Neuroprotective effects of Glycyrrhizic acid and 18β-glycyrrhetinic acid in PC12 cells via modulation of the PI3K/Akt pathway

Journal of Agricultural and Food Chemistry

Volumn 57, Issue 2, 2009, Pages 754-761

  Kao, Tzu Chien ^a   Shyu, Ming Huan ^a   Yen, Gow Chin ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

18 glycyrrhetinie acid; Glycyrrhizic acid; Mitochondria; Neuroprotection; PI3K Akt pathway

Indexed keywords

GLYCYRRHIZA;

18ALPHA GLYCYRRHETINIC ACID; 18ALPHA-GLYCYRRHETINIC ACID; APOPTOSIS REGULATORY PROTEIN; DRUG DERIVATIVE; GLYCYRRHETINIC ACID; GLYCYRRHIZIC ACID; NEUROPROTECTIVE AGENT; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE;

ANIMAL; APOPTOSIS; ARTICLE; CELL STRAIN; DRUG EFFECT; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; RAT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; GLYCYRRHETINIC ACID; GLYCYRRHIZIC ACID; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NEUROPROTECTIVE AGENTS; PC12 CELLS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 59849086862     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf802864k     Document Type: Article

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