Down-regulation of NR2B receptors partially contributes to analgesic effects of Gentiopicroside in persistent inflammatory pain

Neuropharmacology

Volumn 54, Issue 8, 2008, Pages 1175-1181

  Chen, Lei ^a   Liu, Jin cheng ^b   Zhang, Xiao nan ^c   Guo, Yan yan ^c   Xu, Zhao hui ^c   Cao, Wei ^c   Sun, Xiao li ^c   Sun, Wen ji ^a   Zhao, Ming Gao ^c  

^a NORTHWEST UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Anterior cingulate cortex; Gentiopicroside; Inflammation; NMDA receptor; Pain

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; CYCLIC AMP; GENTIOPICRIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL TISSUE; ARTICLE; CINGULATE GYRUS; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNAPTIC TRANSMISSION;

ANALGESICS, NON-NARCOTIC; ANIMALS; BLOTTING, WESTERN; CHRONIC DISEASE; CYCLIC AMP; DOWN-REGULATION; EXCITATORY POSTSYNAPTIC POTENTIALS; FREUND'S ADJUVANT; GLUCOSIDES; GLUTAMIC ACID; INFLAMMATION; IRIDOIDS; MICE; MICE, INBRED C57BL; PAIN; PAIN MEASUREMENT; PATCH-CLAMP TECHNIQUES; RECEPTORS, GABA-A; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPTIC TRANSMISSION;

EID: 43949139231     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2008.03.007     Document Type: Article

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