Folding efficiency is rate-limiting in dopamine D4 receptor biogenesis

Journal of Biological Chemistry

Volumn 280, Issue 19, 2005, Pages 19350-19357

  Van Craenenbroeck, Kathleen ^a   Clark, Stewart D ^a   Cox, Michael J ^a   Oak, James N ^a   Liu, Fang ^a   Van Tol, Hubert H M ^a,b  

^a CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; DEGRADATION; SENSITIVITY ANALYSIS;

CHAPERON; DOPAMINE; LIGANDS;

PROTEINS;

BUTACLAMOL; CHAPERONE; CLOZAPINE; DOMPERIDONE; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE 4 RECEPTOR; G PROTEIN COUPLED RECEPTOR; HALOPERIDOL; LIGAND; NEUROLEPTIC AGENT; PROTEASOME; QUINPIROLE; ATP DEPENDENT 26S PROTEASE; DNA; DRD4 PROTEIN, HUMAN;

ARTICLE; ATTENTION DEFICIT DISORDER; COGNITION; CONTROLLED STUDY; DOPAMINE RELEASE; ENDOPLASMIC RETICULUM; ENZYME DEGRADATION; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; LOCOMOTION; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STABILITY; RECEPTIVE FIELD; RECEPTOR UPREGULATION; REWARD; SENSITIVITY ANALYSIS; ANIMAL; CELL LINE; CHEMISTRY; CHO CELL; CONFOCAL MICROSCOPY; DOSE RESPONSE; FLUORESCENCE MICROSCOPY; GENETIC TRANSCRIPTION; GLYCOSYLATION; HAMSTER; METABOLISM; MUTATION; NORTHERN BLOTTING; PROTEIN SYNTHESIS; PROTEIN TERTIARY STRUCTURE; TIME; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTIPSYCHOTIC AGENTS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL LINE; CHO CELLS; CRICETINAE; DNA; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; GLYCOSYLATION; HUMANS; LIGANDS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MOLECULAR CHAPERONES; MUTATION; POLYMORPHISM, GENETIC; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BIOSYNTHESIS; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D4; TIME FACTORS; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 21444448611     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M414043200     Document Type: Article

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