Conformational heterogeneity of the M2 proton channel and a structural model for channel activation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 32, 2009, Pages 13311-13316

  Yi, Myunggi ^a,b   Cross, Timothy A ^b,c   Zhou, Huan Xiang ^a,b  

^a Florida State University   (United States)

^b FLORIDA STATE UNIVERSITY   (United States)

^c FLORIDA STATE UNIVERSITY   (United States)

Author keywords

Amantadine; Helix kink; Histidine tetrad; MD simulations; Solid state NMR

Indexed keywords

AMANTADINE; GLYCINE; MEMBRANE PROTEIN; PROTEIN M2; PROTON; TRYPTOPHAN; WATER;

ARTICLE; HYDROGEN BOND; MEMBRANE CHANNEL; MOLECULAR DYNAMICS; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTON TRANSPORT; SIMULATION; STRUCTURAL PROTEOMICS;

AMANTADINE; AMINO ACIDS; BINDING SITES; COMPUTER SIMULATION; HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; REPRODUCIBILITY OF RESULTS; SALTS; VIRAL MATRIX PROTEINS; WATER;

INFLUENZAVIRUS A;

EID: 69549104773     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0906553106     Document Type: Article

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