Structural characterization of two poreforming peptides: Consequences of introducing a C-terminal tryptophan

Proteins: Structure, Function and Bioinformatics

Volumn 78, Issue 10, 2010, Pages 2238-2250

  Herrera, Alvaro I ^a   Al Rawi, Ahlam ^a   Cook, Gabriel A ^a,b   Gao, Jian ^a   Iwamoto, Takeo ^a   Prakash, Om ^a   Tomich, John M ^a   Chen, Jianhan ^a  

^a KANSAS STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Anion selectivity; Ion channel; Micelles; Molecular dynamics; Molecular modeling; Solution NMR; Structure refinement; Synthetic channel

Indexed keywords

GLYCINE RECEPTOR; POLYPEPTIDE; PORE FORMING CYTOTOXIC PROTEIN; TRYPTOPHAN; 1-PALMITOYL-2-OLEOYLPHOSPHATIDYLCHOLINE; 2 OLEOYL 1 PALMITOYLPHOSPHATIDYLCHOLINE; ANION; CHLORIDE; CHLORIDE CHANNEL; PEPTIDE; PHOSPHATIDYLCHOLINE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; CHANNELOPATHY; CHLORIDE CONDUCTANCE; CHLORIDE TRANSPORT; ION CONDUCTANCE; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN STABILITY; PROTEIN STRUCTURE; SIMULATION; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; DRUG DEVELOPMENT; ELECTROCHEMICAL ANALYSIS; ION TRANSPORT; KINETICS; LIPID BILAYER; MICELLE; MOLECULAR DYNAMICS; MOLECULAR MIMICRY; PROTEIN CONFORMATION; PROTEIN DATABASE; SYNTHESIS; VALIDATION STUDY;

ANIONS; CHLORIDE CHANNELS; CHLORIDES; COMPUTATIONAL BIOLOGY; DATABASES, PROTEIN; DRUG DISCOVERY; ELECTROCHEMICAL TECHNIQUES; ION TRANSPORT; KINETICS; LIPID BILAYERS; MICELLES; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR MIMICRY; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDES; PHOSPHATIDYLCHOLINES; PROTEIN CONFORMATION; RECEPTORS, GLYCINE; TRYPTOPHAN;

EID: 77955788241     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22736     Document Type: Article

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