Brain regional acetylcholinesterase activity and muscarinic acetylcholine receptors in rats after repeated administration of cholinesterase inhibitors and its withdrawal

Toxicology and Applied Pharmacology

Volumn 219, Issue 2-3, 2007, Pages 151-161

  Kobayashi, Haruo ^a   Suzuki, Tadahiko ^a   Sakamoto, Maki ^b   Hashimoto, Wataru ^c   Kashiwada, Keiko ^a   Sato, Itaru ^a   Akahori, Fumiaki ^d   Satoh, Tetsuo ^e  

^a IWATE UNIVERSITY   (Japan)

^b Kyoritsu Seiyaku Corporation   (Japan)

^c City of Sendai Economic Affairs Bureau Agricultural Promotion Section   (Japan)

^d AZABU UNIVERSITY   (Japan)

^e TOKYO DENTAL COLLEGE   (Japan)

Author keywords

Acetylcholinesterase; Brain; DDVP (dichlorvos); Down regulation; Muscarinic receptors; Oxotremorine; Propoxur; Repeated administration; Withdrawal

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITOR; DICHLORVOS; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC RECEPTOR; N [2 [2 (DIPROPYLAMINOMETHYL) 1 PIPERIDYL]ETHYL] 5,11 DIHYDRO 6 OXO 6H PYRIDO[2,3 B][1,4]BENZODIAZEPINE 11 CARBOXAMIDE; OXOTREMORINE; PIRENZEPINE; PROPOXUR; QUINUCLIDINYL BENZILATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CHOLINERGIC SYSTEM; CONTROLLED STUDY; CORPUS STRIATUM; DOSE TIME EFFECT RELATION; DRUG RECEPTOR BINDING; ENZYME ACTIVITY; ENZYME INHIBITION; HIPPOCAMPUS; MALE; NONHUMAN; RAT; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION;

ACETYLCHOLINESTERASE; ANIMALS; BRAIN; CHOLINESTERASE INHIBITORS; DICHLORVOS; LIGANDS; MALE; PROTEIN BINDING; RATS; RATS, WISTAR; RECEPTORS, MUSCARINIC; SUBSTANCE WITHDRAWAL SYNDROME; TIME FACTORS;

RATTUS;

EID: 33847135621     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2006.11.006     Document Type: Article

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