Cudratricusxanthone A isolated from the root bark of Cudrania tricuspidata inhibits the proliferation of vascular smooth muscle cells through the suppression of PDGF-receptor beta tyrosine kinase

Biological and Pharmaceutical Bulletin

Volumn 30, Issue 4, 2007, Pages 805-809

  Kim, Tack Joong ^a   Han, Hyeong Jun ^a   Hong, Seong Su ^a   Hwang, Ji Hye ^a   Hwang, Bang Yeon ^a   Yoo, Hwan Soo ^a   Jin, Yong Ri ^a   Lee, Jung Jin ^a   Yu, Ji Yeon ^a   Lee, Kwang Ho ^b   Kang, Byoung Won ^c   Yun, Yeo Pyo ^a  

^a Chungbuk National University   (South Korea)

^b Konkuk University   (South Korea)

^c Dong Eui University   (South Korea)

Author keywords

Cardiovascular disease; Cudrania tricuspidata; Cudratricusxanthone A; Platelet derived growth factor; Vascular smooth muscle cell

Indexed keywords

CUDRANIA TRICUSPIDATA EXTRACT; CUDRATRICUSXANTHONE A; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASE C; PLANT EXTRACT; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN TYROSINE KINASE; RAS PROTEIN; THYMIDINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ATHEROSCLEROSIS; BARK; CARDIOVASCULAR DISEASE; CELL STRUCTURE; CONTROLLED STUDY; CUDRANIA TRICUSPIDATA; DNA SYNTHESIS; DRUG MECHANISM; DRUG STRUCTURE; LIVER PROTECTION; MORACEAE; NONHUMAN; RAT; RESTENOSIS; SMOOTH MUSCLE FIBER; TRANSLUMINAL CORONARY ANGIOPLASTY; WESTERN BLOTTING;

ANIMALS; AORTA; CELL PROLIFERATION; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; DOSE-RESPONSE RELATIONSHIP, DRUG; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE; MORACEAE; MUSCLE, SMOOTH, VASCULAR; PLANT BARK; PLANT ROOTS; PLATELET-DERIVED GROWTH FACTOR; RATS; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; TIME FACTORS; XANTHONES;

EID: 34147126558     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.30.805     Document Type: Article

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