Melatonin protects hippocampal neurons in vivo against kainic acid- induced damage in mice

Journal of Neuroscience Research

Volumn 54, Issue 3, 1998, Pages 382-389

  Tan, Dun Xian ^a   Manchester, Lucien C ^a   Reiter, Russel J ^a   Qi, Wenbo ^a   Kim, Seok Joong ^a   El Sokkary, Gamal H ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Free radical; Hippocampus; Kainic acid; Lipid peroxidation; Melatonin; Mice

Indexed keywords

FREE RADICAL; KAINIC ACID; MELATONIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; BRAIN PROTECTION; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; HIPPOCAMPUS; INTRAPERITONEAL DRUG ADMINISTRATION; LIPID PEROXIDATION; MOUSE; NERVE CELL LESION; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SEIZURE; STROKE; SUBCUTANEOUS DRUG ADMINISTRATION; TREMOR;

ANIMALS; CELL MEMBRANE; CELL NUCLEUS; KAINIC ACID; LIPID PEROXIDATION; MALE; MELATONIN; MICE; NERVOUS SYSTEM DISEASES; NEUROPROTECTIVE AGENTS; PYRAMIDAL CELLS; RANDOM ALLOCATION;

EID: 0032213419     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19981101)54:3<382::AID-JNR9>3.0.CO;2-Y     Document Type: Article

References (57)

1. Acuna-Castroviejo D, Escames G, Macias M, Munoz-Hoyos A, Molia-Carballo A, Aravzo M, Montes R., Vives F (1995): Cell protective role of melatonin in the brain. J Pineal Res 19:57-63.
2. Albertson TE, Peterson SL, Stark LG, Lakin ML, Winters WD (1981): The anticovulsant properties of melatonin on kindled seizures in rats. Neuropharmacology 20:61-66.
3. Antolin I, Rodriguez C, Sainz RM, Mayo JC, Uria H, Kotler ML, Rodriguez-Colunga MJ, Tolivia D, Menendez-Pelaez A (1996): Neurohormone melatonin prevents cell damage: Effect on gene expression for antioxidant enzymes. FASEB J10:882-890.
4. Barlow-Walden LR, Reiter RJ, Abe M, Pablos MI, Menendez-Pelaez A, Chen L.D, Poeggeler B (1995): Melatonin stimulates brain glutathione peroxidase activity. Neurochem Int 26:497-520.
5. 2 and cyclic AMP production in rat hypothalamus: A mechanism involving inhibition of nitric oxide synthase. J Pineal Res 25:34-40.
6. Bradford MM (1976): A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem 72:248-254.
7. Ruckmaster PS, Duked FE (1997): Neuron loss, granule cell axon reorganization, and functional changes in the dentate gyrus of epileptic kainate-treated rats. J Comp Neurol 385:385-404.
8. Cazevieille C, Osborne NN (1997): Retinal neurons containing kainate receptors are influenced by exogenous kainate and ischaemia while neurons lacking these receptors are not: Melatonin counteracts the effect of ischaemia and kainate. Brain Res 755:91-100.
9. Champney T H, Hanneman WH, Legare ME, Appel K (1996): Acute and chronic effects of melatonin as an anticovulsant in male gerbils. J Pineal Res 20:79-83.
10. Cuzzocrea S, Zigarelli B, Gilad E, Hake P, Salzman AL, Szabo C (1997): Protective effect of melatonin in carrageenan-induced models of local inflammation. J Pineal Res 23:106-166.
11. Daniels WMU, van Rensburg SJ, van Zyl JM, Taljaard JJF (1998): Melatonin prevents β-amyloid-induced lipid peroxidation. J Pineal Res 24:78-82.
12. Davies P (1985): A critical review of the role of the cholinergic system in human memory and cognition. Ann NY Acad Sci 444:212-217.
13. Dykens JA, Stem A, Trenker E (1987): Mechanism of kainate toxicity to cerebellar neurons in vitro is analogous to reperfusion tissue injury. J Neurochem 491:222-1228.
14. Floreani M, Skaper SD, Facci L, Lipartiti M, Giusti P (1997): Melatonin maintains glutathione homeostasis in kainic acid-exposed rat brain tissues. FASEB J 11:1309-1315.
15. Garcia JJ, Reiter RJ, Guerrero JM, Escames G, Yu BP, Oh CS, Munoz-Hoyos A (1997): Melatonin prevents changes in microsomal membrane fluidity during induced lipid peroxidation. FEBS Lett 408:297-300.
16. Garcia JJ, Reiter RJ, Ortiz GG, Oh CS, Tang L, Yu BP, Escames G (1998): Melatonin enhances tamoxifen's ability to prevent the reduction in microsomal membrane fluidity induced by lipid peroxidation. J Membr Biol 162:59-65.
17. Giusti P, Gusella M, Lipartiti M, Milani D, Zhu W, Vicini S, Manev H (1995): Melatonin protects primary cultures of cerebellar granule neurons from kainate but not from N-methyl-D-aspartate excitotoxicity. Exp Neurol 131:39-46.
18. Giusti P, Lipartiti M, Franceschini D, Schiavo N, Floreani M, Manev H (1996a): Neuroprotection by melatonin from kainate-induced excitotoxicity in rats. FASEB J 10:891-896.
19. Giusti P, Franceschini D, Petrone M, Manev H, Floreani M (1996b): In vitro and in vivo protection against kainate-induced excitotoxicity by melatonin. J Pineal Res 20:226-231.
20. Kabuto H, Yokoi I, Ogawa N (1998): Melatonin inhibits iron-induced epileptic discharges in rats by suppressing peroxidation. Epilepsia 39:237-243.
21. Kesner RP (1985): Correspondence between humans and animals in coding of temporal attributes: Role of hippocampus and prefrontal cortex. Ann NY Acad Sci 444:122-136.
22. Lipartiti M, Franceschini D, Zanoni R, Gusella M, Giusti P, Cagnoli CM, Kharlamov A, Manev H (1996): Neuroprotective effects of melatonin. In Filippini GA et al. (eds): "Recent Advances in Tryptophan Research." New York: Plenum Press, pp. 315-321.
23. Manev H, Uz T, Kharlamov A, Joo JY (1996): Increased brain damage after stroke or excitotoxic seizures in melatonin-deficient rats. FASEB J 10 1546-1551.
24. Melchiorri D, Reiter RJ, Attia AM, Burgos A, Nistico G (1994): Potent protective effect of melatonin on in vivo paraquat-induced oxidative damage in rats. Life Sci 56: 83-89.
25. Melchiorri D, Reiter RJ, Sewerynek E, Chen LD, Nistico G (1995): Melatonin reduces kainate-induced lipid peroxidation in homogenates of different brain regions. FASEB J 9:1205-1210.
26. Melchiorri D, Reiter RJ, Chen LD, Sewerynek E, Nistico G (1996): Melatonin affords protection against kainate-induced in vitro lipid peroxidation in brain. Eur J Pharmacol 305:239-241.
27. Menendez-Pelaez A, Poeggeler B, Reiter RJ, Barlow-Walden L, Pablos MI, Tan DX (1993a): Nuclear localization of melatonin in different mammalian tissues: Immunocytochemical and radioimmunoassay evidence. J Cell Biochem 53:373-282.
28. Menendez-Pelaez A, Reiter RJ (1993b): Distribution of melatonin in mammalian tissues: The importance of nuclear versus cytosolic localization. J Pineal Res 15:59-67.
29. Mesenge C, Margaill I, Verrecchia C, Allix M, Boula RG, Plotkine M (1998): Protective effect of melatonin in a model of traumatic brain injury in mice. J Pineal Res 25:41-46.
30. Mink JW, Thach WT (1991): Basal ganglia motor control. III. Pallidal ablation: Normal reaction time, muscle contraction, and slow movement. J Neurophysiol 65:330-351.
31. Molina-Carballo A, Munoz-Hoyos A, Reiter RJ, Sanchez-Forte M, Moreno-Madrid F, Campos M, Molina-Font JA, Acuna-Castroviejo D (1997): Utility of high doses of melatonin as adjanctive anticonvulsant therapy in a child with severe myoclonic epilepsy: Two year's experience. J Pineal Res 23:97-105.
32. Noda Y, Mori A, Liburty R, Packer L (1998): Melatonin and its precusors exhibit nitric oxide scavenging ability. Pathophysiology 5:85.
33. Ong WY, He Y, Garey LJ (1997): Distribution of amyloid beta-protein immunoreactivity in the hippocampus of rats injected with kainate. J Hirnforsch 38:353-361.
34. Pablos MI, Reiter RJ, Ortiz GG, Guerrero JM, Agapito MT, Chuang JI, Sewerynek E (1998): Rhythms of glutathione peroxidase and glutathione reductase in brain of chick and their inhibition by light. Neurochem Int 32:69-75.
35. Pappolla MA, Sos M, Omar RA, Bick RJ, Dickson-Bick DLM, Reiter RJ, Ethhimiopoulos S, Robakis NK (1997): Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide. J Neurosci 17:1683-1690.
36. Pieri C, Marra M, Monori F, Recchioni R, Marcheselli F (1994): Melatonin: A peroxyl radical scavenger more effective than vitamin E. Life Sci 55:271-276.
37. Pierrefiche G, Laborit H (1995): Oxygen free radicals, melatonin, and aging. Exp Gerontol 30:213-227.
38. Pozo D, Reiter RJ, Calvo JR, Guerrero JM (1997) Inhibition of nitric oxide synthase and cyclic GMP production by physiological concentrations of melatonin in the rat cerebellum: A calmodulin-mediated mechanism. J Cell Biochem 65:430-442.
39. Reiter RJ (1995): Oxidative processes and antioxidative defense mechanisms in the aging brain. FASEB J 9:525-533.
40. Reiter RJ, Blask DE, Talbot JA, Barnett MP (1973): Nature and the time course of seizures associated with surgical removal of the pineal gland from parathyroidectomized rats. Exp Neurol 38: 386-397.
41. Reiter RJ, Tan DX, Poeggeler B, Menendez-Pelaez A, Chen LD, Saarela S (1994): Melatonin as free radical scavenger: Implications for aging and age-related diseases. Ann NY Acad Sci 719:1-12.
42. Reiter RJ, Guerrero JM, Escames G, Pappolla MA, Acuna-Castroviejo D (1997): Prophylactic actions of melatonin in oxidative neurotoxicity. Ann NY Acad Sci 825:70-78.
43. Reiter RJ, Tan DX, Kim SJ, Qi W (1998a): Melatonin as a pharmacological agent against oxidative damage to lipids and DNA. Proc West Pharmacol Soc, in press.
44. Reiter RJ, Garcia JJ, Pie J (1998b): Oxidative toxicity in models of neurodegeneration: Responses to melatonin. Restor Neurol Neurosci, in press.
45. Rodriquez AB, Nogales G, Ortega E, Barringa C (1998): Melatonin controls Superoxide anion level: Modulation of Superoxide dismutase activity in ring dove heterophils. J Pineal Res 24:9-14.
46. Schulz JB, Henshaw DR, Siwek D, Jenkins BG, Ferrante RJ, Cipolloni PB, Kowall N, Rosen BR, Beal MF (1995): Involvement of free radicals in excitotoxicity in vivo. J Neurochem 64:2239-2247.
47. Schwarzer C, Tsunashima K, Wanzenbock C, Sieghart K, Sperk G (1997): GABA(A) receptor subunits in the rat hippocampus. II. Altered distribution in kainic acid-induced temporal lobe epilepsy. Neuroscience 80:1001-1017.
48. Shoham S, Ebstein RP (1997): The distribution of beta-amyloid precursor protein in rat cortex after systemic kainate-induced seizure. Exp Neurol 147:361-367.
49. Sperk G, Lassmann H, Baram H, Kish SJ, Seitelberger F, Hornykiewicz O (1983): Kainic acid induced seizures: Neurochemical and histopathological changes. Neuroscience 10:1301-1315.
50. Tan DX, Chen LD, Poeggeler B, Manchester LC, Reiter RJ (1993a): Melatonin: A potent, endogenous hydroxyl radical scavenger. Endocrine J 1:57-60.
51. Tan DX, Poeggeler B, Reiter RJ, Chen LD, Manchester LC, Barlow-Walden LR (1993b): The pineal hormone melatonin inhibits DNA-adduct formation induced by the chemical carcinogen safrole in vivo. Cancer Lett 70:65-70.
52. Tan DX, Reiter RJ, Chen LD, Poeggeler B, Manchester LC, Barlow-Walden LR (1994): Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole. Carcinogenesis 15:215-218.
53. Tang L, Reiter RJ, Li ZR, Ortiz GG, Yu BP, Garcia JJ (1998): Melatonin reduces the increase in 8-hydroxy-deoxyguanosine levels in the brain and liver of kainic acid-treated rats. Mol Cell Biochem 178:299-303.
54. Uz T, Giusti P, Franceschini D, Kharlamov A, Manev H (1996): Protective effect of melatonin against hippocampal DNA damage induced by intraperitoneal administration of kainate to rats. Neuroscience 73:631-636.
55. Yamamoto HA, Tang HW (1996a): Antagonistic effect of melatonin against cyanide-induced seizures and acute lethality in mice. Toxicol Lett 87:19-24.
56. Yamamoto HA, Tang HW (1996b): Melatonin attenuates L-cysteine-induced seizures and lipid peroxidation in the brain of mice. J Pineal Res 21:108-113.
57. Zaaroor M, Starr A (1997): Experimental facial myokymia in cat. Acta Neurol Scand 95:19-22.