Seizure-induced changes in energy metabolites and effects of N-tert-butyl-α-phenylnitrone (PNB) and vitamin E in rats

Pflugers Archiv European Journal of Physiology

Volumn 440, Issue SUPPL. 5, 2000, Pages

  Gupta, Ramesh C ^a   Milatovic, Dejan ^b   Zivin, Marko ^c   Dettbarn, Wolf D ^b  

^a MURRAY STATE UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

High energy phosphates; Kainic acid (KA); Oxidative stress; Seizures

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ALPHA TOCOPHEROL; CREATINE; CREATINE PHOSPHATE; KAINIC ACID; N TERT BUTYL ALPHA PHENYLNITRONE; ADENINE NUCLEOTIDE; ANTIOXIDANT; PHOSPHATE;

AMYGDALOID NUCLEUS; ANIMAL MODEL; CONFERENCE PAPER; CONTROLLED STUDY; ENERGY METABOLISM; EPILEPTIC STATE; HIPPOCAMPUS; MALE; NERVE CELL LESION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PYRIFORM CORTEX; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEIZURE; AMYGDALA; ANIMAL EXPERIMENT; ARTICLE; HIGH ENERGY PHOSPHATE; QUANTITATIVE ANALYSIS;

EID: 0033830870     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240000047     Document Type: Conference Paper

References (5)

1. Ketamine, phencyclidine and MK-801 protect against kainic acid induced seizure-related brain damage
2. Antioxidant pretreatment prevents seizure-induced loss of cytochrome c oxidase and high-energy phosphate depletion in brain regions of rat
3. N-tert-butyl-α-phenylnitrone improves recovery of brain energy state in rats following transient focal ischemia
4. Alterations of high-energy phosphate compounds in the skeletal muscles of rats intoxicated with diisopropylphosphorofluoridate (DFP) and soman
5. Neuronal degeneration after intracerebral injections of excitotoxins. A histological analysis of kainic acid, ibotenic and quinolinic acid lesions in the brain