Mitochondrial DNA damage and the involvement of antioxidant defense and repair system in hippocampi of rats with chronic seizures

Cellular and Molecular Neurobiology

Volumn 30, Issue 6, 2010, Pages 947-954

  Lin, Youting ^a   Han, Yuxiang ^a   Xu, Jingjing ^b   Cao, Lili ^a   Gao, Jing ^c   Xie, Nanchang ^a   Zhao, Xiuhe ^a   Jiang, Hong ^b   Chi, Zhaofu ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

^c QINGDAO UNIVERSITY   (China)

Author keywords

Antioxidants; Epilepsy; Hippocampus; Mitochondrial base excision repair; Mitochondrial DNA damage; Oxidative stress; Pilocarpine

Indexed keywords

DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; DNA DIRECTED DNA POLYMERASE GAMMA; GLUTATHIONE; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; CONTROLLED STUDY; DNA DAMAGE; EPILEPSY; EPILEPTOGENESIS; EXCISION REPAIR; HIPPOCAMPUS; MALE; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; CHRONIC DISEASE; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA, MITOCHONDRIAL; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; DNA-DIRECTED DNA POLYMERASE; GENE DOSAGE; GENE EXPRESSION REGULATION; GLUTATHIONE; HIPPOCAMPUS; MITOCHONDRIA; OXIDATION-REDUCTION; POLYMERASE CHAIN REACTION; RATS; RNA, MESSENGER; SEIZURES; TRANSCRIPTION FACTORS;

RATTUS;

EID: 77956183217     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10571-010-9524-x     Document Type: Article

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