Anti-apoptotic activity of gentiopicroside in d-galactosamine/lipopolysaccharide-induced murine fulminant hepatic failure

Chemico-Biological Interactions

Volumn 188, Issue 1, 2010, Pages 127-133

  Lian, Li Hua ^a   Wu, Yan Ling ^a   Wan, Ying ^a   Li, Xin ^a   Xie, Wen Xue ^a   Nan, Ji Xing ^a  

^a YANBIAN UNIVERSITY   (China)

Author keywords

Apoptosis; C jun N terminal kinase (JNK); D Galactosamine (d GalN) lipopolysaccharide (LPS); Extracellular signal regulated kinase (ERK); Gentiopicroside; Tumor necrosis factor (TNF)

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; DNA; GALACTOSAMINE; GENTIOPICRIN; GLUTATHIONE; LIPID; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; SILYMARIN; SODIUM CHLORIDE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; CASPASE; GLUCOSIDE; IRIDOID;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOSOL; DNA FRAGMENTATION; DRUG DOSE COMPARISON; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; INHIBITION KINETICS; LETHALITY; LIPID PEROXIDATION; LIVER CELL; LIVER FAILURE; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; ANIMAL; BIOSYNTHESIS; BLOOD; C57BL MOUSE; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; PATHOLOGY; TOXICITY; WESTERN BLOTTING;

ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; BLOTTING, WESTERN; CASPASES; ENZYME ACTIVATION; GALACTOSAMINE; GLUCOSIDES; GLUTATHIONE; IRIDOIDS; LIPID PEROXIDATION; LIPOPOLYSACCHARIDES; LIVER FAILURE; MALE; MICE; MICE, INBRED C57BL; TUMOR NECROSIS FACTOR-ALPHA; IRIDOID GLUCOSIDES;

MURINAE; MUS;

EID: 77956170862     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.06.004     Document Type: Article

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