GABA acts as a ligand chaperone in the early secretory pathway to promote cell surface expression of GABAA receptors

Brain Research

Volumn 1346, Issue , 2010, Pages 1-13

  Eshaq, Randa S ^a   Stahl, Letha D ^a   Stone II, Randolph ^a   Smith, Sheryl S ^b   Robinson, Lucy C ^a   Leidenheimer, Nancy J ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b SUNY Downstate Medical Center   (United States)

Author keywords

Aminobutyric acid; Endoplasmic reticulum; GABA transporter; GABAA receptor; Glutamic acid decarboxylase; Ligand chaperone; Secretory pathway

Indexed keywords

1 [2 (BENZHYDRYLIDENEAMINOOXY)ETHYL] 1,2,5,6 TETRAHYDRO 3 PYRIDINECARBOXYLIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID CARRIER; BICUCULLINE; BREFELDIN A; CHAPERONE; GLUTAMATE DECARBOXYLASE 67; RECOMBINANT RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; CELL SURFACE RECEPTOR; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 1; LIGAND;

ANIMAL CELL; ARTICLE; CELL STRAIN HEK293; CELL SURFACE; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTRACELLULAR MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SECRETORY PATHWAY; BIOSYNTHESIS; DRUG EFFECTS; ENDOPLASMIC RETICULUM; FLOW CYTOMETRY; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY;

BICUCULLINE; BREFELDIN A; ENDOPLASMIC RETICULUM; FLOW CYTOMETRY; GABA ANTAGONISTS; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GAMMA-AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE; HUMANS; LIGANDS; MOLECULAR CHAPERONES; MUTATION; RECEPTORS, CELL SURFACE; RECEPTORS, GABA-A; GABA-A RECEPTOR ANTAGONISTS;

EID: 77955509085     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.05.030     Document Type: Article

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