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Volumn 99, Issue 3, 2010, Pages 351-359

Neurochemical alterations in lemon shark (Negaprion brevirostris) brains in association with brevetoxin exposure

Author keywords

Algal blooms; Biotoxins; Neurochemical biomarkers; Neurotoxicology

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); BREVETOXIN; CHOLINESTERASE; MERCURY; METHYLMERCURY; MUSCARINIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SELENIUM;

EID: 77955560720     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2010.05.014     Document Type: Article
Times cited : (24)

References (124)
  • 2
    • 0041909619 scopus 로고    scopus 로고
    • Sensorimotor deficits and increased brain nicotinic acetylcholine receptors following exposure to chlorpyrifos and/or nicotine in rats
    • Abou-Donia M.B., Abdel-Rahman A., Goldstein L.B., Dechkovskaia A.M., Shah D.U., Bullman S.L., Khan W.A. Sensorimotor deficits and increased brain nicotinic acetylcholine receptors following exposure to chlorpyrifos and/or nicotine in rats. Arch. Toxicol. 2003, 77:452-458.
    • (2003) Arch. Toxicol. , vol.77 , pp. 452-458
    • Abou-Donia, M.B.1    Abdel-Rahman, A.2    Goldstein, L.B.3    Dechkovskaia, A.M.4    Shah, D.U.5    Bullman, S.L.6    Khan, W.A.7
  • 3
    • 19044381103 scopus 로고    scopus 로고
    • Effects of inhaled brevetoxins in allergic airways: toxin-allergen interactions and pharmacologic intervention
    • Abraham W.M., Bourdelais A.J., Ahmed A., Serebriakov I., Baden D.G. Effects of inhaled brevetoxins in allergic airways: toxin-allergen interactions and pharmacologic intervention. Environ. Health Perspect. 2005, 113:632-637.
    • (2005) Environ. Health Perspect. , vol.113 , pp. 632-637
    • Abraham, W.M.1    Bourdelais, A.J.2    Ahmed, A.3    Serebriakov, I.4    Baden, D.G.5
  • 4
    • 77955552591 scopus 로고    scopus 로고
    • Preliminary assessment of a nearshore nursery ground for the scalloped hammerhead off the Atlantic coast of Florida
    • Adams D.H., Paperno R. Preliminary assessment of a nearshore nursery ground for the scalloped hammerhead off the Atlantic coast of Florida. American Fisheries Society Symposium, vol. 50 2007, 165-174.
    • (2007) American Fisheries Society Symposium, vol. 50 , pp. 165-174
    • Adams, D.H.1    Paperno, R.2
  • 5
    • 0027481319 scopus 로고
    • Brevetoxin depresses synaptic transmission in guinea pig hippocampal slices
    • Apland J.P., Adler M., Sheridan R.E. Brevetoxin depresses synaptic transmission in guinea pig hippocampal slices. Brain Res. Bull. 1993, 31:201-207.
    • (1993) Brain Res. Bull. , vol.31 , pp. 201-207
    • Apland, J.P.1    Adler, M.2    Sheridan, R.E.3
  • 6
    • 0022971805 scopus 로고
    • Nerve membrane sodium channels as the target site of brevetoxins at neuromuscular junctions
    • Atchison W.D., Luke V.S., Narahashi T., Vogel S.M. Nerve membrane sodium channels as the target site of brevetoxins at neuromuscular junctions. Br. J. Pharmacol. 1986, 89:731-738.
    • (1986) Br. J. Pharmacol. , vol.89 , pp. 731-738
    • Atchison, W.D.1    Luke, V.S.2    Narahashi, T.3    Vogel, S.M.4
  • 8
    • 0020972571 scopus 로고
    • Marine food-borne dinoflagellate toxins
    • Baden D.G. Marine food-borne dinoflagellate toxins. Int. Rev. Cytol. 1983, 82:99-150.
    • (1983) Int. Rev. Cytol. , vol.82 , pp. 99-150
    • Baden, D.G.1
  • 9
    • 0024544737 scopus 로고
    • Brevetoxins: unique polyether dinoflagellate toxins
    • Baden D.G. Brevetoxins: unique polyether dinoflagellate toxins. FASEB J. 1989, 3:1807-1817.
    • (1989) FASEB J. , vol.3 , pp. 1807-1817
    • Baden, D.G.1
  • 10
    • 0021345353 scopus 로고
    • Neuromuscular blocking action of two brevetoxins from the Florida red tide organism Ptychodiscus brevis
    • Baden D.G., Bikhazi G., Decker S.J., Foldes F.F., Leung I. Neuromuscular blocking action of two brevetoxins from the Florida red tide organism Ptychodiscus brevis. Toxicon 1984, 22:75-84.
    • (1984) Toxicon , vol.22 , pp. 75-84
    • Baden, D.G.1    Bikhazi, G.2    Decker, S.J.3    Foldes, F.F.4    Leung, I.5
  • 12
    • 0020025693 scopus 로고
    • Toxicity of two toxins from the Florida red tide marine dinoflagellate, Ptychodiscus brevis
    • Baden D.G., Mende T.J. Toxicity of two toxins from the Florida red tide marine dinoflagellate, Ptychodiscus brevis. Toxicon 1982, 20:457-461.
    • (1982) Toxicon , vol.20 , pp. 457-461
    • Baden, D.G.1    Mende, T.J.2
  • 13
    • 0020432791 scopus 로고
    • Bronchoconstriction caused by Florida red tide toxins
    • Baden D.G., Mende T.J., Bikhazi G., Leung I. Bronchoconstriction caused by Florida red tide toxins. Toxicon 1982, 20:929-932.
    • (1982) Toxicon , vol.20 , pp. 929-932
    • Baden, D.G.1    Mende, T.J.2    Bikhazi, G.3    Leung, I.4
  • 14
    • 34848913435 scopus 로고    scopus 로고
    • Effects of algal-produced neurotoxins on metabolic activity in telencephalon, optic tectum and cerebellum of Atlantic salmon (Salmo salar)
    • Bakke M.J., Horsberg T.E. Effects of algal-produced neurotoxins on metabolic activity in telencephalon, optic tectum and cerebellum of Atlantic salmon (Salmo salar). Aquat. Toxicol. 2007, 85:96-103.
    • (2007) Aquat. Toxicol. , vol.85 , pp. 96-103
    • Bakke, M.J.1    Horsberg, T.E.2
  • 15
    • 34249748862 scopus 로고    scopus 로고
    • Decreased N-methyl-d-aspartic acid (NMDA) receptor levels are associated with mercury exposure in wild and captive mink
    • Basu N., Scheuhammer A.M., Rouvinen-Watt K., Grochowina N., Evans R.D., O'Brien M., Chan H.M. Decreased N-methyl-d-aspartic acid (NMDA) receptor levels are associated with mercury exposure in wild and captive mink. Neurotoxicology 2007, 28:587-593.
    • (2007) Neurotoxicology , vol.28 , pp. 587-593
    • Basu, N.1    Scheuhammer, A.M.2    Rouvinen-Watt, K.3    Grochowina, N.4    Evans, R.D.5    O'Brien, M.6    Chan, H.M.7
  • 17
    • 64349102118 scopus 로고    scopus 로고
    • Pulp and paper mill effluents contain neuroactive substances that potentially disrupt neuroendocrine control of fish reproduction
    • Basu N., Ta C.A., Waye A., Mao J., Hewitt M., Arnason J.T., Trudeau V.L. Pulp and paper mill effluents contain neuroactive substances that potentially disrupt neuroendocrine control of fish reproduction. Environ. Sci. Technol. 2009, 43:1635-1641.
    • (2009) Environ. Sci. Technol. , vol.43 , pp. 1635-1641
    • Basu, N.1    Ta, C.A.2    Waye, A.3    Mao, J.4    Hewitt, M.5    Arnason, J.T.6    Trudeau, V.L.7
  • 18
    • 0032794659 scopus 로고    scopus 로고
    • Uptake, tissue distribution, and excretion of brevetoxin 3 administered to rats by intratracheal instillation
    • Benson J.M., Tischler D.L., Baden D.G. Uptake, tissue distribution, and excretion of brevetoxin 3 administered to rats by intratracheal instillation. J. Toxicol. Environ. Health A 1999, 57:345-355.
    • (1999) J. Toxicol. Environ. Health A , vol.57 , pp. 345-355
    • Benson, J.M.1    Tischler, D.L.2    Baden, D.G.3
  • 19
    • 0033006422 scopus 로고    scopus 로고
    • Brevetoxins cause acute excitotoxicity in primary cultures of rat cerebellar granule neurons
    • Berman F.W., Murray T.F. Brevetoxins cause acute excitotoxicity in primary cultures of rat cerebellar granule neurons. J. Pharmacol. Exp. Ther. 1999, 290:439-444.
    • (1999) J. Pharmacol. Exp. Ther. , vol.290 , pp. 439-444
    • Berman, F.W.1    Murray, T.F.2
  • 21
    • 0018941769 scopus 로고
    • Central respiratory and circulatory effects of Gymnodinium breve toxin in anaesthetized cats
    • Borison H.L., Ellis S., McCarthy L.E. Central respiratory and circulatory effects of Gymnodinium breve toxin in anaesthetized cats. Br. J. Pharmacol. 1980, 70:249-256.
    • (1980) Br. J. Pharmacol. , vol.70 , pp. 249-256
    • Borison, H.L.1    Ellis, S.2    McCarthy, L.E.3
  • 22
    • 0031957397 scopus 로고    scopus 로고
    • Brevetoxicosis in manatees (Trichechus manatus latirostris) from the 1996 epizootic: gross, histologic, and immunohistochemical features
    • Bossart G.D., Baden D.G., Ewing R.Y., Roberts B., Wright S.D. Brevetoxicosis in manatees (Trichechus manatus latirostris) from the 1996 epizootic: gross, histologic, and immunohistochemical features. Toxicol. Pathol. 1998, 26:276-282.
    • (1998) Toxicol. Pathol. , vol.26 , pp. 276-282
    • Bossart, G.D.1    Baden, D.G.2    Ewing, R.Y.3    Roberts, B.4    Wright, S.D.5
  • 23
    • 50949107209 scopus 로고    scopus 로고
    • Comparative study of the use of neuroblastoma cells (Neuro-2a) and neuroblastomaxglioma hybrid cells (NG108-15) for the toxic effect quantification of marine toxins
    • Canete E., Diogene J. Comparative study of the use of neuroblastoma cells (Neuro-2a) and neuroblastomaxglioma hybrid cells (NG108-15) for the toxic effect quantification of marine toxins. Toxicon 2008, 52:541-550.
    • (2008) Toxicon , vol.52 , pp. 541-550
    • Canete, E.1    Diogene, J.2
  • 24
    • 36348956805 scopus 로고    scopus 로고
    • Brevetoxin-induced phosphorylation of Pyk2 and Src in murine neocortical neurons involves distinct signaling pathways
    • Cao Z., George J., Baden D.G., Murray T.F. Brevetoxin-induced phosphorylation of Pyk2 and Src in murine neocortical neurons involves distinct signaling pathways. Brain Res. 2007, 1184:17-27.
    • (2007) Brain Res. , vol.1184 , pp. 17-27
    • Cao, Z.1    George, J.2    Baden, D.G.3    Murray, T.F.4
  • 25
    • 0021824172 scopus 로고
    • Interaction of brevetoxin A with a new receptor site on the sodium channel
    • Catterall W.A., Gainer M. Interaction of brevetoxin A with a new receptor site on the sodium channel. Toxicon 1985, 23:497-504.
    • (1985) Toxicon , vol.23 , pp. 497-504
    • Catterall, W.A.1    Gainer, M.2
  • 26
    • 0019387751 scopus 로고
    • Toxin T4(6) from Ptychodiscus brevis (formerly Gymnodinium breve) enhances activation of voltage-sensitive sodium channels by veratridine
    • Catterall W.A., Risk M. Toxin T4(6) from Ptychodiscus brevis (formerly Gymnodinium breve) enhances activation of voltage-sensitive sodium channels by veratridine. Mol. Pharmacol. 1981, 19:345-348.
    • (1981) Mol. Pharmacol. , vol.19 , pp. 345-348
    • Catterall, W.A.1    Risk, M.2
  • 27
    • 0027131440 scopus 로고
    • Distribution and elimination of ingested brevetoxin (PbTx-3) in rats
    • Cattet M., Geraci J.R. Distribution and elimination of ingested brevetoxin (PbTx-3) in rats. Toxicon 1993, 31:1483-1486.
    • (1993) Toxicon , vol.31 , pp. 1483-1486
    • Cattet, M.1    Geraci, J.R.2
  • 30
    • 0842308208 scopus 로고    scopus 로고
    • Altered brain activity in brevetoxin-exposed bluegill, Lepomis macrochirus, visualized using in vivo 14C 2-deoxyglucose labeling
    • Choich J., Salierno J.D., Silbergeld E.K., Kane A.S. Altered brain activity in brevetoxin-exposed bluegill, Lepomis macrochirus, visualized using in vivo 14C 2-deoxyglucose labeling. Environ. Res. 2004, 94:192-197.
    • (2004) Environ. Res. , vol.94 , pp. 192-197
    • Choich, J.1    Salierno, J.D.2    Silbergeld, E.K.3    Kane, A.S.4
  • 31
    • 0028903333 scopus 로고
    • Excitotoxic activation of the NMDA receptor results in inhibition of calcium/calmodulin kinase II activity in cultured hippocampal neurons
    • Churn S.B., Limbrick D., Sombati S., DeLorenzo R.J. Excitotoxic activation of the NMDA receptor results in inhibition of calcium/calmodulin kinase II activity in cultured hippocampal neurons. J. Neurosci. 1995, 15:3200-3214.
    • (1995) J. Neurosci. , vol.15 , pp. 3200-3214
    • Churn, S.B.1    Limbrick, D.2    Sombati, S.3    DeLorenzo, R.J.4
  • 32
    • 34247230355 scopus 로고    scopus 로고
    • Sublethal effects of the toxic dinoflagellate Karenia brevis on marine copepod behavior
    • Cohen J.H., Tester P.A., Forward R.B. Sublethal effects of the toxic dinoflagellate Karenia brevis on marine copepod behavior. J. Plankton Res. 2007, 29:301-315.
    • (2007) J. Plankton Res. , vol.29 , pp. 301-315
    • Cohen, J.H.1    Tester, P.A.2    Forward, R.B.3
  • 33
    • 0025338354 scopus 로고
    • Excitatory amino acid receptors and synaptic plasticity
    • Collingridge G.L., Singer W. Excitatory amino acid receptors and synaptic plasticity. Trends Pharmacol. Sci. 1990, 11:290-296.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 290-296
    • Collingridge, G.L.1    Singer, W.2
  • 34
    • 0346752077 scopus 로고    scopus 로고
    • The type B brevetoxin (PbTx-3) adversely affects development, cardiovascular function, and survival in Medaka (Oryzias latipes) embryos
    • Colman J.R., Ramsdell J.S. The type B brevetoxin (PbTx-3) adversely affects development, cardiovascular function, and survival in Medaka (Oryzias latipes) embryos. Environ. Health Perspect. 2003, 111:1920-1925.
    • (2003) Environ. Health Perspect. , vol.111 , pp. 1920-1925
    • Colman, J.R.1    Ramsdell, J.S.2
  • 35
    • 0020373758 scopus 로고
    • Renal hemorrhagic necrosis in choline deficiency: prevention of the lesion by treatment with alphamethyldopa
    • Costa R.S., Rossi M.A., Oliveira J.S. Renal hemorrhagic necrosis in choline deficiency: prevention of the lesion by treatment with alphamethyldopa. Arch. Latinoam. Nutr. 1982, 32:682-696.
    • (1982) Arch. Latinoam. Nutr. , vol.32 , pp. 682-696
    • Costa, R.S.1    Rossi, M.A.2    Oliveira, J.S.3
  • 36
    • 2042515864 scopus 로고    scopus 로고
    • Brevetoxin activation of voltage-gated sodium channels regulates Ca dynamics and ERK1/2 phosphorylation in murine neocortical neurons
    • Dravid S.M., Baden D.G., Murray T.F. Brevetoxin activation of voltage-gated sodium channels regulates Ca dynamics and ERK1/2 phosphorylation in murine neocortical neurons. J. Neurochem. 2004, 89:739-749.
    • (2004) J. Neurochem. , vol.89 , pp. 739-749
    • Dravid, S.M.1    Baden, D.G.2    Murray, T.F.3
  • 37
    • 11144285533 scopus 로고    scopus 로고
    • Brevetoxin augments NMDA receptor signaling in murine neocortical neurons
    • Dravid S.M., Baden D.G., Murray T.F. Brevetoxin augments NMDA receptor signaling in murine neocortical neurons. Brain Res. 2005, 1031:30-38.
    • (2005) Brain Res. , vol.1031 , pp. 30-38
    • Dravid, S.M.1    Baden, D.G.2    Murray, T.F.3
  • 38
    • 0242499507 scopus 로고    scopus 로고
    • 2+-permeable AMPA/kainate receptor activation in murine neocortical neurons
    • 2+-permeable AMPA/kainate receptor activation in murine neocortical neurons. Neurosci. Lett. 2003, 351:145-148.
    • (2003) Neurosci. Lett. , vol.351 , pp. 145-148
    • Dravid, S.M.1    Murray, T.F.2
  • 39
    • 0037199344 scopus 로고    scopus 로고
    • Rescue of the acetylcholinesterase knockout mouse by feeding a liquid diet; phenotype of the adult acetylcholinesterase deficient mouse
    • Duysen E.G., Stribley J.A., Fry D.L., Hinrichs S.H., Lockridge O. Rescue of the acetylcholinesterase knockout mouse by feeding a liquid diet; phenotype of the adult acetylcholinesterase deficient mouse. Brain Res. Dev. Brain Res. 2002, 137:43-54.
    • (2002) Brain Res. Dev. Brain Res. , vol.137 , pp. 43-54
    • Duysen, E.G.1    Stribley, J.A.2    Fry, D.L.3    Hinrichs, S.H.4    Lockridge, O.5
  • 40
    • 0026771393 scopus 로고
    • Brevetoxins bind to multiple classes of sites in rat brain synaptosomes
    • Edwards R.A., Trainer V.L., Baden D.G. Brevetoxins bind to multiple classes of sites in rat brain synaptosomes. Brain Res. Mol. Brain Res. 1992, 14:64-70.
    • (1992) Brain Res. Mol. Brain Res. , vol.14 , pp. 64-70
    • Edwards, R.A.1    Trainer, V.L.2    Baden, D.G.3
  • 41
    • 0034669113 scopus 로고    scopus 로고
    • The N-methyl-d-aspartate neurotransmitter receptor is a mammalian brain target for the dinoflagellate Pfiesteria piscicida toxin
    • El-Nabawi A., Quesenberry M., Saito K., Silbergeld E., Vasta G., Eldefrawi A. The N-methyl-d-aspartate neurotransmitter receptor is a mammalian brain target for the dinoflagellate Pfiesteria piscicida toxin. Toxicol. Appl. Pharmacol. 2000, 169:84-93.
    • (2000) Toxicol. Appl. Pharmacol. , vol.169 , pp. 84-93
    • El-Nabawi, A.1    Quesenberry, M.2    Saito, K.3    Silbergeld, E.4    Vasta, G.5    Eldefrawi, A.6
  • 42
    • 0029013930 scopus 로고
    • Muscarinic acetylcholine receptors: signal transduction through multiple effectors
    • Felder C.C. Muscarinic acetylcholine receptors: signal transduction through multiple effectors. FASEB J. 1995, 9:619-625.
    • (1995) FASEB J. , vol.9 , pp. 619-625
    • Felder, C.C.1
  • 43
    • 34548131992 scopus 로고    scopus 로고
    • Brevetoxin exposure in bottlenose dolphins (Tursiops truncatus) associated with Karenia brevis blooms in Sarasota Bay, Florida
    • Fire S.E., Fauquier D., Flewelling L.J., Henry M., Naar J., Pierce R., Well R.S. Brevetoxin exposure in bottlenose dolphins (Tursiops truncatus) associated with Karenia brevis blooms in Sarasota Bay, Florida. Mar. Biol. 2007, 152:827-834.
    • (2007) Mar. Biol. , vol.152 , pp. 827-834
    • Fire, S.E.1    Fauquier, D.2    Flewelling, L.J.3    Henry, M.4    Naar, J.5    Pierce, R.6    Well, R.S.7
  • 46
    • 77955560390 scopus 로고    scopus 로고
    • Vectors of brevetoxins to marine mammals. Dissertation, University of South Florida.
    • Flewelling, L.J., 2008. Vectors of brevetoxins to marine mammals. Dissertation, University of South Florida.
    • (2008)
    • Flewelling, L.J.1
  • 47
    • 77955773508 scopus 로고    scopus 로고
    • Brevetoxins in sharks and rays (Chondrichthyes, Elasmobranchii) from Florida coastal waters
    • doi:10.1007/s00227-010-1463-z
    • Flewelling, L.J., Adams, D.H., Naar, J., Atwood, K.E., Granholm, A.A., O'Dea, S.N., Landsberg, J.H., 2010. Brevetoxins in sharks and rays (Chondrichthyes, Elasmobranchii) from Florida coastal waters. Mar. Biol., doi:10.1007/s00227-010-1463-z.
    • (2010) Mar. Biol.
    • Flewelling, L.J.1    Adams, D.H.2    Naar, J.3    Atwood, K.E.4    Granholm, A.A.5    O'Dea, S.N.6    Landsberg, J.H.7
  • 49
    • 27144500256 scopus 로고    scopus 로고
    • Transcription of the NR1 subunit of the N-methyl-d-aspartate receptor is down-regulated by excitotoxic stimulation and cerebral ischemia
    • Gascon S., Deogracias R., Sobrado M., Roda J.M., Renart J., Rodriguez-Pena A., Diaz-Guerra M. Transcription of the NR1 subunit of the N-methyl-d-aspartate receptor is down-regulated by excitotoxic stimulation and cerebral ischemia. J. Biol. Chem. 2005, 280:35018-35027.
    • (2005) J. Biol. Chem. , vol.280 , pp. 35018-35027
    • Gascon, S.1    Deogracias, R.2    Sobrado, M.3    Roda, J.M.4    Renart, J.5    Rodriguez-Pena, A.6    Diaz-Guerra, M.7
  • 51
    • 63849305126 scopus 로고    scopus 로고
    • Sodium channel activation augments NMDA receptor function and promotes neurite outgrowth in immature cerebrocortical neurons
    • George J., Dravid S.M., Prakash A., Xie J., Peterson J., Jabba S.V., Baden D.G., Murray T.F. Sodium channel activation augments NMDA receptor function and promotes neurite outgrowth in immature cerebrocortical neurons. J. Neurosci. 2009, 29:3288-3301.
    • (2009) J. Neurosci. , vol.29 , pp. 3288-3301
    • George, J.1    Dravid, S.M.2    Prakash, A.3    Xie, J.4    Peterson, J.5    Jabba, S.V.6    Baden, D.G.7    Murray, T.F.8
  • 52
    • 0037020666 scopus 로고    scopus 로고
    • Coupling of extrasynaptic NMDA receptors to a CREB shut-off pathway is developmentally regulated
    • Hardingham G.E., Bading H. Coupling of extrasynaptic NMDA receptors to a CREB shut-off pathway is developmentally regulated. Biochim. Biophys. Acta 2002, 1600:148-153.
    • (2002) Biochim. Biophys. Acta , vol.1600 , pp. 148-153
    • Hardingham, G.E.1    Bading, H.2
  • 53
    • 0011892474 scopus 로고
    • Organophosphorus pesticides
    • Williams & Wilkins, Baltimore, W.A. Hayes (Ed.)
    • Hayes W.A. Organophosphorus pesticides. Pesticide Studies in Man 1982, 385-389. Williams & Wilkins, Baltimore. W.A. Hayes (Ed.).
    • (1982) Pesticide Studies in Man , pp. 385-389
    • Hayes, W.A.1
  • 54
    • 0026002173 scopus 로고
    • Cerebral ischemia decreases the behavioral effects and mortality rate elicited by activation of NMDA receptors in mice
    • Himori N., Moreau J.L., Martin J.R. Cerebral ischemia decreases the behavioral effects and mortality rate elicited by activation of NMDA receptors in mice. Neuropharmacology 1991, 30:1179-1186.
    • (1991) Neuropharmacology , vol.30 , pp. 1179-1186
    • Himori, N.1    Moreau, J.L.2    Martin, J.R.3
  • 55
    • 0021324876 scopus 로고
    • Depolarizing action of a red-tide dinoflagellate brevetoxin on axonal membranes
    • Huang J.M., Wu C.H., Baden D.G. Depolarizing action of a red-tide dinoflagellate brevetoxin on axonal membranes. J. Pharmacol. Exp. Ther. 1984, 229:615-621.
    • (1984) J. Pharmacol. Exp. Ther. , vol.229 , pp. 615-621
    • Huang, J.M.1    Wu, C.H.2    Baden, D.G.3
  • 56
    • 0030271567 scopus 로고    scopus 로고
    • Acute toxicity of synthetic Gymnodinium breve toxin metabolite and its analogues in mice
    • Husain K., Singh R., Kaushik M.P., Gupta A.K. Acute toxicity of synthetic Gymnodinium breve toxin metabolite and its analogues in mice. Ecotoxicol. Environ. Saf. 1996, 35:77-80.
    • (1996) Ecotoxicol. Environ. Saf. , vol.35 , pp. 77-80
    • Husain, K.1    Singh, R.2    Kaushik, M.P.3    Gupta, A.K.4
  • 57
    • 1942532838 scopus 로고    scopus 로고
    • Confirmation of brevetoxin metabolism in cockle, Austrovenus stutchburyi, and greenshell mussel, Perna canaliculus, associated with New Zealand neurotoxic shellfish poisoning, by controlled exposure to Karenia brevis culture
    • Ishida H., Nozawa A., Nukaya H., Rhodes L., McNabb P., Holland P.T., Tsuji K. Confirmation of brevetoxin metabolism in cockle, Austrovenus stutchburyi, and greenshell mussel, Perna canaliculus, associated with New Zealand neurotoxic shellfish poisoning, by controlled exposure to Karenia brevis culture. Toxicon 2004, 43:701-712.
    • (2004) Toxicon , vol.43 , pp. 701-712
    • Ishida, H.1    Nozawa, A.2    Nukaya, H.3    Rhodes, L.4    McNabb, P.5    Holland, P.T.6    Tsuji, K.7
  • 58
    • 0031909499 scopus 로고    scopus 로고
    • Brevetoxin-3 (PbTx-3) and its derivatives modulate single tetrodotoxin-sensitive sodium channels in rat sensory neurons
    • Jeglitsch G., Rein K., Baden D.G., Adams D.J. Brevetoxin-3 (PbTx-3) and its derivatives modulate single tetrodotoxin-sensitive sodium channels in rat sensory neurons. J. Pharmacol. Exp. Ther. 1998, 284:516-525.
    • (1998) J. Pharmacol. Exp. Ther. , vol.284 , pp. 516-525
    • Jeglitsch, G.1    Rein, K.2    Baden, D.G.3    Adams, D.J.4
  • 60
    • 33746495698 scopus 로고    scopus 로고
    • Use of the multispecies freshwater biomonitor to assess behavioral changes of Corophium volutator (Pallas, 1766) (Crustacea, Amphipoda) in response to toxicant exposure in sediment
    • Kirkpatrick A.J., Gerhardt A., Dick J.T., McKenna M., Berges J.A. Use of the multispecies freshwater biomonitor to assess behavioral changes of Corophium volutator (Pallas, 1766) (Crustacea, Amphipoda) in response to toxicant exposure in sediment. Ecotoxicol. Environ. Saf. 2006, 64:298-303.
    • (2006) Ecotoxicol. Environ. Saf. , vol.64 , pp. 298-303
    • Kirkpatrick, A.J.1    Gerhardt, A.2    Dick, J.T.3    McKenna, M.4    Berges, J.A.5
  • 62
    • 0024364142 scopus 로고
    • Comparative study on the enhancement of ischemic tolerance by intracoronary pretreatment with three calcium antagonists in pig hearts
    • Klein H.H., Pich S., Lindert S., Nebendahl K., Kreuzer H. Comparative study on the enhancement of ischemic tolerance by intracoronary pretreatment with three calcium antagonists in pig hearts. Cardiovasc. Drugs Ther. 1989, 2:815-821.
    • (1989) Cardiovasc. Drugs Ther. , vol.2 , pp. 815-821
    • Klein, H.H.1    Pich, S.2    Lindert, S.3    Nebendahl, K.4    Kreuzer, H.5
  • 63
    • 33847135621 scopus 로고    scopus 로고
    • Brain regional acetylcholinesterase activity and muscarinic acetylcholine receptors in rats after repeated administration of cholinesterase inhibitors and its withdrawal
    • Kobayashi H., Suzuki T., Sakamoto M., Hashimoto W., Kashiwada K., Sato I., Akahori F., Satoh T. Brain regional acetylcholinesterase activity and muscarinic acetylcholine receptors in rats after repeated administration of cholinesterase inhibitors and its withdrawal. Toxicol. Appl. Pharmacol. 2007, 219:151-161.
    • (2007) Toxicol. Appl. Pharmacol. , vol.219 , pp. 151-161
    • Kobayashi, H.1    Suzuki, T.2    Sakamoto, M.3    Hashimoto, W.4    Kashiwada, K.5    Sato, I.6    Akahori, F.7    Satoh, T.8
  • 64
    • 61549121088 scopus 로고    scopus 로고
    • Karenia brevis red tides, brevetoxins in the food web, and impacts on natural resources: decadal advancements
    • Landsberg J.H., Flewelling L.J., Naar J. Karenia brevis red tides, brevetoxins in the food web, and impacts on natural resources: decadal advancements. Harmful Algae 2009, 8:598-607.
    • (2009) Harmful Algae , vol.8 , pp. 598-607
    • Landsberg, J.H.1    Flewelling, L.J.2    Naar, J.3
  • 65
    • 0037414734 scopus 로고    scopus 로고
    • Brevetoxin derivatives act as partial agonists at neurotoxin site 5 on the voltage-gated Na+ channel
    • LePage K.T., Baden D.G., Murray T.F. Brevetoxin derivatives act as partial agonists at neurotoxin site 5 on the voltage-gated Na+ channel. Brain Res. 2003, 959:120-127.
    • (2003) Brain Res. , vol.959 , pp. 120-127
    • LePage, K.T.1    Baden, D.G.2    Murray, T.F.3
  • 66
    • 33746528098 scopus 로고    scopus 로고
    • Effects of the dinoflagellate Karenia brevis on larval development in three species of bivalve mollusc from Florida
    • Leverone J.R., Blake N.J., Pierce R.H., Shumway S.E. Effects of the dinoflagellate Karenia brevis on larval development in three species of bivalve mollusc from Florida. Toxicon 2006, 48:75-84.
    • (2006) Toxicon , vol.48 , pp. 75-84
    • Leverone, J.R.1    Blake, N.J.2    Pierce, R.H.3    Shumway, S.E.4
  • 68
    • 36949046857 scopus 로고
    • Isolation and characterization of a toxin from the Florida red tide organism
    • Martin D.F., Chatterjee A.B. Isolation and characterization of a toxin from the Florida red tide organism. Nature 1969, 221:59.
    • (1969) Nature , vol.221 , pp. 59
    • Martin, D.F.1    Chatterjee, A.B.2
  • 70
    • 0036560908 scopus 로고    scopus 로고
    • The origin of the molecular diversity and functional anchoring of cholinesterases
    • Massoulie J. The origin of the molecular diversity and functional anchoring of cholinesterases. Neurosignals 2002, 11:130-143.
    • (2002) Neurosignals , vol.11 , pp. 130-143
    • Massoulie, J.1
  • 71
    • 0023838116 scopus 로고
    • Spatial memory impairment and central muscarinic receptor loss following prolonged treatment with organophosphates
    • McDonald B.E., Costa L.G., Murphy S.D. Spatial memory impairment and central muscarinic receptor loss following prolonged treatment with organophosphates. Toxicol. Lett. 1988, 40:47-56.
    • (1988) Toxicol. Lett. , vol.40 , pp. 47-56
    • McDonald, B.E.1    Costa, L.G.2    Murphy, S.D.3
  • 72
    • 0034065936 scopus 로고    scopus 로고
    • Glutamate as a neurotransmitter in the brain: review of physiology and pathology
    • Meldrum B.S. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J. Nutr. 2000, 130:1007S-1015S.
    • (2000) J. Nutr. , vol.130
    • Meldrum, B.S.1
  • 74
    • 0033588176 scopus 로고    scopus 로고
    • Mice with reduced NMDA receptor expression display behaviors related to schizophrenia
    • Mohn A.R., Gainetdinov R.R., Caron M.G., Koller B.H. Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 1999, 98:427-436.
    • (1999) Cell , vol.98 , pp. 427-436
    • Mohn, A.R.1    Gainetdinov, R.R.2    Caron, M.G.3    Koller, B.H.4
  • 75
    • 0032576783 scopus 로고    scopus 로고
    • Isolation and structure of a new brevetoxin analog, brevetoxin B2, from greenshell mussels from New Zealand
    • Murata K., Satake M., Naoki H., Kaspar H.F., Yasumoto T. Isolation and structure of a new brevetoxin analog, brevetoxin B2, from greenshell mussels from New Zealand. Tetrahedron 1998, 54:735-742.
    • (1998) Tetrahedron , vol.54 , pp. 735-742
    • Murata, K.1    Satake, M.2    Naoki, H.3    Kaspar, H.F.4    Yasumoto, T.5
  • 78
    • 77955558805 scopus 로고    scopus 로고
    • unpublished results. A multiple stressors investigation on mercury and selenium levels in lemon sharks (Negaprion brevirostris) in relation to a harmful red tide event
    • Nam, D.H., Adams, D.H., Reyier, E.A., Basu, N., unpublished results. A multiple stressors investigation on mercury and selenium levels in lemon sharks (Negaprion brevirostris) in relation to a harmful red tide event. Mar. Environ. Res.
    • Mar. Environ. Res.
    • Nam, D.H.1    Adams, D.H.2    Reyier, E.A.3    Basu, N.4
  • 83
    • 52649177139 scopus 로고    scopus 로고
    • Harmful algal toxins of the Florida red tide (Karenia brevis): natural chemical stressors in South Florida coastal ecosystems
    • Pierce R.H., Henry M.S. Harmful algal toxins of the Florida red tide (Karenia brevis): natural chemical stressors in South Florida coastal ecosystems. Ecotoxicology 2008, 17:623-631.
    • (2008) Ecotoxicology , vol.17 , pp. 623-631
    • Pierce, R.H.1    Henry, M.S.2
  • 84
    • 0022901519 scopus 로고
    • Brevetoxins, unique activators of voltage-sensitive sodium channels, bind to specific sites in rat brain synaptosomes
    • Poli M.A., Mende T.J., Baden D.G. Brevetoxins, unique activators of voltage-sensitive sodium channels, bind to specific sites in rat brain synaptosomes. Mol. Pharmacol. 1986, 30:129-135.
    • (1986) Mol. Pharmacol. , vol.30 , pp. 129-135
    • Poli, M.A.1    Mende, T.J.2    Baden, D.G.3
  • 85
    • 0025124775 scopus 로고
    • Distribution and elimination of brevetoxin PbTx-3 in rats
    • Poli M.A., Templeton C.B., Thompson W.L., Hewetson J.F. Distribution and elimination of brevetoxin PbTx-3 in rats. Toxicon 1990, 28:903-910.
    • (1990) Toxicon , vol.28 , pp. 903-910
    • Poli, M.A.1    Templeton, C.B.2    Thompson, W.L.3    Hewetson, J.F.4
  • 86
    • 0442266758 scopus 로고
    • Effects of Gymnodinium breve red tides on fishes and birds: a preliminary report on behavior, anatomy, hematology, and histopathology
    • R.L. Amborski, M.A. Hood, R.R. Miller (Eds.)
    • Quick J.A.J., Henderson G.E. Effects of Gymnodinium breve red tides on fishes and birds: a preliminary report on behavior, anatomy, hematology, and histopathology. Proceedings of the Gulf Coast Regional Symposium on Diseases of Aquatic Animals 1974, 85-113. R.L. Amborski, M.A. Hood, R.R. Miller (Eds.).
    • (1974) Proceedings of the Gulf Coast Regional Symposium on Diseases of Aquatic Animals , pp. 85-113
    • Quick, J.A.J.1    Henderson, G.E.2
  • 87
    • 46749149727 scopus 로고    scopus 로고
    • Brevetoxin forms covalent DNA adducts in rat lung following intratracheal exposure
    • Radwan F.F., Ramsdell J.S. Brevetoxin forms covalent DNA adducts in rat lung following intratracheal exposure. Environ. Health Perspect. 2008, 116:930-936.
    • (2008) Environ. Health Perspect. , vol.116 , pp. 930-936
    • Radwan, F.F.1    Ramsdell, J.S.2
  • 88
    • 0022541184 scopus 로고
    • Neurofibrillary degeneration of cholinergic and noncholinergic neurons of the basal forebrain in Alzheimer's disease
    • Rasool C.G., Svendsen C.N., Selkoe D.J. Neurofibrillary degeneration of cholinergic and noncholinergic neurons of the basal forebrain in Alzheimer's disease. Ann. Neurol. 1986, 20:482-488.
    • (1986) Ann. Neurol. , vol.20 , pp. 482-488
    • Rasool, C.G.1    Svendsen, C.N.2    Selkoe, D.J.3
  • 89
    • 0000708326 scopus 로고
    • Brevetoxin B: chemical modifications, synaptosome binding, and toxicity. An unexpected conformational effect
    • Rein K.S., Baden D.G., Lynn B., Gawley R.W. Brevetoxin B: chemical modifications, synaptosome binding, and toxicity. An unexpected conformational effect. J. Org. Chem. 1994, 59:2101-2106.
    • (1994) J. Org. Chem. , vol.59 , pp. 2101-2106
    • Rein, K.S.1    Baden, D.G.2    Lynn, B.3    Gawley, R.W.4
  • 90
    • 68349128783 scopus 로고    scopus 로고
    • First evidence of a high density nursery ground for the lemon shark, Negaprion brevirostris, near Cape Canaveral, Florida
    • Reyier E.A., Adams D.H., Lowers R.H. First evidence of a high density nursery ground for the lemon shark, Negaprion brevirostris, near Cape Canaveral, Florida. Florida Scientist 2008, 71:134-148.
    • (2008) Florida Scientist , vol.71 , pp. 134-148
    • Reyier, E.A.1    Adams, D.H.2    Lowers, R.H.3
  • 91
    • 0006149119 scopus 로고
    • Purification and chemical studies on a major toxin from Gymnodinium breve
    • Elsevier/North-Holland, New York, D.L. Taylor, H.H. Seliger (Eds.)
    • Risk M., Lin Y.Y., MacFarlane R.D., Ramanujam V.M.S., Smith L.L., Trieff N.M. Purification and chemical studies on a major toxin from Gymnodinium breve. Toxic Dinoflagellate Blooms 1979, 335-344. Elsevier/North-Holland, New York. D.L. Taylor, H.H. Seliger (Eds.).
    • (1979) Toxic Dinoflagellate Blooms , pp. 335-344
    • Risk, M.1    Lin, Y.Y.2    MacFarlane, R.D.3    Ramanujam, V.M.S.4    Smith, L.L.5    Trieff, N.M.6
  • 92
    • 0018584821 scopus 로고
    • High pressure liquid chromatographic separation of two major toxic compounds from Gymnodinium breve davis
    • Risk M., Lin Y.Y., Sadagopa Ramanujam V.M., Smith L.L., Ray S.M., Trieff N.M. High pressure liquid chromatographic separation of two major toxic compounds from Gymnodinium breve davis. J. Chromatogr. Sci. 1979, 17:400-405.
    • (1979) J. Chromatogr. Sci. , vol.17 , pp. 400-405
    • Risk, M.1    Lin, Y.Y.2    Sadagopa Ramanujam, V.M.3    Smith, L.L.4    Ray, S.M.5    Trieff, N.M.6
  • 93
    • 0020402356 scopus 로고
    • Actions of Ptychodiscus brevis red tide toxin on metabolic and transmitter-releasing properties of synaptosomes
    • Risk M., Norris P.J., Coutinho-Netto J., Bradford H.F. Actions of Ptychodiscus brevis red tide toxin on metabolic and transmitter-releasing properties of synaptosomes. J. Neurochem. 1982, 39:1485-1488.
    • (1982) J. Neurochem. , vol.39 , pp. 1485-1488
    • Risk, M.1    Norris, P.J.2    Coutinho-Netto, J.3    Bradford, H.F.4
  • 94
    • 0034143365 scopus 로고    scopus 로고
    • ERKI/II regulation by the muscarinic acetylcholine receptors in neurons
    • Rosenblum K., Futter M., Jones M., Hulme E.C., Bliss T.V. ERKI/II regulation by the muscarinic acetylcholine receptors in neurons. J. Neurosci. 2000, 20:977-985.
    • (2000) J. Neurosci. , vol.20 , pp. 977-985
    • Rosenblum, K.1    Futter, M.2    Jones, M.3    Hulme, E.C.4    Bliss, T.V.5
  • 96
    • 0015313853 scopus 로고
    • Physiological and chemical studies on Gymnodinium breve Davis toxin
    • Sasner J.J., Ikawa M., Thurberg F., Alam M. Physiological and chemical studies on Gymnodinium breve Davis toxin. Toxicon 1972, 10:163-172.
    • (1972) Toxicon , vol.10 , pp. 163-172
    • Sasner, J.J.1    Ikawa, M.2    Thurberg, F.3    Alam, M.4
  • 97
    • 27744466223 scopus 로고    scopus 로고
    • The effect of brevenal on brevetoxin-induced DNA damage in human lymphocytes
    • Sayer A., Hu Q., Bourdelais A.J., Baden D.G., Gibson J.E. The effect of brevenal on brevetoxin-induced DNA damage in human lymphocytes. Arch. Toxicol. 2005, 79:683-688.
    • (2005) Arch. Toxicol. , vol.79 , pp. 683-688
    • Sayer, A.1    Hu, Q.2    Bourdelais, A.J.3    Baden, D.G.4    Gibson, J.E.5
  • 98
    • 33744903108 scopus 로고    scopus 로고
    • The inhibition of CHO-K1-BH4 cell proliferation and induction of chromosomal aberrations by brevetoxins in vitro
    • Sayer A.N., Hu Q., Bourdelais A.J., Baden D.G., Gibson J.E. The inhibition of CHO-K1-BH4 cell proliferation and induction of chromosomal aberrations by brevetoxins in vitro. Food Chem. Toxicol. 2006, 44:1082-1091.
    • (2006) Food Chem. Toxicol. , vol.44 , pp. 1082-1091
    • Sayer, A.N.1    Hu, Q.2    Bourdelais, A.J.3    Baden, D.G.4    Gibson, J.E.5
  • 100
    • 61549112802 scopus 로고    scopus 로고
    • Historical perspective on Karenia brevis red tide research in the Gulf of Mexico
    • Steidinger K.A. Historical perspective on Karenia brevis red tide research in the Gulf of Mexico. Harmful Algae 2009, 8:549-561.
    • (2009) Harmful Algae , vol.8 , pp. 549-561
    • Steidinger, K.A.1
  • 101
    • 0040668951 scopus 로고    scopus 로고
    • Neurotoxic shellfish poisoning due to toxin retention in the clam Chione cancellata
    • Xunta de Galicia and Intergovernmental Oceanographic Commission of UNESCO, B. Reguera, J. Blanco, M.L. Fernandez, T. Wyatt (Eds.)
    • Steidinger K.A., Carlson P., Baden D.G., Rodriguez C., Seagle J. Neurotoxic shellfish poisoning due to toxin retention in the clam Chione cancellata. Harmful Algae 1998, 457-458. Xunta de Galicia and Intergovernmental Oceanographic Commission of UNESCO. B. Reguera, J. Blanco, M.L. Fernandez, T. Wyatt (Eds.).
    • (1998) Harmful Algae , pp. 457-458
    • Steidinger, K.A.1    Carlson, P.2    Baden, D.G.3    Rodriguez, C.4    Seagle, J.5
  • 102
    • 0000352599 scopus 로고    scopus 로고
    • Bloom dynamics and physiology of Gymnodinium breve with emphasis on the Gulf of Mexico
    • Springer, Heidelberg, D.M. Anderson, A.D. Cembella, G.M. Hallegraeff (Eds.)
    • Steidinger K.A., Vargo G.A., Tester P.A., Tomas C.R. Bloom dynamics and physiology of Gymnodinium breve with emphasis on the Gulf of Mexico. Physiological Ecology of Harmful Algal Blooms 1998, 133-153. Springer, Heidelberg. D.M. Anderson, A.D. Cembella, G.M. Hallegraeff (Eds.).
    • (1998) Physiological Ecology of Harmful Algal Blooms , pp. 133-153
    • Steidinger, K.A.1    Vargo, G.A.2    Tester, P.A.3    Tomas, C.R.4
  • 103
    • 0024267923 scopus 로고
    • Florida red tide brevetoxins and binding in fish brain synaptosomes
    • Stuart A.M., Baden D.G. Florida red tide brevetoxins and binding in fish brain synaptosomes. Aquat. Toxicol. 1988, 13:271-280.
    • (1988) Aquat. Toxicol. , vol.13 , pp. 271-280
    • Stuart, A.M.1    Baden, D.G.2
  • 105
  • 106
    • 0024421293 scopus 로고
    • Cardiorespiratory effects of brevetoxin (PbTx-2) in conscious, tethered rats
    • Templeton C.B., Poli M.A., LeClaire R.D. Cardiorespiratory effects of brevetoxin (PbTx-2) in conscious, tethered rats. Toxicon 1989, 27:1043-1049.
    • (1989) Toxicon , vol.27 , pp. 1043-1049
    • Templeton, C.B.1    Poli, M.A.2    LeClaire, R.D.3
  • 107
    • 0024942655 scopus 로고
    • Prophylactic and therapeutic use of an anti-brevetoxin (PbTx-2) antibody in conscious rats
    • Templeton C.B., Poli M.A., Solow R. Prophylactic and therapeutic use of an anti-brevetoxin (PbTx-2) antibody in conscious rats. Toxicon 1989, 27:1389-1395.
    • (1989) Toxicon , vol.27 , pp. 1389-1395
    • Templeton, C.B.1    Poli, M.A.2    Solow, R.3
  • 108
    • 0000802244 scopus 로고    scopus 로고
    • Gymnodinium breve red tide blooms: initiation, transport, and consequences of surface circulation
    • Tester P.A., Steidinger K.A. Gymnodinium breve red tide blooms: initiation, transport, and consequences of surface circulation. Limnol. Oceanogr. 1997, 42:1039-1051.
    • (1997) Limnol. Oceanogr. , vol.42 , pp. 1039-1051
    • Tester, P.A.1    Steidinger, K.A.2
  • 109
    • 0013246011 scopus 로고    scopus 로고
    • Ocean color imagery: what is the minimum detection level for Gymnodinium breve blooms?
    • Xunta de Galicia and Intergovernmental Oceanographic Commission, UNESCO, B. Reguera, J. Blanco, M.L. Fernandez, T. Wyatt (Eds.)
    • Tester P.A., Stumpf R.P., Steidinger K.A. Ocean color imagery: what is the minimum detection level for Gymnodinium breve blooms?. Harmful Algae 1998, 149-151. Xunta de Galicia and Intergovernmental Oceanographic Commission, UNESCO. B. Reguera, J. Blanco, M.L. Fernandez, T. Wyatt (Eds.).
    • (1998) Harmful Algae , pp. 149-151
    • Tester, P.A.1    Stumpf, R.P.2    Steidinger, K.A.3
  • 110
    • 0033979135 scopus 로고    scopus 로고
    • Vectorial transport of toxins from the dinoflagellate Gymnodinium breve through copepods to fish
    • Tester P.A., Turner J.T., Shea D. Vectorial transport of toxins from the dinoflagellate Gymnodinium breve through copepods to fish. J. Plankton Res. 2000, 22:47-61.
    • (2000) J. Plankton Res. , vol.22 , pp. 47-61
    • Tester, P.A.1    Turner, J.T.2    Shea, D.3
  • 111
    • 33746765670 scopus 로고    scopus 로고
    • Uptake, tissue distribution, and excretion of brevetoxin-3 administered to mice by intratracheal instillation
    • Tibbetts B.M., Baden D.G., Benson J.M. Uptake, tissue distribution, and excretion of brevetoxin-3 administered to mice by intratracheal instillation. J. Toxicol. Environ. Health A 2006, 69:1325-1335.
    • (2006) J. Toxicol. Environ. Health A , vol.69 , pp. 1325-1335
    • Tibbetts, B.M.1    Baden, D.G.2    Benson, J.M.3
  • 112
    • 0031563762 scopus 로고    scopus 로고
    • Sodium channel blockade unmasks two temporally distinct mechanisms of striatal dopamine release during hypoxia/hypoglycaemia in vitro
    • Toner C.C., Stamford J.A. Sodium channel blockade unmasks two temporally distinct mechanisms of striatal dopamine release during hypoxia/hypoglycaemia in vitro. Neuroscience 1997, 81:999-1007.
    • (1997) Neuroscience , vol.81 , pp. 999-1007
    • Toner, C.C.1    Stamford, J.A.2
  • 113
    • 0032932631 scopus 로고    scopus 로고
    • High affinity binding of red tide neurotoxins to marine mammal brain
    • Trainer V.L., Baden D.G. High affinity binding of red tide neurotoxins to marine mammal brain. Aquat. Toxicol. 1999, 46:139-148.
    • (1999) Aquat. Toxicol. , vol.46 , pp. 139-148
    • Trainer, V.L.1    Baden, D.G.2
  • 114
    • 0030902159 scopus 로고    scopus 로고
    • Neuroendocrine regulation of gonadotrophin II release and gonadal growth in the goldfish, Carassius auratus
    • Trudeau V.L. Neuroendocrine regulation of gonadotrophin II release and gonadal growth in the goldfish, Carassius auratus. Rev. Reprod. 1997, 2:55-68.
    • (1997) Rev. Reprod. , vol.2 , pp. 55-68
    • Trudeau, V.L.1
  • 115
    • 0025884226 scopus 로고
    • Effects of brevetoxin-B on motor nerve terminals of mouse skeletal muscle
    • Tsai M.C., Chen M.L. Effects of brevetoxin-B on motor nerve terminals of mouse skeletal muscle. Br. J. Pharmacol. 1991, 103:1126-1128.
    • (1991) Br. J. Pharmacol. , vol.103 , pp. 1126-1128
    • Tsai, M.C.1    Chen, M.L.2
  • 116
    • 46349094954 scopus 로고    scopus 로고
    • Effects of in vitro brevetoxin exposure on apoptosis and cellular metabolism in a leukemic T cell line (Jurkat)
    • Walsh C.J., Leggett S.R., Strohbehn K., Pierce R.H., Sleasman J.W. Effects of in vitro brevetoxin exposure on apoptosis and cellular metabolism in a leukemic T cell line (Jurkat). Mar. Drugs 2008, 6:291-307.
    • (2008) Mar. Drugs , vol.6 , pp. 291-307
    • Walsh, C.J.1    Leggett, S.R.2    Strohbehn, K.3    Pierce, R.H.4    Sleasman, J.W.5
  • 117
    • 11144287431 scopus 로고    scopus 로고
    • Effects of environmental stressors on lymphocyte proliferation in Florida manatees, Trichechus manatus latirostris
    • Walsh C.J., Luer C.A., Noyes D.R. Effects of environmental stressors on lymphocyte proliferation in Florida manatees, Trichechus manatus latirostris. Vet. Immunol. Immunopathol. 2005, 103:247-256.
    • (2005) Vet. Immunol. Immunopathol. , vol.103 , pp. 247-256
    • Walsh, C.J.1    Luer, C.A.2    Noyes, D.R.3
  • 118
    • 0028337323 scopus 로고
    • Brevetoxin: tissue distribution and effect on cytochrome P450 enzymes in fish
    • Washburn B.S., Baden D.G., Gassman N.J., Walsh P.J. Brevetoxin: tissue distribution and effect on cytochrome P450 enzymes in fish. Toxicon 1994, 32:799-805.
    • (1994) Toxicon , vol.32 , pp. 799-805
    • Washburn, B.S.1    Baden, D.G.2    Gassman, N.J.3    Walsh, P.J.4
  • 119
    • 0030152508 scopus 로고    scopus 로고
    • Differential effects of brevetoxin and β-naphthoflavone on xenobiotic metabolizing enzymes in striped bass (Morone saxatilis)
    • Washburn B.S., Vines C.A., Baden D.G., Hinton D.E., Walsh P.J. Differential effects of brevetoxin and β-naphthoflavone on xenobiotic metabolizing enzymes in striped bass (Morone saxatilis). Aquat. Toxicol. 1996, 35:1-10.
    • (1996) Aquat. Toxicol. , vol.35 , pp. 1-10
    • Washburn, B.S.1    Vines, C.A.2    Baden, D.G.3    Hinton, D.E.4    Walsh, P.J.5
  • 120
    • 1342302338 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptor knockout mice: novel phenotypes and clinical implications
    • Wess J. Muscarinic acetylcholine receptor knockout mice: novel phenotypes and clinical implications. Annu. Rev. Pharmacol. Toxicol. 2004, 44:423-450.
    • (2004) Annu. Rev. Pharmacol. Toxicol. , vol.44 , pp. 423-450
    • Wess, J.1
  • 123
    • 29844453962 scopus 로고    scopus 로고
    • The role of intracellular sodium in the regulation of NMDA-receptor-mediated channel activity and toxicity
    • Yu X.M. The role of intracellular sodium in the regulation of NMDA-receptor-mediated channel activity and toxicity. Mol. Neurobiol. 2006, 33:63-80.
    • (2006) Mol. Neurobiol. , vol.33 , pp. 63-80
    • Yu, X.M.1


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