메뉴 건너뛰기




Volumn 17, Issue 26, 2010, Pages 2906-2920

Drug target identification for neuronal apoptosis through a genome scale screening

Author keywords

Apoptosis; Drug; Neuronal; Pharmacogenomics; Programmed cell death; Systems biology; Target

Indexed keywords

GASTRIC INHIBITORY POLYPEPTIDE;

EID: 77955637983     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986710792065081     Document Type: Article
Times cited : (8)

References (118)
  • 1
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim, R.W. Cell death during development of the nervous system. Annu. Rev. Neurosci., 1991, 14, 453-501.
    • (1991) Annu. Rev. Neurosci , vol.14 , pp. 453-501
    • Oppenheim, R.W.1
  • 2
    • 0032055973 scopus 로고    scopus 로고
    • Neuronal cell death
    • Pettmann, B.; Henderson, C.E. Neuronal cell death. Neuron, 1998, 20, 633-647.
    • (1998) Neuron , vol.20 , pp. 633-647
    • Pettmann, B.1    Henderson, C.E.2
  • 3
    • 0025932984 scopus 로고
    • Apoptosis: Mechanisms and roles in pathology
    • Arends, M.J.; Wyllie, A.H. Apoptosis: mechanisms and roles in pathology. Int. Rev. Exp. Pathol., 1991, 32, 223-254.
    • (1991) Int. Rev. Exp. Pathol , vol.32 , pp. 223-254
    • Arends, M.J.1    Wyllie, A.H.2
  • 4
    • 33947623671 scopus 로고    scopus 로고
    • Neuronal life-and-death signaling, apoptosis, and neurodegenerative disorders
    • Mattson, M. P. Neuronal life-and-death signaling, apoptosis, and neurodegenerative disorders. Antioxid. Redox. Signal., 2006, 8, 1997-2006.
    • (2006) Antioxid. Redox. Signal , vol.8 , pp. 1997-2006
    • Mattson, M.P.1
  • 5
    • 33748474961 scopus 로고    scopus 로고
    • Challenges in neuronal apoptosis
    • Jellinger, K.A. Challenges in neuronal apoptosis. Curr. Alzheimer Res., 2006, 3, 377-391.
    • (2006) Curr. Alzheimer Res , vol.3 , pp. 377-391
    • Jellinger, K.A.1
  • 6
    • 0036432029 scopus 로고    scopus 로고
    • Proteasomal inhibition-induced inclusion formation and death in cortical neurons require transcription and ubiquitination
    • Rideout, H.J.; Stefanis, L. Proteasomal inhibition-induced inclusion formation and death in cortical neurons require transcription and ubiquitination. Mol. Cell Neurosci., 2002, 21, 223-238.
    • (2002) Mol. Cell Neurosci , vol.21 , pp. 223-238
    • Rideout, H.J.1    Stefanis, L.2
  • 8
    • 0036229947 scopus 로고    scopus 로고
    • Propargylamines induce antiapoptotic new protein synthesis in serum- and nerve growth factor (NGF)-withdrawn, NGF-differentiated PC-12 cells
    • Tatton, W.G.; Chalmers-Redman, R.M.; Ju, W.J.; Mammen, M.; Carlile, G.W.; Pong, A.W.; Tatton, N.A. Propargylamines induce antiapoptotic new protein synthesis in serum- and nerve growth factor (NGF)-withdrawn, NGF-differentiated PC-12 cells. J. Pharmacol. Exp. Ther., 2002, 301, 753-764.
    • (2002) J. Pharmacol. Exp. Ther , vol.301 , pp. 753-764
    • Tatton, W.G.1    Chalmers-Redman, R.M.2    Ju, W.J.3    Mammen, M.4    Carlile, G.W.5    Pong, A.W.6    Tatton, N.A.7
  • 9
    • 0035900877 scopus 로고    scopus 로고
    • The neuroprotective actions of FK506 binding protein ligands: Neuronal survival is triggered by de novo RNA synthesis, but is independent of inhibition of JNK and calcineurin
    • Klettner, A.; Baumgrass, R.; Zhang, Y.; Fischer, G.; Burger, E.; Herdegen, T.; Mielke, K. The neuroprotective actions of FK506 binding protein ligands: neuronal survival is triggered by de novo RNA synthesis, but is independent of inhibition of JNK and calcineurin. Brain Res. Mol. Brain Res., 2001, 97, 21-31.
    • (2001) Brain Res. Mol. Brain Res , vol.97 , pp. 21-31
    • Klettner, A.1    Baumgrass, R.2    Zhang, Y.3    Fischer, G.4    Burger, E.5    Herdegen, T.6    Mielke, K.7
  • 10
    • 0031031021 scopus 로고    scopus 로고
    • Induction of Bip mRNA upon programmed cell death of differentiated PC12 cells as well as rat sympathetic neurons
    • Aoki, T.; Koike, T.; Nakano, T.; Shibahara, K.; Kondo, S.; Kikuchi, H.; Honjo, T. Induction of Bip mRNA upon programmed cell death of differentiated PC12 cells as well as rat sympathetic neurons. J. Biochem., 1997, 121, 122-127.
    • (1997) J. Biochem , vol.121 , pp. 122-127
    • Aoki, T.1    Koike, T.2    Nakano, T.3    Shibahara, K.4    Kondo, S.5    Kikuchi, H.6    Honjo, T.7
  • 11
    • 0029847052 scopus 로고    scopus 로고
    • Cyanide-induced apoptosis and oxidative stress in differentiated PC12 cells
    • Mills, E.M.; Gunasekar, P.G.; Pavlakovic, G.; Isom, G.E. Cyanide-induced apoptosis and oxidative stress in differentiated PC12 cells. J. Neurochem., 1996, 67, 1039-1046.
    • (1996) J. Neurochem , vol.67 , pp. 1039-1046
    • Mills, E.M.1    Gunasekar, P.G.2    Pavlakovic, G.3    Isom, G.E.4
  • 12
    • 0028296553 scopus 로고
    • Synthesis of specific proteins in trophic factor-deprived neurons undergoing apoptosis
    • Villa, P.; Miehe, M.; Sensenbrenner, M.; Pettmann, B. Synthesis of specific proteins in trophic factor-deprived neurons undergoing apoptosis. J. Neurochem., 1994, 62, 1468-1475.
    • (1994) J. Neurochem , vol.62 , pp. 1468-1475
    • Villa, P.1    Miehe, M.2    Sensenbrenner, M.3    Pettmann, B.4
  • 13
    • 0027320760 scopus 로고
    • A system for characterizing cellular and molecular events in programmed neuronal cell death
    • Pittman, R.N.; Wang, S.; DiBenedetto, A.J.; Mills, J.C. A system for characterizing cellular and molecular events in programmed neuronal cell death. J. Neurosci., 1993, 13, 3669-3680.
    • (1993) J. Neurosci , vol.13 , pp. 3669-3680
    • Pittman, R.N.1    Wang, S.2    Dibenedetto, A.J.3    Mills, J.C.4
  • 14
    • 0027071804 scopus 로고
    • Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons
    • Mesner, P. W.; Winters, T.R.; Green, S.H. Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons. J. Cell Biol., 1992, 119, 1669-1680.
    • (1992) J. Cell Biol , vol.119 , pp. 1669-1680
    • Mesner, P.W.1    Winters, T.R.2    Green, S.H.3
  • 15
    • 0027483920 scopus 로고
    • Induction of apoptosis in cerebellar granule neurons by low potassium: Inhibition of death by insulin-like growth factor I and cAMP
    • D'Mello, S.R.; Galli, C.; Ciotti, T.; Calissano, P. Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP. Proc. Natl. Acad. Sci. U.S.A, 1993, 90, 10989-10993.
    • (1993) Proc. Natl. Acad. Sci. U.S.A , vol.90 , pp. 10989-10993
    • D'Mello, S.R.1    Galli, C.2    Ciotti, T.3    Calissano, P.4
  • 16
    • 0028924891 scopus 로고
    • Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: The involvement of intracellular calcium and RNA synthesis
    • Galli, C.; Meucci, O.; Scorziello, A.; Werge, T.M.; Calissano, P.; Schettini, G. Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis. J. Neurosci., 1995, 15, 1172-1179.
    • (1995) J. Neurosci , vol.15 , pp. 1172-1179
    • Galli, C.1    Meucci, O.2    Scorziello, A.3    Werge, T.M.4    Calissano, P.5    Schettini, G.6
  • 19
    • 71149094100 scopus 로고    scopus 로고
    • Chemokine profiling of Japanese encephalitis virus-infected mouse neuroblastoma cells by microarray and real-time RT-PCR: Implication in neuropathogenesis
    • Gupta, N.; Santhosh, S.R.; Babu, J.P.; Parida, M.M.; Rao, P.V. Chemokine profiling of Japanese encephalitis virus-infected mouse neuroblastoma cells by microarray and real-time RT-PCR: implication in neuropathogenesis. Virus Res., 2010, 147, 107-112.
    • (2010) Virus Res , vol.147 , pp. 107-112
    • Gupta, N.1    Santhosh, S.R.2    Babu, J.P.3    Parida, M.M.4    Rao, P.V.5
  • 24
  • 25
    • 34250705250 scopus 로고    scopus 로고
    • Siva is an apoptosis-selective p53 target gene important for neuronal cell death
    • Jacobs, S.B.; Basak, S.; Murray, J.I.; Pathak, N.; Attardi, L.D. Siva is an apoptosis-selective p53 target gene important for neuronal cell death. Cell Death Differ., 2007, 14, 1374-1385.
    • (2007) Cell Death Differ , vol.14 , pp. 1374-1385
    • Jacobs, S.B.1    Basak, S.2    Murray, J.I.3    Pathak, N.4    Attardi, L.D.5
  • 26
    • 34247880171 scopus 로고    scopus 로고
    • Transcription factor p53 in degenerating spinal cords
    • Eve, D.J.; Dennis, J.S.; Citron, B.A., Transcription factor p53 in degenerating spinal cords. Brain Res., 2007, 1150, 174-181.
    • (2007) Brain Res , vol.1150 , pp. 174-181
    • Eve, D.J.1    Dennis, J.S.2    Citron, B.A.3
  • 27
    • 34248164348 scopus 로고    scopus 로고
    • Microarray analysis of oxidative stress regulated genes in 2918 mesencephalic dopaminergic neuronal cells: Relevance to oxidative damage in Parkinson's disease
    • Anantharam, V.; Lehrmann, E.; Kanthasamy, A.; Yang, Y.; Banerjee, P.; Becker, K.G.; Freed, W.J.; Kanthasamy, A.G. Microarray analysis of oxidative stress regulated genes in 2918 mesencephalic dopaminergic neuronal cells: relevance to oxidative damage in Parkinson's disease. Neurochem. Int., 2007, 50, 834-847.
    • (2007) Neurochem. Int , vol.50 , pp. 834-847
    • Anantharam, V.1    Lehrmann, E.2    Kanthasamy, A.3    Yang, Y.4    Banerjee, P.5    Becker, K.G.6    Freed, W.J.7    Kanthasamy, A.G.8
  • 28
    • 33847371693 scopus 로고    scopus 로고
    • Microarray reveals complement components are regulated in the serum-deprived rat retinal ganglion cell line
    • Khalyfa, A.; Chlon, T.; Qiang, H.; Agarwal, N.; Cooper, N.G. Microarray reveals complement components are regulated in the serum-deprived rat retinal ganglion cell line. Mol. Vis., 2007, 13, 293-308.
    • (2007) Mol. Vis , vol.13 , pp. 293-308
    • Khalyfa, A.1    Chlon, T.2    Qiang, H.3    Agarwal, N.4    Cooper, N.G.5
  • 29
    • 33847660492 scopus 로고    scopus 로고
    • Neuronal apoptosis mediated by inhibition of intracellular cholesterol transport: Microarray and proteomics analyses in cultured murine cortical neurons
    • Koh, C.H.; Peng, Z.F.; Ou, K.; Melendez, A.; Manikandan, J.; Qi, R.Z.; Cheung, N.S. Neuronal apoptosis mediated by inhibition of intracellular cholesterol transport: microarray and proteomics analyses in cultured murine cortical neurons. J. Cell Physiol., 2007, 211, 63-87.
    • (2007) J. Cell Physiol , vol.211 , pp. 63-87
    • Koh, C.H.1    Peng, Z.F.2    Ou, K.3    Melendez, A.4    Manikandan, J.5    Qi, R.Z.6    Cheung, N.S.7
  • 31
    • 33747040344 scopus 로고    scopus 로고
    • U18666A-mediated apoptosis in cultured murine cortical neurons: Role of caspases, calpains and kinases
    • Koh, C.H.; Qi, R.Z.; Qu, D.; Melendez, A.; Manikandan, J.; Bay, B.H.; Duan, W.; Cheung, N.S. U18666A-mediated apoptosis in cultured murine cortical neurons: role of caspases, calpains and kinases. Cell Signal., 2006, 18, 1572-1583.
    • (2006) Cell Signal , vol.18 , pp. 1572-1583
    • Koh, C.H.1    Qi, R.Z.2    Qu, D.3    Melendez, A.4    Manikandan, J.5    Bay, B.H.6    Duan, W.7    Cheung, N.S.8
  • 32
    • 32644443814 scopus 로고    scopus 로고
    • Cell cycle and cell death regulation of neural progenitor cells in the 5-azacytidine (5AzC)-treated developing fetal brain
    • Ueno, M.; Katayama, K.; Yamauchi, H.; Nakayama, H.; Doi, K. Cell cycle and cell death regulation of neural progenitor cells in the 5-azacytidine (5AzC)-treated developing fetal brain. Exp. Neurol., 2006, 198, 154-166.
    • (2006) Exp. Neurol , vol.198 , pp. 154-166
    • Ueno, M.1    Katayama, K.2    Yamauchi, H.3    Nakayama, H.4    Doi, K.5
  • 34
    • 14144251429 scopus 로고    scopus 로고
    • Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis
    • Jayanthi, S.; Deng, X.; Ladenheim, B.; McCoy, M.T.; Cluster, A.; Cai, N.S.; Cadet, J.L. Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis. Proc. Natl. Acad. Sci. U.S.A., 2005, 102, 868-873.
    • (2005) Proc. Natl. Acad. Sci. U.S.A , vol.102 , pp. 868-873
    • Jayanthi, S.1    Deng, X.2    Ladenheim, B.3    McCoy, M.T.4    Cluster, A.5    Cai, N.S.6    Cadet, J.L.7
  • 35
    • 14044270949 scopus 로고    scopus 로고
    • Genes regulated in neurons undergoing transcription-dependent apoptosis belong to signaling pathways rather than the apoptotic machinery
    • Desagher, S.; Severac, D.; Lipkin, A.; Bernis, C.; Ritchie, W.; Le Digarcher, A.; Journot, L. Genes regulated in neurons undergoing transcription-dependent apoptosis belong to signaling pathways rather than the apoptotic machinery. J. Biol. Chem., 2005, 280, 5693-5702.
    • (2005) J. Biol. Chem , vol.280 , pp. 5693-5702
    • Desagher, S.1    Severac, D.2    Lipkin, A.3    Bernis, C.4    Ritchie, W.5    Le Digarcher, A.6    Journot, L.7
  • 37
    • 4544242219 scopus 로고    scopus 로고
    • Coordinated regulation of gene expression by Brn3a in developing sensory ganglia
    • Eng, S.R.; Lanier, J.; Fedtsova, N.; Turner, E.E. Coordinated regulation of gene expression by Brn3a in developing sensory ganglia. Development., 2004, 131, 3859-3870.
    • (2004) Development , vol.131 , pp. 3859-3870
    • Eng, S.R.1    Lanier, J.2    Fedtsova, N.3    Turner, E.E.4
  • 38
    • 0042477717 scopus 로고    scopus 로고
    • Gene expression during ER stress-induced apoptosis in neurons: Induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway
    • Reimertz, C.; Kogel, D.; Rami, A.; Chittenden, T.; Prehn, J.H. Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J. Cell Biol., 2003, 162, 587-597.
    • (2003) J. Cell Biol , vol.162 , pp. 587-597
    • Reimertz, C.1    Kogel, D.2    Rami, A.3    Chittenden, T.4    Prehn, J.H.5
  • 39
    • 0036428639 scopus 로고    scopus 로고
    • Microarray analysis suggests the involvement of proteasomes, lysosomes, and matrix metalloproteinases in the response of motor neurons to root avulsion
    • Hu, J.; Fink, D.; Mata, M. Microarray analysis suggests the involvement of proteasomes, lysosomes, and matrix metalloproteinases in the response of motor neurons to root avulsion. Eur. J. Neurosci., 2002, 16, 1409-1416.
    • (2002) Eur. J. Neurosci , vol.16 , pp. 1409-1416
    • Hu, J.1    Fink, D.2    Mata, M.3
  • 41
    • 0011486518 scopus 로고    scopus 로고
    • Cerebellar granule cells as a model to study mechanisms of neuronal apoptosis or survival in vivo and in vitro
    • Contestabile, A. Cerebellar granule cells as a model to study mechanisms of neuronal apoptosis or survival in vivo and in vitro. Cerebellum, 2002, 1, 41-55.
    • (2002) Cerebellum , vol.1 , pp. 41-55
    • Contestabile, A.1
  • 42
    • 0027495786 scopus 로고
    • In situ labeling of granule cells for apoptosis-associated DNA fragmentation reveals different mechanisms of cell loss in developing cerebellum
    • Wood, K.A.; Dipasquale, B.; Youle, R.J. In situ labeling of granule cells for apoptosis-associated DNA fragmentation reveals different mechanisms of cell loss in developing cerebellum. Neuron., 1993, 11, 621-632.
    • (1993) Neuron , vol.11 , pp. 621-632
    • Wood, K.A.1    Dipasquale, B.2    Youle, R.J.3
  • 43
    • 0032512892 scopus 로고    scopus 로고
    • Immunohistochemical analysis of developmental stage of external granular layer neurons which undergo apoptosis in postnatal rat cerebellum
    • Tanaka, M.; Marunouchi, T. Immunohistochemical analysis of developmental stage of external granular layer neurons which undergo apoptosis in postnatal rat cerebellum. Neurosci. Lett., 1998, 242, 85-88.
    • (1998) Neurosci. Lett , vol.242 , pp. 85-88
    • Tanaka, M.1    Marunouchi, T.2
  • 45
    • 84884676249 scopus 로고    scopus 로고
    • PACAP type I receptor activation promotes cerebellar neuron survival through the cAMP/PKA signaling pathway
    • Campard, P.K.; Crochemore, C.; Rene, F.; Monnier, D.; Koch, B.; Loeffler, J.P. PACAP type I receptor activation promotes cerebellar neuron survival through the cAMP/PKA signaling pathway. DNA Cell Biol., 1997, 16, 323-333.
    • (1997) DNA Cell Biol , vol.16 , pp. 323-333
    • Campard, P.K.1    Crochemore, C.2    Rene, F.3    Monnier, D.4    Koch, B.5    Loeffler, J.P.6
  • 46
    • 58149103328 scopus 로고    scopus 로고
    • Inhibitory effect of PACAP on caspase activity in neuronal apoptosis: A better understanding towards therapeutic applications in neurodegenerative diseases
    • Dejda, A.; Jolivel, V.; Bourgault, S.; Seaborn, T.; Fournier, A.; Vaudry, H.; Vaudry, D. Inhibitory effect of PACAP on caspase activity in neuronal apoptosis: a better understanding towards therapeutic applications in neurodegenerative diseases. J. Mol. Neurosci., 2008, 36, 26-37.
    • (2008) J. Mol. Neurosci , vol.36 , pp. 26-37
    • Dejda, A.1    Jolivel, V.2    Bourgault, S.3    Seaborn, T.4    Fournier, A.5    Vaudry, H.6    Vaudry, D.7
  • 47
    • 0037111405 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide (PACAP) prevents hippocampal neurons from apoptosis by inhibiting JNK/SAPK and p38 signal transduction pathways
    • Dohi, K.; Mizushima, H.; Nakajo, S.; Ohtaki, H.; Matsunaga, S.; Aruga, T.; Shioda, S. Pituitary adenylate cyclase-activating polypeptide (PACAP) prevents hippocampal neurons from apoptosis by inhibiting JNK/SAPK and p38 signal transduction pathways. Regul. Pept., 2002, 109, 83-88.
    • (2002) Regul. Pept , vol.109 , pp. 83-88
    • Dohi, K.1    Mizushima, H.2    Nakajo, S.3    Ohtaki, H.4    Matsunaga, S.5    Aruga, T.6    Shioda, S.7
  • 48
    • 9744245931 scopus 로고    scopus 로고
    • Opposite regulation of the mitochondrial apoptotic pathway by C2-ceramide and PACAP through a MAP-kinase-dependent mechanism in cerebellar granule cells
    • Falluel-Morel, A.; Aubert, N.; Vaudry, D.; Basille, M.; Fontaine, M.; Fournier, A.; Vaudry, H.; Gonzalez, B.J. Opposite regulation of the mitochondrial apoptotic pathway by C2-ceramide and PACAP through a MAP-kinase-dependent mechanism in cerebellar granule cells. J. Neurochem., 2004, 91, 1231-1243.
    • (2004) J. Neurochem , vol.91 , pp. 1231-1243
    • Falluel-Morel, A.1    Aubert, N.2    Vaudry, D.3    Basille, M.4    Fontaine, M.5    Fournier, A.6    Vaudry, H.7    Gonzalez, B.J.8
  • 49
    • 33745747085 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and trophic factor withdrawal activate distinct signaling cascades that induce glycogen synthase kinase-3 beta and a caspase-9-dependent apoptosis in cerebellar granule neurons
    • Brewster, J.L.; Linseman, D.A.; Bouchard, R.J.; Loucks, F.A.; Precht, T.A.; Esch, E.A.; Heidenreich, K.A. Endoplasmic reticulum stress and trophic factor withdrawal activate distinct signaling cascades that induce glycogen synthase kinase-3 beta and a caspase-9-dependent apoptosis in cerebellar granule neurons. Mol. Cell Neurosci., 2006, 32, 242-253.
    • (2006) Mol. Cell Neurosci , vol.32 , pp. 242-253
    • Brewster, J.L.1    Linseman, D.A.2    Bouchard, R.J.3    Loucks, F.A.4    Precht, T.A.5    Esch, E.A.6    Heidenreich, K.A.7
  • 50
    • 14844310312 scopus 로고    scopus 로고
    • Role of the autophagic-lysosomal system on low potassium-induced apoptosis in cultured cerebellar granule cells
    • Canu, N.; Tufi, R.; Serafino, A.L.; Amadoro, G.; Ciotti, M.T.; Calissano, P. Role of the autophagic-lysosomal system on low potassium-induced apoptosis in cultured cerebellar granule cells. J. Neurochem., 2005, 92, 1228-1242.
    • (2005) J. Neurochem , vol.92 , pp. 1228-1242
    • Canu, N.1    Tufi, R.2    Serafino, A.L.3    Amadoro, G.4    Ciotti, M.T.5    Calissano, P.6
  • 51
    • 20444394386 scopus 로고    scopus 로고
    • Inhibition of GSK3beta is a common event in neuroprotection by different survival factors
    • Chin, P.C.; Majdzadeh, N.; D'Mello, S.R. Inhibition of GSK3beta is a common event in neuroprotection by different survival factors. Brain Res. Mol. Brain Res., 2005, 137, 193-201.
    • (2005) Brain Res. Mol. Brain Res , vol.137 , pp. 193-201
    • Chin, P.C.1    Majdzadeh, N.2    D'Mello, S.R.3
  • 52
    • 0031054670 scopus 로고    scopus 로고
    • Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: Possible involvement of PI 3- kinase in IGF-1 signaling
    • D'Mello, S.R.; Borodezt, K.; Soltoff, S.P., Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3- kinase in IGF-1 signaling. J. Neurosci., 1997, 17, 1548-1560.
    • (1997) J. Neurosci , vol.17 , pp. 1548-1560
    • D'Mello, S.R.1    Borodezt, K.2    Soltoff, S.P.3
  • 53
    • 2342509048 scopus 로고    scopus 로고
    • Rescue of TNFalpha-inhibited neuronal cells by IGF-1 involves Akt and c-Jun N-terminal kinases
    • Kenchappa, P.; Yadav, A.; Singh, G.; Nandana, S.; Banerjee, K. Rescue of TNFalpha-inhibited neuronal cells by IGF-1 involves Akt and c-Jun N-terminal kinases. J. Neurosci. Res., 2004, 76, 466-474.
    • (2004) J. Neurosci. Res , vol.76 , pp. 466-474
    • Kenchappa, P.1    Yadav, A.2    Singh, G.3    Nandana, S.4    Banerjee, K.5
  • 54
    • 0035112978 scopus 로고    scopus 로고
    • NF-kappaB is involved in the survival of cerebellar granule neurons: Association of IkappaBbeta [correction of Ikappabeta] phosphorylation with cell survival
    • Koulich, E.; Nguyen, T.; Johnson, K.; Giardina, C.; D'Mello, S. NF-kappaB is involved in the survival of cerebellar granule neurons: association of IkappaBbeta [correction of Ikappabeta] phosphorylation with cell survival. J. Neurochem., 2001, 76, 1188-1198.
    • (2001) J. Neurochem , vol.76 , pp. 1188-1198
    • Koulich, E.1    Nguyen, T.2    Johnson, K.3    Giardina, C.4    D'Mello, S.5
  • 55
    • 0036850972 scopus 로고    scopus 로고
    • Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons
    • Linseman, D.A.; Phelps, R.A.; Bouchard, R.J.; Le, S.S.; Laessig, T.A.; McClure, M.L.; Heidenreich, K.A. Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons. J. Neurosci., 2002, 22, 9287-9297.
    • (2002) J. Neurosci , vol.22 , pp. 9287-9297
    • Linseman, D.A.1    Phelps, R.A.2    Bouchard, R.J.3    Le, S.S.4    Laessig, T.A.5    McClure, M.L.6    Heidenreich, K.A.7
  • 56
    • 1542304449 scopus 로고    scopus 로고
    • High K+ and IGF-1 protect cerebellar granule neurons via distinct signaling pathways
    • Zhong, J.; Deng, J.; Huang, S.; Yang, X.; Lee, W.H. High K+ and IGF-1 protect cerebellar granule neurons via distinct signaling pathways. J. Neurosci. Res., 2004, 75, 794-806.
    • (2004) J. Neurosci. Res , vol.75 , pp. 794-806
    • Zhong, J.1    Deng, J.2    Huang, S.3    Yang, X.4    Lee, W.H.5
  • 57
    • 15244340082 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 inhibits extracellular signal-regulated kinase to promote neuronal survival via the phosphatidylinositol 3-kinase/protein kinase A/c-Raf pathway
    • Subramaniam, S.; Shahani, N.; Strelau, J.; Laliberte, C.; Brandt, R.; Kaplan, D.; Unsicker, K. Insulin-like growth factor 1 inhibits extracellular signal-regulated kinase to promote neuronal survival via the phosphatidylinositol 3-kinase/protein kinase A/c-Raf pathway. J. Neurosci., 2005, 25, 2838-2852.
    • (2005) J. Neurosci , vol.25 , pp. 2838-2852
    • Subramaniam, S.1    Shahani, N.2    Strelau, J.3    Laliberte, C.4    Brandt, R.5    Kaplan, D.6    Unsicker, K.7
  • 58
    • 33746384584 scopus 로고    scopus 로고
    • Cycloheximide treatment to identify components of the transitional transcriptome in PACAP-induced PC12 cell differentiation
    • Ravni, A.; Eiden, L.E.; Vaudry, H.; Gonzalez, B.J.; Vaudry, D. Cycloheximide treatment to identify components of the transitional transcriptome in PACAP-induced PC12 cell differentiation. J. Neurochem., 2006, 98, 1229-1241.
    • (2006) J. Neurochem , vol.98 , pp. 1229-1241
    • Ravni, A.1    Eiden, L.E.2    Vaudry, H.3    Gonzalez, B.J.4    Vaudry, D.5
  • 60
    • 0034806840 scopus 로고    scopus 로고
    • Rapid induction and Ca(2+) influx-mediated suppression of vitamin D3 up- regulated protein 1 (VDUP1) mRNA in cerebellar granule neurons undergoing apoptosis
    • Saitoh, T.; Tanaka, S.; Koike, T. Rapid induction and Ca(2+) influx-mediated suppression of vitamin D3 up- regulated protein 1 (VDUP1) mRNA in cerebellar granule neurons undergoing apoptosis. J. Neurochem., 2001, 78, 1267-1276.
    • (2001) J. Neurochem , vol.78 , pp. 1267-1276
    • Saitoh, T.1    Tanaka, S.2    Koike, T.3
  • 61
    • 34547463578 scopus 로고    scopus 로고
    • IGF-I inhibition of apoptosis is associated with decreased expression of prostate apoptosis response-4
    • Chung, H.; Seo, S.; Moon, M.; Park, S. IGF-I inhibition of apoptosis is associated with decreased expression of prostate apoptosis response-4. J. Endocrinol., 2007, 194, 77-85.
    • (2007) J. Endocrinol , vol.194 , pp. 77-85
    • Chung, H.1    Seo, S.2    Moon, M.3    Park, S.4
  • 62
    • 33748449038 scopus 로고    scopus 로고
    • A genomic approach to investigate neuronal apoptosis
    • Cavallaro, S.; Calissano, P. A genomic approach to investigate neuronal apoptosis. Curr. Alzheimer Res., 2006, 3, 285-296.
    • (2006) Curr. Alzheimer Res , vol.3 , pp. 285-296
    • Cavallaro, S.1    Calissano, P.2
  • 63
    • 35148834244 scopus 로고    scopus 로고
    • Neuronal apoptosis revealed by genomic analysis: Integrating gene expression profiles with functional information
    • Cavallaro, S. Neuronal apoptosis revealed by genomic analysis: integrating gene expression profiles with functional information. Neuroinformatics, 2007, 5, 115-126.
    • (2007) Neuroinformatics , vol.5 , pp. 115-126
    • Cavallaro, S.1
  • 65
    • 0024271044 scopus 로고
    • Effects of gastric inhibitory polypeptide on glucose and lipid metabolism of isolated rat adipocytes
    • Hauner, H.; Glatting, G.; Kaminska, D.; Pfeiffer, E.F. Effects of gastric inhibitory polypeptide on glucose and lipid metabolism of isolated rat adipocytes. Ann. Nutr. Metab, 1988, 32, 282-288.
    • (1988) Ann. Nutr. Metab , vol.32 , pp. 282-288
    • Hauner, H.1    Glatting, G.2    Kaminska, D.3    Pfeiffer, E.F.4
  • 66
    • 0026469553 scopus 로고    scopus 로고
    • Effects of gastric inhibitory polypeptide and glucagon on portal venous and hepatic arterial flow in conscious dogs
    • Kogire, M.; Inoue, K.; Sumi, S.; Doi, R.; Yun, M.; Kaji, H.; Tobe, T. Effects of gastric inhibitory polypeptide and glucagon on portal venous and hepatic arterial flow in conscious dogs. Dig. Dis. Sci., 37, 1666-1670.
    • Dig. Dis. Sci , vol.37 , pp. 1666-1670
    • Kogire, M.1    Inoue, K.2    Sumi, S.3    Doi, R.4    Yun, M.5    Kaji, H.6    Tobe, T.7
  • 68
    • 33644618433 scopus 로고    scopus 로고
    • The biology of incretin hormones
    • Drucker, D.J. The biology of incretin hormones. Cell Metab., 2006, 3, 153-165.
    • (2006) Cell Metab , vol.3 , pp. 153-165
    • Drucker, D.J.1
  • 69
    • 15044354104 scopus 로고    scopus 로고
    • GIP and GLP-1 as incretin hormones: Lessons from single and double incretin receptor knockout mice
    • Hansotia, T.; Drucker, D.J. GIP and GLP-1 as incretin hormones: lessons from single and double incretin receptor knockout mice. Regul. Pept., 2005, 128, 125-134.
    • (2005) Regul. Pept. , vol.128 , pp. 125-134
    • Hansotia, T.1    Drucker, D.J.2
  • 70
    • 12244268666 scopus 로고    scopus 로고
    • On the physiology of GIP and GLP-1
    • Holst, J.J. On the physiology of GIP and GLP-1. Horm. Metab. Res., 2004, 36, 747-754.
    • (2004) Horm. Metab. Res , vol.36 , pp. 747-754
    • Holst, J.J.1
  • 71
    • 0036378574 scopus 로고    scopus 로고
    • Structure-function of the glucagon receptor family of G protein-coupled receptors: The glucagon, GIP, GLP-1, and GLP-2 receptors
    • Brubaker, P.L.; Drucker, D.J. Structure-function of the glucagon receptor family of G protein-coupled receptors: the glucagon, GIP, GLP-1, and GLP-2 receptors. Receptors Channels, 2002, 8, 179-188.
    • (2002) Receptors Channels , vol.8 , pp. 179-188
    • Brubaker, P.L.1    Drucker, D.J.2
  • 72
    • 0242432370 scopus 로고    scopus 로고
    • Cyclic AMP production and insulin releasing activity of synthetic fragment peptides of glucose-dependent insulinotropic polypeptide
    • Gault, V.A.; Harriott, P.; Flatt, P.R.; O'Harte, F.P. Cyclic AMP production and insulin releasing activity of synthetic fragment peptides of glucose-dependent insulinotropic polypeptide. Biosci. Rep., 2002, 22, 523-528.
    • (2002) Biosci. Rep , vol.22 , pp. 523-528
    • Gault, V.A.1    Harriott, P.2    Flatt, P.R.3    O'Harte, F.P.4
  • 74
    • 0029145003 scopus 로고
    • Molecular cloning, functional expression, and signal transduction of the GIP-receptor cloned from a human insulinoma
    • Volz, A.; Goke, R.; Lankat-Buttgereit, B.; Fehmann, H.C.; Bode, H.P.; Goke, B. Molecular cloning, functional expression, and signal transduction of the GIP-receptor cloned from a human insulinoma. FEBS Lett., 1995, 373, 23-29.
    • (1995) FEBS Lett , vol.373 , pp. 23-29
    • Volz, A.1    Goke, R.2    Lankat-Buttgereit, B.3    Fehmann, H.C.4    Bode, H.P.5    Goke, B.6
  • 75
    • 0029082308 scopus 로고
    • Functional expression of the rat pancreatic islet glucose-dependent insulinotropic polypeptide receptor: Ligand binding and intracellular signaling properties
    • Wheeler, M.B.; Gelling, R.W.; McIntosh, C.H.; Georgiou, J.; Brown, J.C.; Pederson, R.A. Functional expression of the rat pancreatic islet glucose-dependent insulinotropic polypeptide receptor: ligand binding and intracellular signaling properties. Endocrinology, 1995, 136, 4629-4639.
    • (1995) Endocrinology , vol.136 , pp. 4629-4639
    • Wheeler, M.B.1    Gelling, R.W.2    McIntosh, C.H.3    Georgiou, J.4    Brown, J.C.5    Pederson, R.A.6
  • 76
    • 0029077296 scopus 로고
    • Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor
    • Gremlich, S.; Porret, A.; Hani, E.H.; Cherif, D.; Vionnet, N.; Froguel, P.; Thorens, B. Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor. Diabetes, 1995, 44, 1202-1208.
    • (1995) Diabetes , vol.44 , pp. 1202-1208
    • Gremlich, S.1    Porret, A.2    Hani, E.H.3    Cherif, D.4    Vionnet, N.5    Froguel, P.6    Thorens, B.7
  • 77
    • 0028207067 scopus 로고
    • Gastric inhibitory polypeptide (GIP) binding sites in rat brain
    • Kaplan, A.M.; Vigna, S.R. Gastric inhibitory polypeptide (GIP) binding sites in rat brain. Peptides, 1994, 15, 297-302.
    • (1994) Peptides , vol.15 , pp. 297-302
    • Kaplan, A.M.1    Vigna, S.R.2
  • 78
    • 0028556401 scopus 로고
    • Hamster gastric inhibitory polypeptide receptor expressed in pancreatic islets and clonal insulin-secreting cells: Its structure and functional properties
    • Yasuda, K.; Inagaki, N.; Yamada, Y.; Kubota, A.; Seino, S.; Seino, Y. Hamster gastric inhibitory polypeptide receptor expressed in pancreatic islets and clonal insulin-secreting cells: its structure and functional properties. Biochem. Biophys. Res. Commun., 1994, 205,1556-1562.
    • (1994) Biochem. Biophys. Res. Commun , vol.205 , pp. 1556-1562
    • Yasuda, K.1    Inagaki, N.2    Yamada, Y.3    Kubota, A.4    Seino, S.5    Seino, Y.6
  • 79
    • 0027136670 scopus 로고    scopus 로고
    • Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain
    • Usdin, T.B.; Mezey, E.; Button, D.C.; Brownstein, M.J.; Bonner, T.I. Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain. Endocrinology, 133, 2861-2870.
    • Endocrinology , vol.133 , pp. 2861-2870
    • Usdin, T.B.1    Mezey, E.2    Button, D.C.3    Brownstein, M.J.4    Bonner, T.I.5
  • 80
    • 20444491588 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression
    • Kim, S.J.; Winter, K.; Nian, C.; Tsuneoka, M.; Koda, Y.; McIntosh, C.H. Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression. J. Biol. Chem., 2005, 280, 22297-22307.
    • (2005) J. Biol. Chem , vol.280 , pp. 22297-22307
    • Kim, S.J.1    Winter, K.2    Nian, C.3    Tsuneoka, M.4    Koda, Y.5    McIntosh, C.H.6
  • 81
    • 12244299202 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide as a regulator of beta cell function and fate
    • Wideman, R.D.; Kieffer, T.J. Glucose-dependent insulinotropic polypeptide as a regulator of beta cell function and fate. Horm. Metab Res., 2004, 36, 782-786.
    • (2004) Horm. Metab Res , vol.36 , pp. 782-786
    • Wideman, R.D.1    Kieffer, T.J.2
  • 82
    • 0036687655 scopus 로고    scopus 로고
    • Mechanisms of mitogenic and anti-apoptotic signaling by glucose-dependent insulinotropic polypeptide in beta(INS-1)-cells
    • Trumper, A.; Trumper, K.; Horsch, D. Mechanisms of mitogenic and anti-apoptotic signaling by glucose-dependent insulinotropic polypeptide in beta(INS-1)-cells. J. Endocrinol., 2002, 174, 233-246.
    • (2002) J. Endocrinol , vol.174 , pp. 233-246
    • Trumper, A.1    Trumper, K.2    Horsch, D.3
  • 84
    • 42249106405 scopus 로고    scopus 로고
    • Protease-resistant glucose-dependent insulinotropic polypeptide agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid
    • Gault, V.A.; Holscher, C. Protease-resistant glucose-dependent insulinotropic polypeptide agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid. J. Neurophysiol., 2008, 99, 1590-1595.
    • (2008) J. Neurophysiol , vol.99 , pp. 1590-1595
    • Gault, V.A.1    Holscher, C.2
  • 85
    • 66049137664 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide (GIP) and its receptor (GIPR): Cellular localization, lesion-affected expression, and impaired regenerative axonal growth
    • Buhren, B.A.; Gasis, M.; Thorens, B.; Muller, H.W.; Bosse, F. Glucose-dependent insulinotropic polypeptide (GIP) and its receptor (GIPR): cellular localization, lesion-affected expression, and impaired regenerative axonal growth. J. Neurosci. Res., 2009, 87, 1858-1870.
    • (2009) J. Neurosci. Res , vol.87 , pp. 1858-1870
    • Buhren, B.A.1    Gasis, M.2    Thorens, B.3    Muller, H.W.4    Bosse, F.5
  • 86
    • 0033951624 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor and neuronal apoptosis
    • Barrett, G.L. The p75 neurotrophin receptor and neuronal apoptosis. Prog. Neurobiol., 2000, 61, 205-229.
    • (2000) Prog. Neurobiol , vol.61 , pp. 205-229
    • Barrett, G.L.1
  • 87
    • 0035367064 scopus 로고    scopus 로고
    • Whole-genome expression analysis: Challenges beyond clustering
    • Altman, R.B.; Raychaudhuri, S. Whole-genome expression analysis: challenges beyond clustering. Curr. Opin. Struct. Biol., 11, 340-347.
    • Curr. Opin. Struct. Biol , vol.11 , pp. 340-347
    • Altman, R.B.1    Raychaudhuri, S.2
  • 88
    • 0036277075 scopus 로고    scopus 로고
    • Functional genomics as applied to mapping transcription regulatory networks
    • Banerjee, N.; Zhang, M.Q. Functional genomics as applied to mapping transcription regulatory networks. Curr. Opin. Microbiol., 5, 313-317.
    • Curr. Opin. Microbiol , vol.5 , pp. 313-317
    • Banerjee, N.1    Zhang, M.Q.2
  • 89
    • 11344276089 scopus 로고    scopus 로고
    • Artificial neural network technologies to identify biomarkers for therapeutic intervention
    • Bicciato, S., Artificial neural network technologies to identify biomarkers for therapeutic intervention. Curr. Opin. Mol. Ther., 2004, 6, 616-623.
    • (2004) Curr. Opin. Mol. Ther , vol.6 , pp. 616-623
    • Bicciato, S.1
  • 90
    • 27144548985 scopus 로고    scopus 로고
    • Towards quantitative biology: Integration of biological information to elucidate disease pathways and to guide drug discovery
    • Fischer, H. P. Towards quantitative biology: integration of biological information to elucidate disease pathways and to guide drug discovery. Biotechnol. Annu. Rev., 2005, 11, 1-68.
    • (2005) Biotechnol. Annu. Rev , vol.11 , pp. 1-68
    • Fischer, H.P.1
  • 92
    • 0037258201 scopus 로고    scopus 로고
    • Use of gene networks from full genome microarray libraries to identify functionally relevant drug-affected genes and gene regulation cascades
    • Savoie, C.J.; Aburatani, S.; Watanabe, S.; Eguchi, Y.; Muta, S.; Imoto, S.; Miyano, S.; Kuhara, S.; Tashiro, K. Use of gene networks from full genome microarray libraries to identify functionally relevant drug-affected genes and gene regulation cascades. DNA Res., 2003, 10, 19-25.
    • (2003) DNA Res , vol.10 , pp. 19-25
    • Savoie, C.J.1    Aburatani, S.2    Watanabe, S.3    Eguchi, Y.4    Muta, S.5    Imoto, S.6    Miyano, S.7    Kuhara, S.8    Tashiro, K.9
  • 94
    • 47349124275 scopus 로고    scopus 로고
    • What does systems biology mean for drug development
    • Schrattenholz, A.; Soskic, V. What does systems biology mean for drug development? Curr. Med. Chem., 2008, 15, 1520-1528.
    • (2008) Curr. Med. Chem , vol.15 , pp. 1520-1528
    • Schrattenholz, A.1    Soskic, V.2
  • 97
    • 65549102777 scopus 로고    scopus 로고
    • Protein-protein interaction databases: Keeping up with growing interactomes
    • Lehne, B.; Schlitt, T. Protein-protein interaction databases: keeping up with growing interactomes. Hum. Genom., 2009, 3, 291-297.
    • (2009) Hum. Genom , vol.3 , pp. 291-297
    • Lehne, B.1    Schlitt, T.2
  • 98
    • 21344473666 scopus 로고    scopus 로고
    • Novel method for generation of signature networks as biomarkers from complex high throughput data
    • Nikolsky, Y.; Ekins, S.; Nikolskaya, T.; Bugrim, A. A novel method for generation of signature networks as biomarkers from complex high throughput data. Toxicol. Lett., 2005, 158, 20-29.
    • (2005) Toxicol. Lett , vol.158 , pp. 20-29
    • Nikolsky, Y.1    Ekins, S.2    Nikolskaya, T.3    Bugrim, A.A.4
  • 99
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar, R.; Domrachev, M.; Lash, A.E. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res., 2002, 30, 207-210.
    • (2002) Nucleic Acids Res , vol.30 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 107
    • 0033982936 scopus 로고    scopus 로고
    • KEGG: Kyoto encyclopedia of genes and genomes
    • Kanehisa, M.; Goto, S. KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res., 2000, 28, 27-30.
    • (2000) Nucleic Acids Res , vol.28 , pp. 27-30
    • Kanehisa, M.1    Goto, S.2
  • 109
    • 75549090213 scopus 로고    scopus 로고
    • KEGG for representation and analysis of molecular networks involving diseases and drugs
    • Kanehisa, M.; Goto, S.; Furumichi, M.; Tanabe, M.; Hirakawa, M. KEGG for representation and analysis of molecular networks involving diseases and drugs. Nucleic Acids Res., 2010, 38, D355-D360.
    • (2010) Nucleic Acids Res , vol.38
    • Kanehisa, M.1    Goto, S.2    Furumichi, M.3    Tanabe, M.4    Hirakawa, M.5
  • 111
    • 67349115359 scopus 로고    scopus 로고
    • Gene expression profiling of TGFbeta2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-beta2 signaling
    • Fuchshofer, R.; Stephan, D.A.; Russell, P.; Tamm, E.R. Gene expression profiling of TGFbeta2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-beta2 signaling. Exp. Eye Res., 2009, 88, 1020-1032.
    • (2009) Exp. Eye Res , vol.88 , pp. 1020-1032
    • Fuchshofer, R.1    Stephan, D.A.2    Russell, P.3    Tamm, E.R.4
  • 112
    • 57349171316 scopus 로고    scopus 로고
    • Gene expression profiling of light-induced retinal degeneration in phototransduction gene knockout mice
    • Krishnan, J.; Chen, J.; Shin, K.J.; Hwang, J.I.; Han, S.U.; Lee, G.; Choi, S. Gene expression profiling of light-induced retinal degeneration in phototransduction gene knockout mice. Exp. Mol. Med., 2008, 40, 495-504.
    • (2008) Exp. Mol. Med , vol.40 , pp. 495-504
    • Krishnan, J.1    Chen, J.2    Shin, K.J.3    Hwang, J.I.4    Han, S.U.5    Lee, G.6    Choi, S.7
  • 116
    • 54249155522 scopus 로고    scopus 로고
    • Network pharmacology: The next paradigm in drug discovery
    • Hopkins, A.L. Network pharmacology: the next paradigm in drug discovery. Nat. Chem. Biol., 2008, 4, 682-690.
    • (2008) Nat. Chem. Biol , vol.4 , pp. 682-690
    • Hopkins, A.L.1
  • 117
    • 0027944481 scopus 로고
    • Development of a method for measuring cell number: Application to CNS primary neuronal cultures
    • Volonte, C.; Ciotti, M.T.; Battistini, L. Development of a method for measuring cell number: application to CNS primary neuronal cultures. Cytometry, 1994, 17, 274-276.
    • (1994) Cytometry , vol.17 , pp. 274-276
    • Volonte, C.1    Ciotti, M.T.2    Battistini, L.3
  • 118
    • 33847209892 scopus 로고    scopus 로고
    • Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis
    • Lederer, C. W.; Torrisi, A.; Pantelidou, M.; Santama, N.; Cavallaro, S. Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis. BMC Genom., 2007, 8, 26.
    • (2007) BMC Genom , vol.8 , pp. 26
    • Lederer, C.W.1    Torrisi, A.2    Pantelidou, M.3    Santama, N.4    Cavallaro, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.