3    Kinch, M.S.4    Der, C.J.5
  • 17
    • 0030910236 scopus 로고    scopus 로고
    • Prenylation of RhoB is required for its cell transforming function but not its ability to activate serum response element-dependent transcription
    • Lebowitz,P.F., Du,W. and Prendergast,G.C. (1997) Prenylation of RhoB is required for its cell transforming function but not its ability to activate serum response element-dependent transcription. J. Biol. Chem., 272, 16093-16095.
    • (1997) J. Biol. Chem. , vol.272 , pp. 16093-16095
    • Lebowitz, P.F.1    Du, W.2    Prendergast, G.C.3
  • 18
    • 0029805324 scopus 로고    scopus 로고
    • Regulation of phosphorylation pathways by p21 GTPases. the p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways
    • Lim,L., Manser,E., Leung,T. and Hall,C. (1996) Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways. Eur. J. Biochem., 242, 171-185.
    • (1996) Eur. J. Biochem. , vol.242 , pp. 171-185
    • Lim, L.1    Manser, E.2    Leung, T.3    Hall, C.4
  • 19
    • 0031260578 scopus 로고    scopus 로고
    • A novel Cdc42Hs mutant induces cellular transformation
    • Lin,R., Bagrodia,S., Cerione,R. and Manor,D. (1997) A novel Cdc42Hs mutant induces cellular transformation. Curr. Biol., 7, 794-797.
    • (1997) Curr. Biol. , vol.7 , pp. 794-797
    • Lin, R.1    Bagrodia, S.2    Cerione, R.3    Manor, D.4
  • 20
    • 0029070887 scopus 로고
    • Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs
    • Minden,A., Lin,A., Claret,F.X., Abo,A. and Karin,M. (1995) Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell, 81, 1147-1157.
    • (1995) Cell , vol.81 , pp. 1147-1157
    • Minden, A.1    Lin, A.2    Claret, F.X.3    Abo, A.4    Karin, M.5
  • 21
    • 0023300801 scopus 로고
    • Xenopus cytoskeletal actin and human c-fos gene promoters share a conserved protein-binding site
    • Mohun,T., Garrett,N. and Treisman,R. (1987) Xenopus cytoskeletal actin and human c-fos gene promoters share a conserved protein-binding site. EMBO J., 6, 667-673.
    • (1987) EMBO J. , vol.6 , pp. 667-673
    • Mohun, T.1    Garrett, N.2    Treisman, R.3
  • 23
    • 0029101360 scopus 로고
    • An essential role for Rho, Rac and Cdc42 GTPases in cell cycle progression through G1
    • Olson,M.R. Ashworth,A. and Hall,A. (1995) An essential role for Rho, Rac and Cdc42 GTPases in cell cycle progression through G1. Science, 269, 1270-1272.
    • (1995) Science , vol.269 , pp. 1270-1272
    • Olson, M.R.1    Ashworth, A.2    Hall, A.3
  • 24
    • 0030466893 scopus 로고    scopus 로고
    • Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases
    • Olson,M.F., Pasteris,N.G., Gorski,J.L. and Hall,A. (1996) Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases. Curr. Biol., 6, 1628-1633.
    • (1996) Curr. Biol. , vol.6 , pp. 1628-1633
    • Olson, M.F.1    Pasteris, N.G.2    Gorski, J.L.3    Hall, A.4
  • 28
    • 0029005240 scopus 로고
    • Comparative analysis of the ternary complex factors Elk-1, SAP-1a and SAP-2 (ERP/NET)
    • Price,M.A., Rogers,A.E. and Treisman,R. (1995) Comparative analysis of the ternary complex factors Elk-1, SAP-1a and SAP-2 (ERP/NET). EMBO J., 14, 2589-2601.
    • (1995) EMBO J. , vol.14 , pp. 2589-2601
    • Price, M.A.1    Rogers, A.E.2    Treisman, R.3
  • 29
    • 0028903247 scopus 로고
    • An essential role for rac in ras transformation
    • Qiu,R.G., Chen,J., Kirn,D., McCormick,F. and Symons,M. (1995a) An essential role for rac in ras transformation. Nature, 374, 457-459.
    • (1995) Nature , vol.374 , pp. 457-459
    • Qiu, R.G.1    Chen, J.2    Kirn, D.3    McCormick, F.4    Symons, M.5
  • 31
    • 0030992814 scopus 로고    scopus 로고
    • Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation
    • Qiu,R.G., Abo,A., McCormick,F. and Symons,M. (1997) Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation. Mol. Cell. Biol., 17, 3449-3458.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3449-3458
    • Qiu, R.G.1    Abo, A.2    McCormick, F.3    Symons, M.4
  • 32
    • 0026654125 scopus 로고
    • The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
    • Ridley,A.J., Paterson,H.F., Johnston,C.L., Diekmann,D. and Hall,A. (1992) The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell, 70, 401-410.
    • (1992) Cell , vol.70 , pp. 401-410
    • Ridley, A.J.1    Paterson, H.F.2    Johnston, C.L.3    Diekmann, D.4    Hall, A.5
  • 33
    • 0030927326 scopus 로고    scopus 로고
    • Activation of the JNK pathway is essential for transformation by the Met oncogene
    • Rodrigues,G.A., Park,M. and Schlessinger,J. (1997) Activation of the JNK pathway is essential for transformation by the Met oncogene. EMBO J., 16, 2634-2645.
    • (1997) EMBO J. , vol.16 , pp. 2634-2645
    • Rodrigues, G.A.1    Park, M.2    Schlessinger, J.3
  • 34
    • 0032473351 scopus 로고    scopus 로고
    • RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation
    • Sahai,E., Alberts,A.S. and Treisman,R. (1998) RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation. EMBO J., 17, 1350-1361.
    • (1998) EMBO J. , vol.17 , pp. 1350-1361
    • Sahai, E.1    Alberts, A.S.2    Treisman, R.3
  • 36
    • 0029911520 scopus 로고    scopus 로고
    • The small GTP-binding protein rho activates c-Jun N-terminal kinases/stress-activated protein kinases in human kidney 293T cells. Evidence for a PAK-independent signaling pathway
    • Teramoto,H., Crespo,P., Coso,O.A., Igishi,T., Xu,N. and Gutkind,J.-S. (1996) The small GTP-binding protein rho activates c-Jun N-terminal kinases/stress-activated protein kinases in human kidney 293T cells. Evidence for a PAK-independent signaling pathway. J. Biol. Chem., 271, 25731-25734.
    • (1996) J. Biol. Chem. , vol.271 , pp. 25731-25734
    • Teramoto, H.1    Crespo, P.2    Coso, O.A.3    Igishi, T.4    Xu, N.5    Gutkind, J.-S.6
  • 37
    • 0027972531 scopus 로고
    • Novel human oncogene lbc detected by transfection with distinct homology regions to signal transduction products
    • Toksoz,D. and Williams,D.A. (1994) Novel human oncogene lbc detected by transfection with distinct homology regions to signal transduction products. Oncogene, 9, 621-628.
    • (1994) Oncogene , vol.9 , pp. 621-628
    • Toksoz, D.1    Williams, D.A.2
  • 38
    • 0030968580 scopus 로고    scopus 로고
    • Rho GTPases and signaling networks
    • Van Aelst,L. and D'Souza-Schorey,C. (1997) Rho GTPases and signaling networks. Genes Dev., 11, 2295-2322.
    • (1997) Genes Dev. , vol.11 , pp. 2295-2322
    • Van Aelst, L.1    D'Souza-Schorey, C.2
  • 40
    • 0028948329 scopus 로고
    • Retroviral transduction and oncogenic selection of a cDNA encoding Dbs, a homolog of the Dbl guanine nucleotide exchange factor
    • Whitehead,I., Kirk,H. and Kay,R. (1995a) Retroviral transduction and oncogenic selection of a cDNA encoding Dbs, a homolog of the Dbl guanine nucleotide exchange factor. Oncogene, 10, 713-721.
    • (1995) Oncogene , vol.10 , pp. 713-721
    • Whitehead, I.1    Kirk, H.2    Kay, R.3
  • 41
    • 0029155976 scopus 로고
    • Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C
    • Whitehead,I., Kirk,H., Tognon,C., Trigo-Gonzalez,G. and Kay,R. (1995b) Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C. J. Biol. Chem., 271, 18388-18395.
    • (1995) J. Biol. Chem. , vol.271 , pp. 18388-18395
    • Whitehead, I.1    Kirk, H.2    Tognon, C.3    Trigo-Gonzalez, G.4    Kay, R.5
  • 42
    • 0029784842 scopus 로고    scopus 로고
    • Expression cloning of lsc, a novel oncogene with structural similarities to the Dbl family of guanine nucleotide exchange factors
    • Whitehead,I.P., Khosravi Far,R., Kirk,H., Trigo Gonzalez,G., Der,C.J. and Kay,R. (1996) Expression cloning of lsc, a novel oncogene with structural similarities to the Dbl family of guanine nucleotide exchange factors. J. Biol. Chem., 271, 18643-18650.
    • (1996) J. Biol. Chem. , vol.271 , pp. 18643-18650
    • Whitehead, I.P.1    Khosravi Far, R.2    Kirk, H.3    Trigo Gonzalez, G.4    Der, C.J.5    Kay, R.6
  • 44
    • 0028820587 scopus 로고
    • Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator PAK1
    • Zhang,S., Han,J., Sells,M.A., Chernoff,J., Knaus,U.G., Ulevitch,R.J. and Bokoch,G.M. (1995) Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator PAK1. J. Biol. Chem., 270, 23934-23936.
    • (1995) J. Biol. Chem. , vol.270 , pp. 23934-23936
    • Zhang, S.1    Han, J.2    Sells, M.A.3    Chernoff, J.4    Knaus, U.G.5    Ulevitch, R.J.6    Bokoch, G.M.7
  • 45
    • 0028955710 scopus 로고
    • Interactions among proteins involved in bud-site selection and bud-site assembly in Saccharomyces cerevisiae
    • Zheng,Y., Bender,A. and Cerione,R.A. (1995a) Interactions among proteins involved in bud-site selection and bud-site assembly in Saccharomyces cerevisiae. J. Biol. Chem., 270, 626-630.
    • (1995) J. Biol. Chem. , vol.270 , pp. 626-630
    • Zheng, Y.1    Bender, A.2    Cerione, R.A.3
  • 46
    • 0029166210 scopus 로고
    • Guanine nucleotide exchange catalyzed by dbl oncogene product
    • Zheng,Y., Hart,M.J. and Cerione,R.A. (1995b) Guanine nucleotide exchange catalyzed by dbl oncogene product. Methods Enzymol., 256, 77-84.
    • (1995) Methods Enzymol. , vol.256 , pp. 77-84
    • Zheng, Y.1    Hart, M.J.2    Cerione, R.A.3
  • 47
    • 0028967665 scopus 로고
    • Direct involvement of the small GTP-binding protein Rho in lbc oncogene function
    • Zhengx Olson,M.F., Hall,A., Cerione,R.A. and Toksoz,D. (1995c) Direct involvement of the small GTP-binding protein Rho in lbc oncogene function. J. Biol. Chem., 270, 9031-9034.
    • (1995) J. Biol. Chem. , vol.270 , pp. 9031-9034
    • Zhengx Olson, M.F.1    Hall, A.2    Cerione, R.A.3    Toksoz, D.4


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