The genome-wide association study-A new era for common polygenic disorders

Journal of Cardiovascular Translational Research

Volumn 3, Issue 3, 2010, Pages 173-182

  Roberts, Robert ^b   Wells, George A ^a   Stewart, Alexandre F R ^b   Dandona, Sonny ^b   Chen, Li ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b Ruddy Canadian Cardiovascular Genetics Centre   (Canada)

Author keywords

Coronary artery disease; Genetic predisposition; Genome wide association studies; Microarrays; Myocardial infarction; Polygenic disorders

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; DNA; LOW DENSITY LIPOPROTEIN; ORGANIC CATION TRANSPORTER 3; POTASSIUM CHANNEL KCNE2; STROMAL CELL DERIVED FACTOR 1;

BIOINFORMATICS; BRUGADA SYNDROME; CARDIOVASCULAR RISK; CHROMOSOME 9P; CORONARY ARTERY DISEASE; DNA SEQUENCE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC DISORDER; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HAPLOTYPE; HEART ATRIUM FIBRILLATION; HEART INFARCTION; HUMAN; HUMAN GENOME; HYPERTROPHIC CARDIOMYOPATHY; LONG QT SYNDROME; PRIORITY JOURNAL; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; WOLFF PARKINSON WHITE SYNDROME; ANIMAL; CHROMOSOME 9; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENETIC DATABASE; GENETIC PREDISPOSITION; GENETICS; META ANALYSIS (TOPIC); MULTIFACTORIAL INHERITANCE; PHENOTYPE; PROCEDURES; RISK ASSESSMENT; RISK FACTOR; SAMPLE SIZE;

ANIMALS; CHROMOSOMES, HUMAN, PAIR 9; CORONARY ARTERY DISEASE; DATABASES, GENETIC; GENE EXPRESSION PROFILING; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; META-ANALYSIS AS TOPIC; MULTIFACTORIAL INHERITANCE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK ASSESSMENT; RISK FACTORS; SAMPLE SIZE;

ANIMALIA;

EID: 77955660227     PISSN: 19375387     EISSN: 19375395     Source Type: Journal    
DOI: 10.1007/s12265-010-9178-6     Document Type: Review

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