Isoalvaxanthone inhibits colon cancer cell proliferation, migration and invasion through inactivating Rac1 and AP-1

International Journal of Cancer

Volumn 127, Issue 5, 2010, Pages 1220-1229

  Wang, Lei ^a   Kuang, Lisha ^a   Pan, Xinhua ^a   Liu, Junchen ^a   Wang, Qian ^a   Du, Bing ^a   Li, Dali ^a   Luo, Jian ^a   Liu, Mingyao ^a   Hou, Aijun ^b   Qian, Min ^a  

^a EAST CHINA NORMAL UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

AP 1; Invasion; Isoalvaxanthone; MMP 2; Rac1

Indexed keywords

GELATINASE A; GUANOSINE TRIPHOSPHATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOALVAXANTHONE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN CDC42; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE; LUCIFERASE; RAC1 PROTEIN, HUMAN;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; METASTASIS; PRIORITY JOURNAL; CANCER INVASION; CELL MOTION; CHEMISTRY; COLON TUMOR; DRUG ANTAGONISM; FLUORESCENT ANTIBODY TECHNIQUE; GEL MOBILITY SHIFT ASSAY; ISOLATION AND PURIFICATION; MEDICINAL PLANT; METABOLISM; MORACEAE; PATHOLOGY; PLANT ROOT; PSEUDOPODIUM; TUMOR CELL LINE; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; COLONIC NEOPLASMS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; LUCIFERASES; MORACEAE; NEOPLASM INVASIVENESS; NF-KAPPA B; PLANT ROOTS; PLANTS, MEDICINAL; PSEUDOPODIA; RAC1 GTP-BINDING PROTEIN; TRANSCRIPTION FACTOR AP-1; XANTHONES;

EID: 77955487713     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25119     Document Type: Article

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