Occupational exposure to aerosolized brevetoxins during Florida red tide events: Effects on a healthy worker population

Environmental Health Perspectives

Volumn 113, Issue 5, 2005, Pages 644-649

  Backer, Lorraine C ^a   Kirkpatrick, Barbara ^b   Fleming, Lora E ^c   Cheng, Yung Sung ^d   Pierce, Richard ^c   Bean, Judy A ^e   Clark, Richard ^f   Johnson, David ^f   Wanner, Adam ^c   Tamer, Robert ^e   Zhou, Yue ^d   Baden, Daniel G ^g  

^a NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

^b MOTE MARINE LABORATORY   (United States)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^d LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^e CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^f FLORIDA DEPARTMENT OF HEALTH   (United States)

^g UNIVERSITY OF NORTH CAROLINA WILMINGTON   (United States)

Author keywords

Aerosol; Brevetoxins; Karenia brevis; Lifeguards; Pulmonary function; Red tide; Spirometry

Indexed keywords

BREVETOXIN; SEA WATER;

ADULT; AIR SAMPLING; ARTICLE; CONTROLLED STUDY; DINOFLAGELLATE; EXERCISE; FEMALE; HUMAN; LUNG FUNCTION; MALE; NORMAL HUMAN; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; RED TIDE; RESPIRATORY TRACT DISEASE; SELF REPORT; SHELLFISH POISONING; SPIROMETRY; WATER SAMPLING; WORKER;

ADOLESCENT; ADULT; ANIMALS; DINOFLAGELLIDA; EXERCISE; FEMALE; FLORIDA; HUMANS; INHALATION EXPOSURE; MALE; MARINE TOXINS; OCCUPATIONAL EXPOSURE; OXOCINS; RECREATION; RESPIRATORY TRACT DISEASES; SEAWATER; SWIMMING;

DINOPHYCEAE; GYMNODINIUM; KARENIA BREVIS;

EID: 21044439027     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.7502     Document Type: Article

References (17)

1. Abraham WM, Bourdelais A, Sabater JR, Ahmed A, Lee TA, Serebriakov I, et al. 2005. Airway responses to aerosolized brevetoxins in an animal model of asthma. Am J Respir Crit Care Med 171:26-34.
2. American Thoracic Society. 1991. Lung function testing: selection of reference values and interpretive strategies. Am Rev Respir Dis 144:1202-1218.
3. American Thoracic Society. 1995. Standardization of spirometry - 1994 update. Am J Respir Crit Care Med 152:1107-1136.
4. Backer LC, Fleming LE, Rowan A, Cheng Y-S, Benson J, Pierce RH, et al. 2003. Recreational exposure to aerosolized brevetoxins during Florida red tide events. Harmful Algae 2:19-28.
5. Cheng YS, Villareal TA, Shou Y, Gao J, Pierce RH, Wetzel D, et al. 2005a. Characterization of red tide aerosol on the Texas coast. Harmful Algae 4:87-94.
6. Cheng YS, Zhou Y, Irvin CM, Pierce RH, Naar J, Backer LC, et al. 2005b. Characterization of marine aerosol for assessment of human exposure to brevetoxins. Environ Health Perspect 113:638-643.
7. Fleming LE, Kirkpatrick B, Backer LC, Bean JA, Wanner A, Dalpra D, et al. 2005. Initial evaluation of the effects of aerosolized Florida red tide toxins (brevetoxins) in persons with asthma. Environ Health Perspect 113:650-657.
8. Hemmert W. 1974. The public health implications of Gynmodimium breve red tides, a review of the literature and recent events. In: Proceedings of the First International Conference on Toxic Dinoflagellate Blooms, 4-6 November 1974, Boston, MA. Wakefield, MA:Massachusetts Technical Foundation, 489-497.
9. Kirkpatrick B, Hautamaki R, Kane T, Henry M. 2001. A pilot study to explore the occupational exposure to Gymnodinium breve toxin and pulmonary function. In: Harmful Algal Blooms 2000. Proceedings of the 9th International Conference on Harmful Algal Blooms, 7-11 February 2000, Hobart, Australia (Hallegraeff GM, Blackburn SI, Bloch CJ, Lewis RJ, eds). Paris:UNESCO, 447-450.
10. Kirkpatrick MB, Sheppard D, Nadel JA, Boushey HA. 1982. Effect of oronasal breathing route on sulfur dioxide induced bronchoconstriction in exercising asthmatic subjects. Am Rev Respir Dis 125:627-631.
11. Kleinbaum DG, Kupper LL, Morgenstern H. 1982. Epidemiologic Research. New York:Van Nostrand Reinhold, 388-396.
12. Naar J, Bourdelais A, Tomas C, Kubanek J, Whitney P, Fleweling L, et al. 2002. Competitive ELISA to detect brevetoxins from Karenia brevis (formerly Gymnodinium breve) in seawater, shellfish, and mammalian body fluid. Environ Health Perspect 110:179-185.
13. NIOSH. 1997. NIOSH Spirometry Training Guide. Morgantown, WV:National Institute for Occupational Safety and Health.
14. Pierce RH, Henry MS, Blum PC, Hamel SL, Kirkpatrick B, Cheng Y-S, et al. In press. Brevetoxin composition in water and marine aerosol along a Florida beach: assessing potential human exposure to marine biotoxins. Harmful Algae.
15. Pierce RH, Henry MS, Blum PC, Lyons J, Cheng Y-S, Yazzie D, et al. 2003. Brevetoxin concentrations in marine aerosol: human exposure levels during a K. brevis harmful algal bloom. Bull Environ Contam Toxicol 70:161-165.
16. Scanlon CL, Wilkins RL, Stoller JK. 1999. Egan's Fundamentals of Respiratory Care. 7th ed. St. Louis:Mosby, 391.
17. Wells JH, Lerner MR, Martin DF, Strecher RA, Lockey RF. 1984. The effects of respiratory exposure to red tide toxin on airway resistance in conscious guinea pigs [Abstract]. J Allergy Clin Immunol 73:128.