A common variant in chromosome 9p21 associated with coronary artery disease in Asian Indians

Journal of Genetics

Volumn 88, Issue 1, 2009, Pages 113-118

  Maitra, Arindam ^a   Dash, Debabrata ^a   John, Shibu ^b   Sannappa, Prathima R ^a   Das, Anupam P ^a   Shanker, Jayashree ^a   Rao, Veena S ^c   Sridhara, H ^b   Kakkar, Vijay V ^d,e  

^a Mary and Garry Weston Functional Genomics Unit   (India)

^b Elizabeth and Emmanuel Kaye Bioinformatics and Statistics Unit   (India)

^c Tata Proteomics and Coagulation Unit   (India)

^d Narayana Health City   (India)

^e THROMBOSIS RESEARCH INSTITUTE   (United Kingdom)

Author keywords

9p21; Asian Indians; Coronary artery disease; Genomic variant; Human genetics; Myocardial infarction

Indexed keywords

ARTICLE; ASIAN; CHROMOSOME 9; CORONARY ARTERY DISEASE; ETHNOLOGY; FEMALE; GENETIC VARIABILITY; GENETICS; GENOTYPE; HUMAN; INDIA; MALE; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; PILOT STUDY; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

ASIAN CONTINENTAL ANCESTRY GROUP; CHROMOSOMES, HUMAN, PAIR 9; CORONARY ARTERY DISEASE; DIABETES MELLITUS, TYPE 2; FEMALE; GENETIC VARIATION; GENOTYPE; HUMANS; INDIA; MALE; MIDDLE AGED; PILOT PROJECTS; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 69449102288     PISSN: 00221333     EISSN: 09737731     Source Type: Journal    
DOI: 10.1007/s12041-009-0017-y     Document Type: Article

References (34)

1. Abdullah K. G., Li L., Shen G. Q., Hu Y., Yang Y., Mackinlay K. G. et al. 2008 Four SNPS on chromosome 9p21 confer risk to premature, familial CAD and MI in an American Caucasian population (GeneQuest). Ann. Hum. Genet. 72, 654-657.
2. Arvind K., Pradeepa R., Deepa R. and Mohan V. 2002 Diabetes and coronary artery disease. Indian J. Med. Res. 116, 163-176.
3. Barrett J. C., Fry B., Maller J. and Daly M. J. 2005 Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21, 263-265.
4. Broadbent H. M., Peden J. F., Lorkowski S., Goel A., Ongen H., Green F. et al. 2008 Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p. Hum. Mol. Genet. 17, 806-814.
5. Chambers J. C., Eda S., Bassett P., Karim Y., Thompson S. G., Gallimore J. R. et al. 2001 C-reactive protein, insulin resistance, central obesity, and coronary heart disease risk in Indian Asians from the United Kingdom compared with European whites. Circulation 104, 145-150.
6. Friedewald W. T., Levy R. I. and Fredrickson D. S. 1972 Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 18, 499-502.
7. Goyal A. and Yusuf S. 2006 The burden of cardiovascular disease in the Indian subcontinent. Indian J. Med. Res. 124, 235-244.
8. Helgadottir A., Thorleifsson G., Manolescu A., Gretarsdottir S., Blondal T., Jonasdottir A. et al. 2007 A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science 316, 1491-1493.
9. Helgadottir A., Thorleifsson G., Magnusson K. P., Gretarsdottir S., Steinthorsdottir V., Manolescu A. et al. 2008 The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. Nat. Genet. 40, 217-224.
10. Hinohara K., Nakajima T., Takahashi M., Hohda S., Sasaoka T., Nakahara K. et al. 2008 Replication of the association between a chromosome 9p21 polymorphism and coronary artery disease in Japanese and Korean populations. J. Hum. Genet. 53, 357-359.
11. Indian Genome Variation Consortium 2008 Genetic landscape of the people of India: a canvas for disease gene exploration. J. Genet. 87, 3-20.
12. International HapMap Consortium 2005 A haplotype map of the human genome. Nature 437, 1299-1320.
13. Kanjilal S., Shanker J., Rao V. S., Khadrinarasimhaih N. B., Mukherjee M., Iyengar S. S. et al. 2008 Prevalence and component analysis of metabolic syndrome: an Indian atherosclerosis research study perspective. Vasc. Health Risk Manage. 4, 189-197.
14. Kooner J. S., Chambers J. C., Aguilar-Salinas C. A., Hinds D. A., Hyde C. L., Warnes G. R. et al. 2008 Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides. Nat. Genet. 40, 149-151.
15. Maitra A., Shanker J., Dash D., John S., Sannappa P. R., Rao V. S. et al. 2008 Polymorphisms in the IL6 gene in Asian Indian families with premature coronary artery disease - The Indian atherosclerosis research study. Thromb. Haemost. 99, 944-950.
16. Matarin M., Brown W. M., Singleton A., Hardy J. A. and Meschia J. F. 2008 Whole genome analyses suggest ischemic stroke and heart disease share an association with polymorphisms on chromosome 9p21. Stroke 39, 1586-1589.
17. McPherson R., Pertsemlidis A., Kavaslar N., Stewart A., Roberts R., Cox D. R. et al. 2007 A common allele on chromosome 9 associated with coronary heart disease. Science 316, 1488-1491.
18. Miller S. A., Dykes D. D. and Polesky H. F. 1988 A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16, 1215.
19. Papp A. C., Pinsonneault J. K., Cooke G. and Sadee W. 2003 Single nucleotide polymorphism genotyping using allele-specific PCR and fluorescence melting curves. Biotechniques 34, 1068-1072.
20. Rai T. S., Khullar M., Sehrawat B. S., Ahuja M., Sharma P. K., Vijayvergiya R. et al. 2008 Synergistic effect between apolipoprotein E and apolipoprotein A1 gene polymorphisms in the risk for coronary artery disease. Mol. Cell. Biochem. 313, 139-146.
21. Samani N. J., Erdmann J., Hall A. S., Hengstenberg C., Mangino M., Mayer B. et al. 2007 Genomewide association analysis of coronary artery disease. N. Engl. J. Med. 357, 443-453.
22. Saxena R., Voight B. F., Lyssenko V., Burtt N. P., de Bakker P. I., Chen H. et al. 2007 Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316, 1331-1336.
23. Schunkert H., Gotz A., Braund P., McGinnis R., Tregouet D. A., Mangino M. et al. 2008 Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease. Circulation 117, 1675-1684.
24. Shanker J., Kanjilal S., Rao V. S., Perumal G., Khadrinarasimhiah N. B., Mukherjee M. et al. 2007 Adult nontwin sib concordance rates for type 2 diabetes, hypertension and metabolic syndrome among Asian Indians: the Indian atherosclerosis research study. Vasc. Health Risk Manage. 3, 1063-1068.
25. Shanker J., Perumal G., Rao V. S., Khadrinarasimhiah N. B., John S., Hebbagodi S. et al. 2008 Genetic studies on the APOA1-C3-A5 gene cluster in Asian Indians with premature coronary artery disease. Lipids Health Dis. 7, 33-47.
26. Sharma M. and Ganguly N. K. 2005 Premature coronary artery disease in Indians and its associated risk factors. Vasc. Health Risk Manage. 1, 217-225.
27. Shen G. Q., Li L., Rao S., Abdullah K. G., Ban J.M., Lee B. S. et al. 2008 Four SNPs on chromosome 9p21 in a South Korean population implicate a genetic locus that confers high cross-race risk for development of coronary artery disease. Arterioscler. Thromb. Vasc. Biol. 28, 360-365.
28. Sole X., Guino E., Valls J., Iniesta R. and Moreno V. 2006 SNPStats: a web tool for the analysis of association studies. Bioinformatics 22, 1928-1929.
29. Tillin T., Dhutia H., Chambers J., Malik I., Coady E., Mayet J. et al. 2007 South Asian men have different patterns of coronary artery disease when compared with European men. Int. J. Cardiol 129, 406-413.
30. Topol E. J., Smith J., Plow E. F. and Wang Q. K. 2006 Genetic susceptibility to myocardial infarction and coronary artery disease. Hum. Mol. Genet. 2, R117-R123.
31. Wellcome Trust Case Control Consortium 2007 Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447, 661-678.
32. Ye S., Willeit J., Kronenberg F., Xu Q. and Kiechl S. 2008 Association of genetic variation on chromosome 9p21 with susceptibility and progression of atherosclerosis: a population-based, prospective study. J. Am. Coll. Cardiol. 52, 378-384.
33. Zdravkovic S., Wienke A., Pedersen N. L., Marenberg M. E., Yashin A. I. and De Faire U. 2002 Heritability of death from coronary heart disease: a 36-year follow-up of 20 966 Swedish twins. J. Intern. Med. 252, 247-254.
34. Zhou L., Zhang X., He M., Cheng L., Chen Y., Hu F. B. et al. 2008 Associations between single nucleotide polymorphisms on chromosome 9p21 and risk of coronary heart disease in Chinese Han population. Arterioscler Thromb. Vasc. Biol. 28, 2085-2089.