A GABAA receptor mutation linked to human epilepsy (γ2R43Q) impairs cell surface expression of αβγ receptors

Journal of Biological Chemistry

Volumn 279, Issue 45, 2004, Pages 47034-47039

  Sancar, Feyza ^a   Czajkowski, Cynthia ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; CONFORMATIONS; DISEASES; FLUORESCENCE; IMMUNOLOGY; ORGANIC ACIDS; PROTEINS; PURIFICATION;

ARGANINE; IMMUNOBLOTTING; RADIOLIGAND BINDING;

CELLS;

4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE DERIVATIVE; BENZODIAZEPINEFLUNITRAZEPAM; RADIOLIGAND; UNCLASSIFIED DRUG; ARGININE; COMPLEMENTARY DNA; FLUNITRAZEPAM; GLUTAMINE;

ARTICLE; BINDING AFFINITY; BIOTINYLATION; CELL LINE; CELL SURFACE; EPILEPSY; FIBROBLAST CULTURE; GENE MUTATION; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; KIDNEY CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURIFICATION; WILD TYPE; BINDING SITE; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; FLUORESCENCE MICROSCOPY; GENETICS; HUMAN; IC 50; KINETICS; METABOLISM; MUTATION; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; RADIOASSAY; TIME; WESTERN BLOTTING;

ALLOSTERIC SITE; ARGININE; BINDING SITES; BIOTINYLATION; BLOTTING, WESTERN; CELL LINE; CELL MEMBRANE; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; EPILEPSY; FLUNITRAZEPAM; GLUTAMINE; HUMANS; IMMUNOBLOTTING; INHIBITORY CONCENTRATION 50; KINETICS; MICROSCOPY, FLUORESCENCE; MODELS, MOLECULAR; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RADIOLIGAND ASSAY; RECEPTORS, GABA-A; TIME FACTORS;

EID: 8744241623     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M403388200     Document Type: Article

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