Glycyrrhizic acid and 18β-glycyrrhetinic acid inhibit inflammation via PI3K/Akt/GSK3β signaling and glucocorticoid receptor activation

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 15, 2010, Pages 8623-8629

  Kao, Tzu Chien ^a   Shyu, Ming Huan ^a   Yen, Gow Chin ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

18 glycyrrhetinic acid; anti inflammation; glucocorticoid receptor; Glycyrrhizic acid; GSK3 phosphorylation; PI3K Akt signaling pathway

Indexed keywords

AIRWAY INFLAMMATION; ANTI-INFLAMMATION; ANTI-INFLAMMATORY ACTIVITY; CHRONIC OBSTRUCTIVE PULMONARY DISEASE; CYTOKINE PRODUCTION; DIFFERENT MECHANISMS; GLUCOCORTICOID RECEPTOR; GLYCYRRHIZIC ACID; INFLAMMATORY DISEASE; LUNG DISEASE; LUNG INFLAMMATION; NEUROPROTECTIVE AGENTS; NUTRACEUTICALS; PI3K/AKT SIGNALING PATHWAY;

BIOLOGICAL ORGANS; DISEASES; PHOSPHORYLATION; SIGNALING;

PATHOLOGY;

GLYCYRRHIZA;

18ALPHA GLYCYRRHETINIC ACID; 18ALPHA-GLYCYRRHETINIC ACID; ANTIINFLAMMATORY AGENT; DRUG DERIVATIVE; GLUCOCORTICOID RECEPTOR; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; GLYCYRRHETINIC ACID; GLYCYRRHIZIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL; ARTICLE; CELL LINE; DOWN REGULATION; DRUG EFFECT; GENETICS; IMMUNOLOGY; INFLAMMATION; METABOLISM; MOUSE; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; DOWN-REGULATION; GLYCOGEN SYNTHASE KINASE 3; GLYCYRRHETINIC ACID; GLYCYRRHIZIC ACID; INFLAMMATION; MICE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, GLUCOCORTICOID; SIGNAL TRANSDUCTION;

EID: 77955694196     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf101841r     Document Type: Article

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