Tumor suppressor p27Kip1 undergoes endolysosomal degradation through its interaction with sorting nexin 6

FASEB Journal

Volumn 24, Issue 8, 2010, Pages 2998-3009

  Fuster, José J ^a,b   González, José M ^a   Edo, María D ^a   Viana, Rosa ^a   Boya, Patricia ^c   Cervera, Javier ^d   Verges, Marcel ^d   Rivera, José ^b   Andrés, Vicente ^a,b  

^a INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

^b CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^c CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^d CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

Author keywords

Cell cycle; Endosome; Lysosome; Proteolysis; SNX6

Indexed keywords

BIOLOGICAL MARKER; CYCLIN DEPENDENT KINASE INHIBITOR 1B; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; PROTEIN; PROTEIN ANTIBODY; SORTING NEXIN 6; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL ORGANELLE; CELL STRAIN 3T3; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; ENDOSOME; FEMALE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; LYSOSOME; MAMMAL CELL; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

ANIMALS; CARRIER PROTEINS; CELL CYCLE; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P27; HUMANS; LYSOSOMES; MICE; PROTEIN BINDING; VESICULAR TRANSPORT PROTEINS;

MAMMALIA;

EID: 77955795702     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-138255     Document Type: Article

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