-
1
-
-
3242777669
-
Insulin-degrading enzyme and Alzheimer disease: A genetic association study in the Han Chinese
-
Bian, L., Yang, J. D., Guo, T. W., Sun, Y., Duan, S. W., Chen, W. Y., et al. (2004). Insulin-degrading enzyme and Alzheimer disease: A genetic association study in the Han Chinese. Neurology, 63(2), 241-245.
-
(2004)
Neurology
, vol.63
, Issue.2
, pp. 241-245
-
-
Bian, L.1
Yang, J.D.2
Guo, T.W.3
Sun, Y.4
Duan, S.W.5
Chen, W.Y.6
-
2
-
-
39149086985
-
Presynaptic release probability is increased in hippocampal neurons from ASIC1 knockout mice
-
Cho, J. H., & Askwith, C. C. (2008). Presynaptic release probability is increased in hippocampal neurons from ASIC1 knockout mice. Journal of Neurophysiology, 99(2), 426-441.
-
(2008)
Journal of Neurophysiology
, vol.99
, Issue.2
, pp. 426-441
-
-
Cho, J.H.1
Askwith, C.C.2
-
4
-
-
0034662929
-
BACE2, a beta-secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein
-
Farzan, M., Schnitzler, C. E., Vasilieva, N., Leung, D., & Choe, H. (2000). BACE2, a beta-secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein. Proceedings of the National Academy of Sciences of the United States of America, 97(17), 9712-9717.
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.17
, pp. 9712-9717
-
-
Farzan, M.1
Schnitzler, C.E.2
Vasilieva, N.3
Leung, D.4
Choe, H.5
-
6
-
-
10744232186
-
Mechanisms of Aβ clearance and catabolism
-
Guenette, S. Y. (2003). Mechanisms of Aβ clearance and catabolism. Neuromolecular Medicine, 4(3), 147-160.
-
(2003)
Neuromolecular Medicine
, vol.4
, Issue.3
, pp. 147-160
-
-
Guenette, S.Y.1
-
7
-
-
60249095085
-
An integral approach to the etiopathogenesis of human neurodegenerative diseases (HNDDs) and cancer. Possible therapeutic consequences within the frame of the trophic factor withdrawal syndrome (TFWS)
-
Harguindey, S., Orive, G., Cacabelos, R., Hevia, E. M., de Otazu, R. D., Arranz, J. L., et al. (2008). An integral approach to the etiopathogenesis of human neurodegenerative diseases (HNDDs) and cancer. Possible therapeutic consequences within the frame of the trophic factor withdrawal syndrome (TFWS). Neuropsychiatric Disease and Treatment, 4(6), 1073-1084.
-
(2008)
Neuropsychiatric Disease and Treatment
, vol.4
, Issue.6
, pp. 1073-1084
-
-
Harguindey, S.1
Orive, G.2
Cacabelos, R.3
Hevia, E.M.4
De Otazu, R.D.5
Arranz, J.L.6
-
8
-
-
24944481656
-
The role of pH dynamics and the Na+/H+ an-tiporter in the etiopathogenesis and treatment of cancer. Two faces of the same coin\One single nature
-
Harguindey, S., Orive, G., Luis Pedraz, J., Paradiso, A., & Reshkin, S. J. (2005). The role of pH dynamics and the Na+/H+ an-tiporter in the etiopathogenesis and treatment of cancer. Two faces of the same coin\One single nature. Biochimica et Biophys-ica Acta, 1756(1), 1-24.
-
(2005)
Biochimica et Biophys-ica Acta
, vol.1756
, Issue.1
, pp. 1-24
-
-
Harguindey, S.1
Orive, G.2
Luis Pedraz, J.3
Paradiso, A.4
Reshkin, S.J.5
-
9
-
-
33847119787
-
Growth and trophic factors, pH and the Na+/H+ exchanger in Alzheimer's disease, other neurodegenerative diseases and cancer: New therapeutic possibilities and potential dangers
-
Harguindey, S., Reshkin, S. J., Orive, G., Arranz, J. L., & Anitua, E. (2007). Growth and trophic factors, pH and the Na+/H+ exchanger in Alzheimer's disease, other neurodegenerative diseases and cancer: New therapeutic possibilities and potential dangers. Current Alzheimer Research, 4(1), 53-65.
-
(2007)
Current Alzheimer Research
, vol.4
, Issue.1
, pp. 53-65
-
-
Harguindey, S.1
Reshkin, S.J.2
Orive, G.3
Arranz, J.L.4
Anitua, E.5
-
10
-
-
3042552860
-
Amiloride kills malignant glioma cells independent of its inhibition of the sodium-hydrogen exchanger
-
Hegde, M., Roscoe, J., Cala, P., & Gorin, F. (2004). Amiloride kills malignant glioma cells independent of its inhibition of the sodium-hydrogen exchanger. Journal of Pharmacology and Experimental Therapeutics, 310(1), 67-74.
-
(2004)
Journal of Pharmacology and Experimental Therapeutics
, vol.310
, Issue.1
, pp. 67-74
-
-
Hegde, M.1
Roscoe, J.2
Cala, P.3
Gorin, F.4
-
11
-
-
0033775709
-
Total inactivation of gamma-secretase activity in presenilin-defcient embryonic stem cells
-
Herreman, A., Serneels, L., Annaert, W., Collen, D., Schoonjans, L., & De Strooper, B. (2000). Total inactivation of gamma-secretase activity in presenilin-defcient embryonic stem cells. Nature Cell Biology, 2(7), 461-462.
-
(2000)
Nature Cell Biology
, vol.2
, Issue.7
, pp. 461-462
-
-
Herreman, A.1
Serneels, L.2
Annaert, W.3
Collen, D.4
Schoonjans, L.5
De Strooper, B.6
-
12
-
-
54349098256
-
2+ infux in rat cortical neurons
-
2+ infux in rat cortical neurons. Journal of Pharmacology and Experimental Therapeutics, 327(2), 491-502.
-
(2008)
Journal of Pharmacology and Experimental Therapeutics
, vol.327
, Issue.2
, pp. 491-502
-
-
Herrera, Y.1
Katnik, C.2
Rodriguez, J.D.3
Hall, A.A.4
Willing, A.5
Pennypacker, K.R.6
-
13
-
-
0033382226
-
Identifcation of a novel aspartic protease (Asp 2) as beta-secretase
-
Hussain, I., Powell, D., Howlett, D. R., Tew, D. G., Meek, T. D., Chapman, C., et al. (1999). Identifcation of a novel aspartic protease (Asp 2) as beta-secretase. Molecular and Cellular Neu-rosciences, 14(6), 419-427.
-
(1999)
Molecular and Cellular Neu-rosciences
, vol.14
, Issue.6
, pp. 419-427
-
-
Hussain, I.1
Powell, D.2
Howlett, D.R.3
Tew, D.G.4
Meek, T.D.5
Chapman, C.6
-
14
-
-
0031830218
-
Distinct pH homeostatic features in lymphoblasts from Alzheimer's disease patients
-
Ibarreta, D., Urcelay, E., Parrilla, R., & Ayuso, M. S. (1998). Distinct pH homeostatic features in lymphoblasts from Alzheimer's disease patients. Annals of Neurology, 44(2), 216-222.
-
(1998)
Annals of Neurology
, vol.44
, Issue.2
, pp. 216-222
-
-
Ibarreta, D.1
Urcelay, E.2
Parrilla, R.3
Ayuso, M.S.4
-
15
-
-
0043168130
-
Immunolocalization of the acid-sensing ion channel 2a in the rat cerebellum
-
Jovov, B., Tousson, A., McMahon, L. L., & Benos, D. J. (2003). Immunolocalization of the acid-sensing ion channel 2a in the rat cerebellum. Histochemistry and Cell Biology, 119(6), 437-446.
-
(2003)
Histochemistry and Cell Biology
, vol.119
, Issue.6
, pp. 437-446
-
-
Jovov, B.1
Tousson, A.2
McMahon, L.L.3
Benos, D.J.4
-
16
-
-
0033739497
-
Regulation of the formation of tumor cell pseudopodia by the Na(+)/H(+) exchanger NHE1
-
Lagana, A., Vadnais, J., Le, P. U., Nguyen, T. N., Laprade, R., Nabi, I. R., et al. (2000). Regulation of the formation of tumor cell pseudopodia by the Na(+)/H(+) exchanger NHE1. Journal of Cell Science, 113(Pt. 20), 3649-3662.
-
(2000)
Journal of Cell Science
, vol.113
, Issue.PART 20
, pp. 3649-3662
-
-
Lagana, A.1
Vadnais, J.2
Le, P.U.3
Nguyen, T.N.4
Laprade, R.5
Nabi, I.R.6
-
17
-
-
0033616716
-
Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease
-
Lammich, S., Kojro, E., Postina, R., Gilbert, S., Pfeiffer, R., Jasionowski, M., et al. (1999). Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease. Proceedings of the National Academy of Sciences of the United States of America, 96(7), 3922-3927.
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.7
, pp. 3922-3927
-
-
Lammich, S.1
Kojro, E.2
Postina, R.3
Gilbert, S.4
Pfeiffer, R.5
Jasionowski, M.6
-
18
-
-
0031057837
-
Exploring the etiology of Alzheimer disease using molecular genetics
-
Lendon, C. L., Ashall, F., & Goate, A. M. (1997). Exploring the etiology of Alzheimer disease using molecular genetics. Journal of the American Medical Association, 277(10), 825-831.
-
(1997)
Journal of the American Medical Association
, vol.277
, Issue.10
, pp. 825-831
-
-
Lendon, C.L.1
Ashall, F.2
Goate, A.M.3
-
19
-
-
0034621824
-
Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1
-
Li, Y. M., Xu, M., Lai, M. T., Huang, Q., Castro, J. L., DiMuzio-Mower, J., et al. (2000). Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1. Nature, 405(6787), 689-694.
-
(2000)
Nature
, vol.405
, Issue.6787
, pp. 689-694
-
-
Li, Y.M.1
Xu, M.2
Lai, M.T.3
Huang, Q.4
Castro, J.L.5
Dimuzio-Mower, J.6
-
20
-
-
33947531619
-
Physiological role and regulation of the Na+/H+ exchanger
-
Malo, M. E., & Fliegel, L. (2006). Physiological role and regulation of the Na+/H+ exchanger. Canadian Journal of Physiology and Pharmacology, 84(11), 1081-1095.
-
(2006)
Canadian Journal of Physiology and Pharmacology
, vol.84
, Issue.11
, pp. 1081-1095
-
-
Malo, M.E.1
Fliegel, L.2
-
21
-
-
0030667347
-
Correlation between human platelet cytoplasmic membrane outer leafet fuidity, Na+/H+ exchanger activity and aging
-
Marinho, C. F., Costa-Maia, J., Pinto-de-Barros, J., & Oliveira, C. R. (1997). Correlation between human platelet cytoplasmic membrane outer leafet fuidity, Na+/H+ exchanger activity and aging. European Archives of Psychiatry and Clinical Neuroscience, 247(5), 275-277.
-
(1997)
European Archives of Psychiatry and Clinical Neuroscience
, vol.247
, Issue.5
, pp. 275-277
-
-
Marinho, C.F.1
Costa-Maia, J.2
Pinto-De-Barros, J.3
Oliveira, C.R.4
-
22
-
-
0037144078
-
Abeta 42-induced increase in neprilysin is associated with prevention of amyloid plaque formation in vivo
-
Mohajeri, M. H., Wollmer, M. A., & Nitsch, R. M. (2002). Abeta 42-induced increase in neprilysin is associated with prevention of amyloid plaque formation in vivo. Journal of Biological Chemistry, 277(38), 35460-35465.
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.38
, pp. 35460-35465
-
-
Mohajeri, M.H.1
Wollmer, M.A.2
Nitsch, R.M.3
-
23
-
-
1642499374
-
Properties of proton-gated ion channels in sensory neurons of rats
-
Ostovskaya, O. I., Volkova, T. M., & Kristal, O. A. (2003). Properties of proton-gated ion channels in sensory neurons of rats. Neuro-physiology, 35(2), 90-98.
-
(2003)
Neuro-physiology
, vol.35
, Issue.2
, pp. 90-98
-
-
Ostovskaya, O.I.1
Volkova, T.M.2
Kristal, O.A.3
-
24
-
-
1342347799
-
Alzheimer Disease International's 10/66 Dementia Research Group\One model for action research in developing countries
-
Prince, M., Graham, N., Brodaty, H., Rimmer, E., Varghese, M., Chiu, H., et al. (2004). Alzheimer Disease International's 10/66 Dementia Research Group\One model for action research in developing countries. International Journal of Geriatric Psychiatry, 19(2), 178-181.
-
(2004)
International Journal of Geriatric Psychiatry
, vol.19
, Issue.2
, pp. 178-181
-
-
Prince, M.1
Graham, N.2
Brodaty, H.3
Rimmer, E.4
Varghese, M.5
Chiu, H.6
-
25
-
-
0034058373
-
+ exchange, motility, and invasion induced by serum deprivation
-
+ exchange, motility, and invasion induced by serum deprivation. Journal of Biological Chemistry, 275(8), 5361-5369.
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.8
, pp. 5361-5369
-
-
Reshkin, S.J.1
Bellizzi, A.2
Albarani, V.3
Guerra, L.4
Tommasino, M.5
Paradiso, A.6
-
26
-
-
0034652007
-
Apoptosis of leukemic cells accompanies reduction in intracellular pH after targeted inhibition of the Na(+)/H(+) exchanger
-
Rich, I. N., Worthington-White, D., Garden, O. A., & Musk, P. (2000). Apoptosis of leukemic cells accompanies reduction in intracellular pH after targeted inhibition of the Na(+)/H(+) exchanger. Blood, 95(4), 1427-1434.
-
(2000)
Blood
, vol.95
, Issue.4
, pp. 1427-1434
-
-
Rich, I.N.1
Worthington-White, D.2
Garden, O.A.3
Musk, P.4
-
27
-
-
0029004341
-
Cloning of a gene bearing mis-sense mutations in early-onset familial Alzheimer's disease
-
Sherrington, R., Rogaev, E. I., Liang, Y., Rogaeva, E. A., Levesque, G., Ikeda, M., et al. (1995). Cloning of a gene bearing mis-sense mutations in early-onset familial Alzheimer's disease. Nature, 375(6534), 754-760.
-
(1995)
Nature
, vol.375
, Issue.6534
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
-
28
-
-
0033518251
-
Purifcation and cloning of amyloid precursor protein beta-secretase from human brain
-
Sinha, S., Anderson, J. P., Barbour, R., Basi, G. S., Caccavello, R., Davis, D., et al. (1999). Purifcation and cloning of amyloid precursor protein beta-secretase from human brain. Nature, 402(6761), 537-540.
-
(1999)
Nature
, vol.402
, Issue.6761
, pp. 537-540
-
-
Sinha, S.1
Anderson, J.P.2
Barbour, R.3
Basi, G.S.4
Caccavello, R.5
Davis, D.6
-
29
-
-
0348010388
-
Substrate activation of insulin-degrading enzyme (insulysin). A potential target for drug development
-
Song, E. S., Juliano, M. A., Juliano, L., & Hersh, L. B. (2003). Substrate activation of insulin-degrading enzyme (insulysin). A potential target for drug development. Journal of Biological Chemistry, 278(50), 49789-49794.
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.50
, pp. 49789-49794
-
-
Song, E.S.1
Juliano, M.A.2
Juliano, L.3
Hersh, L.B.4
-
30
-
-
0035033845
-
+ exchanger
-
+ exchanger. Neurobiology of Disease, 8(2), 289-298.
-
(2001)
Neurobiology of Disease
, vol.8
, Issue.2
, pp. 289-298
-
-
Urcelay, E.1
Ibarreta, D.2
Parrilla, R.3
Ayuso, M.S.4
Martin-Requero, A.5
-
31
-
-
0033595706
-
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the trans-membrane aspartic protease BACE
-
Vassar, R., Bennett, B. D., Babu-Khan, S., Kahn, S., Mendiaz, E. A., Denis, P., et al. (1999). Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the trans-membrane aspartic protease BACE. Science, 286(5440), 735-741.
-
(1999)
Science
, vol.286
, Issue.5440
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendiaz, E.A.5
Denis, P.6
-
32
-
-
33646360185
-
Beta-amyloid degradation and alzheimer's disease
-
Wang, D. S., Dickson, D. W., & Malter, J. S. (2006). Beta-Amyloid Degradation and Alzheimer's Disease. Journal of Biomedicine and Biotechnology, 2006(3), 58406.
-
(2006)
Journal of Biomedicine and Biotechnology
, vol.2006
, Issue.3
, pp. 58406
-
-
Wang, D.S.1
Dickson, D.W.2
Malter, J.S.3
-
33
-
-
38649129918
-
Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases
-
Xiong, Z. G., Pignataro, G., Li, M., Chang, S. Y., & Simon, R. P. (2008). Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases. Current Opinion in Pharmacology, 8(1), 25-32.
-
(2008)
Current Opinion in Pharmacology
, vol.8
, Issue.1
, pp. 25-32
-
-
Xiong, Z.G.1
Pignataro, G.2
Li, M.3
Chang, S.Y.4
Simon, R.P.5
-
34
-
-
33747045550
-
Hypoxia and reoxygenation increased BACE1 mRNA and protein levels in human neu-roblastoma SH-SY5Y cells
-
Xue, S., Jia, L., & Jia, J. (2006). Hypoxia and reoxygenation increased BACE1 mRNA and protein levels in human neu-roblastoma SH-SY5Y cells. Neuroscience Letters, 405(3), 231-235.
-
(2006)
Neuroscience Letters
, vol.405
, Issue.3
, pp. 231-235
-
-
Xue, S.1
Jia, L.2
Jia, J.3
-
35
-
-
0033518264
-
Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity
-
Yan, R., Bienkowski, M. J., Shuck, M. E., Miao, H., Tory, M. C., Pauley, A. M., et al. (1999). Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity. Nature, 402(6761), 533-537.
-
(1999)
Nature
, vol.402
, Issue.6761
, pp. 533-537
-
-
Yan, R.1
Bienkowski, M.J.2
Shuck, M.E.3
Miao, H.4
Tory, M.C.5
Pauley, A.M.6
-
36
-
-
0037236622
-
Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease
-
Yang, L. B., Lindholm, K., Yan, R., Citron, M., Xia, W., Yang, X. L., et al. (2003). Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease. Nature Medicine, 9(1), 3-4.
-
(2003)
Nature Medicine
, vol.9
, Issue.1
, pp. 3-4
-
-
Yang, L.B.1
Lindholm, K.2
Yan, R.3
Citron, M.4
Xia, W.5
Yang, X.L.6
-
37
-
-
0038411339
-
Quan-tifcation and distribution of beta-secretase alternative splice variants in the rat and human brain
-
Zohar, O., Cavallaro, S., D'Agata, V., & Alkon, D. L. (2003). Quan-tifcation and distribution of beta-secretase alternative splice variants in the rat and human brain. Brain Research. Molecular Brain Research, 115(1), 63-68.
-
(2003)
Brain Research. Molecular Brain Research
, vol.115
, Issue.1
, pp. 63-68
-
-
Zohar, O.1
Cavallaro, S.2
D'Agata, V.3
Alkon, D.L.4
|