Epithelial-mesenchymal transition in proliferative vitreoretinopathy: Intermediate filament protein expression in retinal pigment epithelial cells

Investigative Ophthalmology and Visual Science

Volumn 40, Issue 9, 1999, Pages 2062-2072

  Casaroli Marano, Ricardo Pedro ^a   Pagan, Roser ^a   Vilaró, Senén ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERMEDIATE FILAMENT PROTEIN; VIMENTIN;

ARTICLE; CELL SHAPE; CELL TYPE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; MESENCHYME; PHENOTYPE; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; VITREORETINOPATHY;

ADULT; AGED; AGED, 80 AND OVER; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELLS, CULTURED; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EPIRETINAL MEMBRANE; EPITHELIOID CELLS; FIBROBLASTS; HUMANS; IMMUNOPHENOTYPING; INTERMEDIATE FILAMENT PROTEINS; MICROSCOPY, IMMUNOELECTRON; MIDDLE AGED; PIGMENT EPITHELIUM OF EYE; VITREORETINOPATHY, PROLIFERATIVE;

EID: 0032841562     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Kampik A, Kenyon KR, Michels RG, et al. Epiretinal and vitreous membranes: comparative study of 56 cases. Arch Ophthalmol. 1981;99:1445-1454.
2. Laqua H, Machemer R. Glial cell proliferation in retinal detachment (massive periretinal proliferation). Am J Ophthalmol. 1975;80: 602-618.
3. Clarkson JG, Green WR, Massof D. A histopathological review of 168 cases of preretinal membrane. Am J Ophthalmol. 1977;84:1-17.
4. Wiedemann P, Heimann K. Proliferative vitreoretinopathy. Curr Opin Ophthalmol. 1992;3:357-365.
5. Nagasaki H, Shinagawa K. Risk factors for proliferative vitreoretinopathy. Curr Opin Ophthalmol. 1995;6:70-75.
6. Pastor JC. Proliferative vitreoretinopathy: an overview. Surv Ophthalmol. 1998;43:3-18.
7. Machemer R, Van Horn D, Aaberg TM. Pigment epithelial proliferation in human retinal detachment with massive periretinal proliferation. Am J Ophthalmol. 1978;85:181-191.
8. Wallow IHL, Miller SA. Preretinal membranes by retinal pigment epithelium. Arch Ophthalmol. 1978;96:1643-1646.
9. Lindsey PS, Michels RG, Luckenbach M, et al. Ultrastructure of epiretinal membrane causing retinal starfold. Ophthalmology. 1983;90:578-583.
10. Yamamoto T, Yamashita H, Hori S. Electron microscopic observation of preretinal membranes. Jpn J Ophthalmol. 1989;33:151-156.
11. Hiscott PS, Grierson I, McLeod D. Natural history of fibrocellular epiretinal membranes: a quantitative, auturadiographic, and immunohistochemical study. Br J Ophthalmol. 1985;69:810-823.
12. Shirakawa H, Yoshimura N, Yamakawa R, et al. Cell components in proliferative vitreoretinopathy: immunofluorescent double staining of cultured cells from proliferative tissues. Ophthalmologica. 1987;194:56-62.
13. Morino I, Hiscott P, McKechnie N, et al. Variation in epiretinal membrane components with clinical duration of proliferative tissue. Br J Ophthalmol. 1990;74:393-399.
14. Vidaurri-Leal J, Hohman R, Glaser BM. Effect of vitreous on morphologic characteristics of retinal pigment epithelial cells: a new approach to the study of proliferative vitreoretinopathy. Arch Ophthalmol. 1984;102:1220-1223.
15. Greenburg G, Hay ED. Epithelia suspended in collagen gels can lose polarity and express characteristics of migrating mesenchymal cells. J Cell Biol. 1982;95:333-339.
16. Vinores SA, Campochiaro PA, McGehee R, et al. Ultrastructural and immunocytochemical changes in retinal pigment epithelium, retinal glia, and fibroblast in vitreous culture. Invest Ophthalmol Vis Sci. 1990;31:2529-2549.
17. Campochiaro PA, Jerdan JA, Glaser BM. Serum contains chemoattractants for human retinal epithelial cells. Arch Ophthalmol. 1984;102:1830-1833.
18. Campochiaro PA, Glaser BM. Platelet-derived growth factor is chemotactic for human retinal epithelial cells. Arch Ophthalmol. 1985;103:576-579.
19. de Juan E, Dickson JS, Hjelmeland LM. Serum is chemotactic for retinal-derived glial cells. Arch Ophthalmol 1988;106:986-990.
20. Yeo JH, Sadeghi J, Campochiaro PA, et al. Intravitreous fibronectin and platelet-derived growth factor: new model for traction retinal detachment. Arch Ophthalmol. 1986;104:417-421.
21. Osborn M, Weber K. Intermediate filaments: cell-type specific markers in differentiation and pathology. Cell. 1982;31:303-306.
22. Messmer EP, Font RL. Applications of immunohistochemistry to ophthalmic pathology. Ophthalmology. 1984;91:701-707.
23. Guarino M. Epithelial-to-mesenchymal change of differentiation: from embryogenetic mechanism to pathological patterns. Histol Histopathol. 1995;10:171-184.
24. Blau HM. Differentiation requires continuous active control. Annu Rev Biochem. 1992;61:1213-1230.
25. Birchmeier C, Birchmeier W. Molecular aspects of mesenchymal-epithelial interactions. Annu Rev Cell Biol. 1993;9:511-540.
26. Birchmeier W, Birchmeier C. Epithelial-mesenchymal transitions in development and tumor progression. In: Goldberg ID, Rosen EM, eds. Epithelial-Mesenchymal Interactions in Cancer. Basel, Switzerland: Birkhäuser Verlag; 1995:1-15.
27. Greenbury G, Hay ED. Cytodifferentiation and tissue phenotype change during transformation of embryonic lens epithelium to mesenchymal-like cells in vitro. Dev Biol. 1986;115:363-379.
28. Pagan R, Martín I, Alonso A, Llobera M, Vilaró, S. Vimentin filaments follow the preexisting cytokeratin network during epithelial-mesenchymal transition of cultured neonatal rat hepatocytes. Exp Cell Res. 1996;222:333-344.
29. Hay ED. Extracellular matrix alters epithelial differentiation. Curr Opin Cell Biol. 1993;5:1029-1035.
30. Hunt R, Davis A. Altered expression of keratin and vimentin in human retinal pigment epithelial cells in vivo and in vitro. J Cell Physiol. 1990;145:187-199.
31. Flood M, Gouras P, Kjeldbye H. Growth characteristics and ultrastructure of human retinal pigment epithelium in vitro. Invest Ophthalmol Vis Sci. 1980;19:1309-1320.
32. Franke WW. Separation of cytokeratin polypeptides by gel electrophoretic and chromatographic techniques and their identification by immunoblotting. Methods Enzymol. 1986;134:355-371.
33. Casaroli-Marano RP, Vilaró S. The role of fibronectin, laminin, vitronectin and their receptors on cellular adhesion in proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci. 1994;35:2791-2803.
34. 4. Nature. 1970;72:248-254.
35. Towbin H, Gordon J. Immunoblotting and dot immunobinding: current status and outlook. J Immunol Methods. 1984;72:313-340.
36. Gigi O, Geiger B, Eshhar Z, et al. Detection of a cytokeratin determinant common to diverse epithelial cells by a broadly cross-reacting monoclonal antibody. EMBO J. 1982;1:1429-1437.
37. Vinores SA, Campochiaro PA, Conway P. Ultrastructural and electron-immunocytochemical characterization of cells in epiretinal membranes. Invest Ophthalmol Vis Sci. 1990;31:14-28.
38. Vinores SA, Van Neil E, Kim H, et al. Simultaneous expression of keratin and glial fibrillary acidic protein by some cells in epiretinal membranes. Invest Ophthalmol Vis Sci. 1992;33:3361-3366.
39. Bignami A, Dahl D. The radial glia of Müller in the rat retina and their response to injury: an immunofluorescence study with antibodies to the glial fibrillary acidic (GFA) protein. Exp Eye Res. 1979;28:63-69.
40. Björklund H, Bignami A, Dahl D. Immunohistochemical demonstration of glial fibrillary acidic protein in normal rat Müller glia and retinal astrocytes. Neurosci Lett. 1985;54:363-367.
41. Shaw G, Weber K. The structure and development of the rat retina: an immunofluorescence microscopical study using antibodies specific for intermediate filament proteins. Eur J Cell Biol. 1983;30:219-225.
42. Okada M, Matsumura M, Ogino N, et al. Müller cells in detached human retina express glial fibrillary acidic protein and vimentin. Graefe's Arch Clin Exp Ophthalmol. 1990;228:467-470.
43. Pixley SKR, de Vellis J. Transition between immature radial glia and mature astrocytes studies with a monoclonal antibody to vimentin. Dev Brain Res. 1984;15:201-206.
44. Sharp G, Osborn M, Weber K. Occurrence of two different intermediate filament proteins in the same filament in situ within a human glioma cell line. Exp Cell Res. 1982;141:385-389.
45. Abd-El-Basset EM, Ahmed I, Kalnins V, Fedoroff S. Immuno-electron microscopical localization of vimentin and glial fibrillary acidic protein in mouse astrocytes and their precursor cells in culture. Glia. 1992;6:149-153.
46. Glaser B, Cardin A, Biscoe B. Proliferative vitreoretinopathy: the mechanism of development of vitreoretinal traction. Ophthalmology. 1987;94:327-332.
47. Allamby D, Foreman D, Carrington L, et al. Cell attachment to, and contraction of, the retina in vitro. Invest Ophthalmol Vis Sci. 1997;38:2064-2072.
48. McKay BS, Burke JM. Separation of phenotypically distinct subpopulations of cultured human retinal pigment epithelial cells. Exp Cell Res. 1994;213:85-92.
49. Davis AA, Berstein PS, Bok D, Turner J, Nachtigal M, Hunt RC. A human retinal epithelial cell line that retains epithelial characteristics after prolonged culture. Invest Ophthalmol Vis Sci. 1995;36: 955-964.
50. Grisanti S, Guidry C. Transdifferentiation of retinal pigment epithelial cells from epithelial to mesenchymal phenotype. Invest Ophthalmol Vis Sci. 1995;36:391-405.
51. Burke JM, Skumatz CMB, Irving PEI, McKay BS. Phenotypic heterogeneity of retinal pigment epithelial cells in vitro and in situ. Exp Eye Res. 1996;62:63-73.
52. Robey HL, Hiscott PS, Grierson I. Cytokeratins and retinal epithelial cell behaviour. J Cell Sci. 1992;102:329-340.
53. Fuchs U, Kivelä T, Tarkkanen A. Cytoskeleton in normal and reactive human retinal epithelial cells. Invest Ophthalmol Vis Sci. 1991;32:3178-3186.
54. Schaafsma HE, Ramaekers FCS, Van Muijen GNP, et al. Distribution of cytokeratin polypeptides in human transitional cell carcinomas, with special emphasis on changing expression patterns during tumour progression. Am J Pathol. 1990;136:329-343.
55. Nagle RB, Brawer MK, Kittelson J, Clark V. Phenotypic relationships of prostatic intraepithelial neoplasia to invasive prostatic carcinoma. Am J Pathol. 1991;138:119-128.