-
1
-
-
17744393464
-
Treatment of glomerulonephritis: will we ever have options other than steroids and cytotoxics?
-
Javaid B., Quigg R.J. Treatment of glomerulonephritis: will we ever have options other than steroids and cytotoxics?. Kidney Int. 2005, 67:1692-1703.
-
(2005)
Kidney Int.
, vol.67
, pp. 1692-1703
-
-
Javaid, B.1
Quigg, R.J.2
-
2
-
-
35948929764
-
Role of T cells and dendritic cells in glomerular immunopathology
-
Kurts C., et al. Role of T cells and dendritic cells in glomerular immunopathology. Semin. Immunopathol. 2007, 29:317-335.
-
(2007)
Semin. Immunopathol.
, vol.29
, pp. 317-335
-
-
Kurts, C.1
-
3
-
-
35948956955
-
B cells in glomerulonephritis: focus on lupus nephritis
-
Clatworthy M.R., Smith K.G. B cells in glomerulonephritis: focus on lupus nephritis. Semin. Immunopathol. 2007, 29:337-353.
-
(2007)
Semin. Immunopathol.
, vol.29
, pp. 337-353
-
-
Clatworthy, M.R.1
Smith, K.G.2
-
4
-
-
69549106587
-
Pathogenesis of kidney disease in systemic lupus erythematosus
-
Bagavant H., Fu S.M. Pathogenesis of kidney disease in systemic lupus erythematosus. Curr. Opin. Rheumatol. 2009, 21:489-494.
-
(2009)
Curr. Opin. Rheumatol.
, vol.21
, pp. 489-494
-
-
Bagavant, H.1
Fu, S.M.2
-
7
-
-
0019194907
-
The polymorphonuclear neutrophil (PMN) immunohistological technique: detection of immune complexes bound to the PMN membrane in acute poststreptococcal and lupus nephritis
-
Camussi G., et al. The polymorphonuclear neutrophil (PMN) immunohistological technique: detection of immune complexes bound to the PMN membrane in acute poststreptococcal and lupus nephritis. Clin. Nephrol. 1980, 14:280-287.
-
(1980)
Clin. Nephrol.
, vol.14
, pp. 280-287
-
-
Camussi, G.1
-
8
-
-
33646680302
-
Expression of the chemokine receptor CXCR1 in human glomerular diseases
-
Segerer S., et al. Expression of the chemokine receptor CXCR1 in human glomerular diseases. Kidney Int. 2006, 69:1765-1773.
-
(2006)
Kidney Int.
, vol.69
, pp. 1765-1773
-
-
Segerer, S.1
-
9
-
-
0023156194
-
Leukocyte analysis using monoclonal antibodies in human glomerulonephritis
-
Hooke D.H., et al. Leukocyte analysis using monoclonal antibodies in human glomerulonephritis. Kidney Int. 1987, 31:964-972.
-
(1987)
Kidney Int.
, vol.31
, pp. 964-972
-
-
Hooke, D.H.1
-
10
-
-
67650382084
-
An update on acute postinfectious glomerulonephritis worldwide
-
Kanjanabuch T., et al. An update on acute postinfectious glomerulonephritis worldwide. Nat. Rev. Nephrol. 2009, 5:259-269.
-
(2009)
Nat. Rev. Nephrol.
, vol.5
, pp. 259-269
-
-
Kanjanabuch, T.1
-
11
-
-
38349142233
-
Acute postinfectious glomerulonephritis in the modern era: experience with 86 adults and review of the literature
-
Nasr S.H., et al. Acute postinfectious glomerulonephritis in the modern era: experience with 86 adults and review of the literature. Medicine (Baltimore) 2008, 87:21-32.
-
(2008)
Medicine (Baltimore)
, vol.87
, pp. 21-32
-
-
Nasr, S.H.1
-
12
-
-
77954427551
-
Membranoproliferative glomerulonephritis
-
Alchi B., Jayne D. Membranoproliferative glomerulonephritis. Pediatr. Nephrol. 2010, 25:1409-1418.
-
(2010)
Pediatr. Nephrol.
, vol.25
, pp. 1409-1418
-
-
Alchi, B.1
Jayne, D.2
-
13
-
-
20844447869
-
Pathogenic mechanisms in membranoproliferative glomerulonephritis
-
Smith K.D., Alpers C.E. Pathogenic mechanisms in membranoproliferative glomerulonephritis. Curr. Opin. Nephrol. Hypertens. 2005, 14:396-403.
-
(2005)
Curr. Opin. Nephrol. Hypertens.
, vol.14
, pp. 396-403
-
-
Smith, K.D.1
Alpers, C.E.2
-
14
-
-
34147180032
-
Primary glomerulonephritis with isolated C3 deposits: a new entity which shares common genetic risk factors with haemolytic uraemic syndrome
-
Servais A., et al. Primary glomerulonephritis with isolated C3 deposits: a new entity which shares common genetic risk factors with haemolytic uraemic syndrome. J. Med. Genet. 2007, 44:193-199.
-
(2007)
J. Med. Genet.
, vol.44
, pp. 193-199
-
-
Servais, A.1
-
15
-
-
34548491156
-
New approaches to the treatment of dense deposit disease
-
Smith R.J., et al. New approaches to the treatment of dense deposit disease. J. Am. Soc. Nephrol. 2007, 18:2447-2456.
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
, pp. 2447-2456
-
-
Smith, R.J.1
-
16
-
-
64949093413
-
Glomeruli of Dense Deposit Disease contain components of the alternative and terminal complement pathway
-
Sethi S., et al. Glomeruli of Dense Deposit Disease contain components of the alternative and terminal complement pathway. Kidney Int. 2009, 75:952-960.
-
(2009)
Kidney Int.
, vol.75
, pp. 952-960
-
-
Sethi, S.1
-
17
-
-
33644659729
-
Anti-glomerular basement membrane glomerulonephritis: a morphologic study of 80 cases
-
Fischer E.G., Lager D.J. Anti-glomerular basement membrane glomerulonephritis: a morphologic study of 80 cases. Am. J. Clin. Pathol. 2006, 125:445-450.
-
(2006)
Am. J. Clin. Pathol.
, vol.125
, pp. 445-450
-
-
Fischer, E.G.1
Lager, D.J.2
-
18
-
-
21244503148
-
The role of neutrophils in the induction of glomerulonephritis by anti-myeloperoxidase antibodies
-
Xiao H., et al. The role of neutrophils in the induction of glomerulonephritis by anti-myeloperoxidase antibodies. Am. J. Pathol. 2005, 167:39-45.
-
(2005)
Am. J. Pathol.
, vol.167
, pp. 39-45
-
-
Xiao, H.1
-
19
-
-
0031985125
-
Pathogenesis of the vascular and glomerular damage in ANCA-positive vasculitis
-
Jennette J.C., Falk R.J. Pathogenesis of the vascular and glomerular damage in ANCA-positive vasculitis. Nephrol. Dial. Transplant. 1998, 13(Suppl. 1):16-20.
-
(1998)
Nephrol. Dial. Transplant.
, vol.13
, Issue.SUPPL. 1
, pp. 16-20
-
-
Jennette, J.C.1
Falk, R.J.2
-
20
-
-
73649084824
-
Pathogenesis of small vessel vasculitis associated with autoantibodies to neutrophil cytoplasmic antigens: new insights from animal models
-
Kain R., et al. Pathogenesis of small vessel vasculitis associated with autoantibodies to neutrophil cytoplasmic antigens: new insights from animal models. Curr. Opin. Rheumatol. 2010, 22:15-20.
-
(2010)
Curr. Opin. Rheumatol.
, vol.22
, pp. 15-20
-
-
Kain, R.1
-
21
-
-
75749119257
-
Banff '09 meeting report: antibody mediated graft deterioration and implementation of Banff working groups
-
Sis B., et al. Banff '09 meeting report: antibody mediated graft deterioration and implementation of Banff working groups. Am. J. Transplant. 2010, 10:464-471.
-
(2010)
Am. J. Transplant.
, vol.10
, pp. 464-471
-
-
Sis, B.1
-
22
-
-
0034050692
-
Pathogenesis of ANCA-associated systemic vasculitis
-
Harper L., Savage C.O. Pathogenesis of ANCA-associated systemic vasculitis. J. Pathol. 2000, 190:349-359.
-
(2000)
J. Pathol.
, vol.190
, pp. 349-359
-
-
Harper, L.1
Savage, C.O.2
-
23
-
-
40349088701
-
New insight into the pathogenesis of vasculitis associated with antineutrophil cytoplasmic autoantibodies
-
Jennette J.C., Falk R.J. New insight into the pathogenesis of vasculitis associated with antineutrophil cytoplasmic autoantibodies. Curr. Opin. Rheumatol. 2008, 20:55-60.
-
(2008)
Curr. Opin. Rheumatol.
, vol.20
, pp. 55-60
-
-
Jennette, J.C.1
Falk, R.J.2
-
24
-
-
0027932468
-
Neutrophil activation in vitro and in vivo in Wegener's granulomatosis
-
Brouwer E., et al. Neutrophil activation in vitro and in vivo in Wegener's granulomatosis. Kidney Int. 1994, 45:1120-1131.
-
(1994)
Kidney Int.
, vol.45
, pp. 1120-1131
-
-
Brouwer, E.1
-
25
-
-
0036707876
-
Neutrophil membrane expression of proteinase 3 (PR3) is related to relapse in PR3-ANCA-associated vasculitis
-
Rarok A.A., et al. Neutrophil membrane expression of proteinase 3 (PR3) is related to relapse in PR3-ANCA-associated vasculitis. J. Am. Soc. Nephrol. 2002, 13:2232-2238.
-
(2002)
J. Am. Soc. Nephrol.
, vol.13
, pp. 2232-2238
-
-
Rarok, A.A.1
-
26
-
-
54049148978
-
Homeostatic regulation of blood neutrophil counts
-
von Vietinghoff S., Ley K. Homeostatic regulation of blood neutrophil counts. J. Immunol. 2008, 181:5183-5188.
-
(2008)
J. Immunol.
, vol.181
, pp. 5183-5188
-
-
von Vietinghoff, S.1
Ley, K.2
-
27
-
-
0032796115
-
Glomerular inflammation: use of genetically deficient mice to elucidate the roles of leukocyte adhesion molecules and Fc-gamma receptors in vivo
-
Mayadas T.N., et al. Glomerular inflammation: use of genetically deficient mice to elucidate the roles of leukocyte adhesion molecules and Fc-gamma receptors in vivo. Curr. Opin. Nephrol. Hypertens. 1999, 8:293-298.
-
(1999)
Curr. Opin. Nephrol. Hypertens.
, vol.8
, pp. 293-298
-
-
Mayadas, T.N.1
-
28
-
-
84883832799
-
A role of polymorphonuclear leukocytes and complement in nephrotoxic nephritis
-
Cochrane C.G., et al. A role of polymorphonuclear leukocytes and complement in nephrotoxic nephritis. J. Exp. Med. 1965, 122:99-116.
-
(1965)
J. Exp. Med.
, vol.122
, pp. 99-116
-
-
Cochrane, C.G.1
-
29
-
-
33748499609
-
Thrombotic microangiopathies: an update
-
Franchini M. Thrombotic microangiopathies: an update. Hematology 2006, 11:139-146.
-
(2006)
Hematology
, vol.11
, pp. 139-146
-
-
Franchini, M.1
-
30
-
-
70349694116
-
Mac-1 (CD11b/CD18) links inflammation and thrombosis after glomerular injury
-
Hirahashi J., et al. Mac-1 (CD11b/CD18) links inflammation and thrombosis after glomerular injury. Circulation 2009, 120:1255-1265.
-
(2009)
Circulation
, vol.120
, pp. 1255-1265
-
-
Hirahashi, J.1
-
31
-
-
33646381359
-
Pathogenesis of vascular inflammation by anti-neutrophil cytoplasmic antibodies
-
Jennette J.C., et al. Pathogenesis of vascular inflammation by anti-neutrophil cytoplasmic antibodies. J. Am. Soc. Nephrol. 2006, 17:1235-1242.
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 1235-1242
-
-
Jennette, J.C.1
-
32
-
-
77952990847
-
Th17 cells promote autoimmune anti-myeloperoxidase glomerulonephritis
-
Gan P.Y., et al. Th17 cells promote autoimmune anti-myeloperoxidase glomerulonephritis. J. Am. Soc. Nephrol. 2010, 21:925-931.
-
(2010)
J. Am. Soc. Nephrol.
, vol.21
, pp. 925-931
-
-
Gan, P.Y.1
-
33
-
-
44649123547
-
Human neutrophil Fcgamma receptors initiate and play specialized nonredundant roles in antibody-mediated inflammatory diseases
-
Tsuboi N., et al. Human neutrophil Fcgamma receptors initiate and play specialized nonredundant roles in antibody-mediated inflammatory diseases. Immunity 2008, 28:833-846.
-
(2008)
Immunity
, vol.28
, pp. 833-846
-
-
Tsuboi, N.1
-
34
-
-
27544471786
-
Conditional ablation of macrophages halts progression of crescentic glomerulonephritis
-
Duffield J.S., et al. Conditional ablation of macrophages halts progression of crescentic glomerulonephritis. Am. J. Pathol. 2005, 167:1207-1219.
-
(2005)
Am. J. Pathol.
, vol.167
, pp. 1207-1219
-
-
Duffield, J.S.1
-
35
-
-
33646879417
-
What do mouse models teach us about human SLE?
-
Liu K., Mohan C. What do mouse models teach us about human SLE?. Clin. Immunol. 2006, 119:123-130.
-
(2006)
Clin. Immunol.
, vol.119
, pp. 123-130
-
-
Liu, K.1
Mohan, C.2
-
36
-
-
38549096975
-
Microarray analysis of glomerular gene expression in murine lupus nephritis
-
Teramoto K., et al. Microarray analysis of glomerular gene expression in murine lupus nephritis. J. Pharmacol. Sci. 2008, 106:56-67.
-
(2008)
J. Pharmacol. Sci.
, vol.106
, pp. 56-67
-
-
Teramoto, K.1
-
37
-
-
23844457665
-
C5a promotes development of experimental lupus nephritis which can be blocked with a specific receptor antagonist
-
Bao L., et al. C5a promotes development of experimental lupus nephritis which can be blocked with a specific receptor antagonist. Eur. J. Immunol. 2005, 35:2496-2506.
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 2496-2506
-
-
Bao, L.1
-
38
-
-
70349238893
-
The role of IL-23/IL-17 axis in lupus nephritis
-
Zhang Z., et al. The role of IL-23/IL-17 axis in lupus nephritis. J. Immunol. 2009, 183:3160-3169.
-
(2009)
J. Immunol.
, vol.183
, pp. 3160-3169
-
-
Zhang, Z.1
-
39
-
-
0031571332
-
Intercellular adhesion molecule-1 deficiency protects MRL/MpJ-Fas(lpr) mice from early lethality
-
Bullard D.C., et al. Intercellular adhesion molecule-1 deficiency protects MRL/MpJ-Fas(lpr) mice from early lethality. J. Immunol. 1997, 159:2058-2067.
-
(1997)
J. Immunol.
, vol.159
, pp. 2058-2067
-
-
Bullard, D.C.1
-
40
-
-
3242752599
-
Loss of LFA-1, but not Mac-1, protects MRL/MpJ-Fas(lpr) mice from autoimmune disease
-
Kevil C.G., et al. Loss of LFA-1, but not Mac-1, protects MRL/MpJ-Fas(lpr) mice from autoimmune disease. Am. J. Pathol. 2004, 165:609-616.
-
(2004)
Am. J. Pathol.
, vol.165
, pp. 609-616
-
-
Kevil, C.G.1
-
41
-
-
0036699540
-
Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H
-
Pickering M.C., et al. Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H. Nat. Genet. 2002, 31:424-428.
-
(2002)
Nat. Genet.
, vol.31
, pp. 424-428
-
-
Pickering, M.C.1
-
42
-
-
33745441327
-
Prevention of C5 activation ameliorates spontaneous and experimental glomerulonephritis in factor H-deficient mice
-
Pickering M.C., et al. Prevention of C5 activation ameliorates spontaneous and experimental glomerulonephritis in factor H-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:9649-9654.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 9649-9654
-
-
Pickering, M.C.1
-
43
-
-
0029770138
-
The membrane attack complex of complement induces interleukin-8 and monocyte chemoattractant protein-1 secretion from human umbilical vein endothelial cells
-
Kilgore K.S., et al. The membrane attack complex of complement induces interleukin-8 and monocyte chemoattractant protein-1 secretion from human umbilical vein endothelial cells. Am. J. Pathol. 1996, 149:953-961.
-
(1996)
Am. J. Pathol.
, vol.149
, pp. 953-961
-
-
Kilgore, K.S.1
-
44
-
-
0029112745
-
Enhancement by the complement membrane attack complex of tumor necrosis factor-alpha-induced endothelial cell expression of E-selectin and ICAM-1
-
Kilgore K.S., et al. Enhancement by the complement membrane attack complex of tumor necrosis factor-alpha-induced endothelial cell expression of E-selectin and ICAM-1. J. Immunol. 1995, 155:1434-1441.
-
(1995)
J. Immunol.
, vol.155
, pp. 1434-1441
-
-
Kilgore, K.S.1
-
45
-
-
0034864247
-
An experimental model of cryoglobulin-associated vasculitis in mice
-
Pastore Y., et al. An experimental model of cryoglobulin-associated vasculitis in mice. Springer Semin. Immunopathol. 2001, 23:315-329.
-
(2001)
Springer Semin. Immunopathol.
, vol.23
, pp. 315-329
-
-
Pastore, Y.1
-
46
-
-
0029862692
-
Polymorphonuclear leukocytes play a key role in the generation of " wire-loop" lesions induced by a murine IgG3 rheumatoid factor
-
Fulpius T., et al. Polymorphonuclear leukocytes play a key role in the generation of " wire-loop" lesions induced by a murine IgG3 rheumatoid factor. Kidney Int. 1996, 49:647-655.
-
(1996)
Kidney Int.
, vol.49
, pp. 647-655
-
-
Fulpius, T.1
-
47
-
-
34548230927
-
Getting to the site of inflammation: the leukocyte adhesion cascade updated
-
Ley K., et al. Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat. Rev. Immunol. 2007, 7:678-689.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 678-689
-
-
Ley, K.1
-
48
-
-
41549126642
-
Targeting leukocytes in immune glomerular diseases
-
Kitching A.R., et al. Targeting leukocytes in immune glomerular diseases. Curr. Med. Chem. 2008, 15:448-458.
-
(2008)
Curr. Med. Chem.
, vol.15
, pp. 448-458
-
-
Kitching, A.R.1
-
49
-
-
0033105863
-
P-selectin deficiency exacerbates experimental glomerulonephritis: a protective role for endothelial P-selectin in inflammation
-
Rosenkranz A.R., et al. P-selectin deficiency exacerbates experimental glomerulonephritis: a protective role for endothelial P-selectin in inflammation. J. Clin. Invest. 1999, 103:649-659.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 649-659
-
-
Rosenkranz, A.R.1
-
50
-
-
53249133191
-
-
Live-animal imaging of renal function by multiphoton microscopy. Curr. Protoc. Cytom. Chapter 12, Unit 12.9
-
Dunn, K.W. et al. (2007) Live-animal imaging of renal function by multiphoton microscopy. Curr. Protoc. Cytom. Chapter 12, Unit 12.9.
-
(2007)
-
-
Dunn, K.W.1
-
51
-
-
5444276621
-
C1q governs deposition of circulating immune complexes and leukocyte Fcgamma receptors mediate subsequent neutrophil recruitment
-
Stokol T., et al. C1q governs deposition of circulating immune complexes and leukocyte Fcgamma receptors mediate subsequent neutrophil recruitment. J. Exp. Med. 2004, 200:835-846.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 835-846
-
-
Stokol, T.1
-
52
-
-
44649149030
-
Role of TNF priming and adhesion molecules in neutrophil recruitment to intravascular immune complexes
-
Lauterbach M., et al. Role of TNF priming and adhesion molecules in neutrophil recruitment to intravascular immune complexes. J. Leukoc. Biol. 2008, 83:1423-1430.
-
(2008)
J. Leukoc. Biol.
, vol.83
, pp. 1423-1430
-
-
Lauterbach, M.1
-
53
-
-
34548712331
-
Immune complexes mediate rapid alterations in microvascular permeability: roles for neutrophils, complement, and platelets
-
Lister K.J., et al. Immune complexes mediate rapid alterations in microvascular permeability: roles for neutrophils, complement, and platelets. Microcirculation 2007, 14:709-722.
-
(2007)
Microcirculation
, vol.14
, pp. 709-722
-
-
Lister, K.J.1
-
54
-
-
72449160275
-
Mechanisms of immune complex-mediated neutrophil recruitment and tissue injury
-
Mayadas T.N., et al. Mechanisms of immune complex-mediated neutrophil recruitment and tissue injury. Circulation 2009, 120:2012-2024.
-
(2009)
Circulation
, vol.120
, pp. 2012-2024
-
-
Mayadas, T.N.1
-
55
-
-
33845402233
-
Deficiency of P-selectin or P-selectin glycoprotein ligand-1 leads to accelerated development of glomerulonephritis and increased expression of CC chemokine ligand 2 in lupus-prone mice
-
He X., et al. Deficiency of P-selectin or P-selectin glycoprotein ligand-1 leads to accelerated development of glomerulonephritis and increased expression of CC chemokine ligand 2 in lupus-prone mice. J. Immunol. 2006, 177:8748-8756.
-
(2006)
J. Immunol.
, vol.177
, pp. 8748-8756
-
-
He, X.1
-
56
-
-
70350552142
-
Questions about chemokine and chemokine receptor antagonism in renal inflammation
-
Anders H.J., et al. Questions about chemokine and chemokine receptor antagonism in renal inflammation. Nephron Exp. Nephrol. 2010, 114:e33-e38.
-
(2010)
Nephron Exp. Nephrol.
, vol.114
-
-
Anders, H.J.1
-
57
-
-
0030784483
-
A role for Mac-1 (CDIIb/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcgamma receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis
-
Tang T., et al. A role for Mac-1 (CDIIb/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcgamma receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis. J. Exp. Med. 1997, 186:1853-1863.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1853-1863
-
-
Tang, T.1
-
58
-
-
67650578429
-
Antimyeloperoxidase antibodies rapidly induce alpha-4-integrin-dependent glomerular neutrophil adhesion
-
Kuligowski M.P., et al. Antimyeloperoxidase antibodies rapidly induce alpha-4-integrin-dependent glomerular neutrophil adhesion. Blood 2009, 113:6485-6494.
-
(2009)
Blood
, vol.113
, pp. 6485-6494
-
-
Kuligowski, M.P.1
-
59
-
-
44049103057
-
Mechanisms of ANCA-mediated leukocyte-endothelial cell interactions in vivo
-
Nolan S.L., et al. Mechanisms of ANCA-mediated leukocyte-endothelial cell interactions in vivo. J. Am. Soc. Nephrol. 2008, 19:973-984.
-
(2008)
J. Am. Soc. Nephrol.
, vol.19
, pp. 973-984
-
-
Nolan, S.L.1
-
60
-
-
33344468233
-
Neutrophils and immunity: challenges and opportunities
-
Nathan C. Neutrophils and immunity: challenges and opportunities. Nat. Rev. Immunol. 2006, 6:173-182.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 173-182
-
-
Nathan, C.1
-
61
-
-
20644444103
-
Neutrophil beta2 integrins: moderators of life or death decisions
-
Mayadas T.N., Cullere X. Neutrophil beta2 integrins: moderators of life or death decisions. Trends Immunol. 2005, 26:388-395.
-
(2005)
Trends Immunol.
, vol.26
, pp. 388-395
-
-
Mayadas, T.N.1
Cullere, X.2
-
62
-
-
33845724468
-
Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function
-
Fialkow L., et al. Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function. Free Radic. Biol. Med. 2007, 42:153-164.
-
(2007)
Free Radic. Biol. Med.
, vol.42
, pp. 153-164
-
-
Fialkow, L.1
-
63
-
-
0036892616
-
Glomerular oxidative and antioxidative systems in experimental mesangioproliferative glomerulonephritis
-
Gaertner S.A., et al. Glomerular oxidative and antioxidative systems in experimental mesangioproliferative glomerulonephritis. J. Am. Soc. Nephrol. 2002, 13:2930-2937.
-
(2002)
J. Am. Soc. Nephrol.
, vol.13
, pp. 2930-2937
-
-
Gaertner, S.A.1
-
64
-
-
0031951557
-
Expression of iNOS, eNOS, and peroxynitrite-modified proteins in experimental anti-myeloperoxidase associated crescentic glomerulonephritis
-
Heeringa P., et al. Expression of iNOS, eNOS, and peroxynitrite-modified proteins in experimental anti-myeloperoxidase associated crescentic glomerulonephritis. Kidney Int. 1998, 53:382-393.
-
(1998)
Kidney Int.
, vol.53
, pp. 382-393
-
-
Heeringa, P.1
-
65
-
-
0025286296
-
Intraglomerular platelet aggregation and experimental glomerulonephritis
-
Poelstra K., et al. Intraglomerular platelet aggregation and experimental glomerulonephritis. Kidney Int. 1990, 37:1500-1508.
-
(1990)
Kidney Int.
, vol.37
, pp. 1500-1508
-
-
Poelstra, K.1
-
66
-
-
0347297134
-
Pre-existing glomerular immune complexes induce polymorphonuclear cell recruitment through an Fc receptor-dependent respiratory burst: potential role in the perpetuation of immune nephritis
-
Suzuki Y., et al. Pre-existing glomerular immune complexes induce polymorphonuclear cell recruitment through an Fc receptor-dependent respiratory burst: potential role in the perpetuation of immune nephritis. J. Immunol. 2003, 170:3243-3253.
-
(2003)
J. Immunol.
, vol.170
, pp. 3243-3253
-
-
Suzuki, Y.1
-
67
-
-
0242581714
-
Oxidative stress in the pathogenesis of experimental mesangial proliferative glomerulonephritis
-
Budisavljevic M.N., et al. Oxidative stress in the pathogenesis of experimental mesangial proliferative glomerulonephritis. Am. J. Physiol. Renal Physiol. 2003, 285:F1138-1148.
-
(2003)
Am. J. Physiol. Renal Physiol.
, vol.285
-
-
Budisavljevic, M.N.1
-
68
-
-
75149174337
-
NAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblasts
-
Bondi C.D., et al. NAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblasts. J. Am. Soc. Nephrol. 2010, 21:93-102.
-
(2010)
J. Am. Soc. Nephrol.
, vol.21
, pp. 93-102
-
-
Bondi, C.D.1
-
69
-
-
0028889591
-
Expression and localization of inducible nitric oxide synthase in anti-Thy-1 glomerulonephritis
-
Goto S., et al. Expression and localization of inducible nitric oxide synthase in anti-Thy-1 glomerulonephritis. Am. J. Pathol. 1995, 147:1133-1141.
-
(1995)
Am. J. Pathol.
, vol.147
, pp. 1133-1141
-
-
Goto, S.1
-
70
-
-
36749048702
-
Elastase deposits in the kidney and urinary elastase excretion in patients with glomerulonephritis - evidence for neutrophil involvement in renal injury
-
Kuzniar J., et al. Elastase deposits in the kidney and urinary elastase excretion in patients with glomerulonephritis - evidence for neutrophil involvement in renal injury. Scand. J. Urol. Nephrol. 2007, 41:527-534.
-
(2007)
Scand. J. Urol. Nephrol.
, vol.41
, pp. 527-534
-
-
Kuzniar, J.1
-
72
-
-
43049135931
-
Neutrophil elastase cleaves laminin-332 (laminin-5) generating peptides that are chemotactic for neutrophils
-
Mydel P., et al. Neutrophil elastase cleaves laminin-332 (laminin-5) generating peptides that are chemotactic for neutrophils. J. Biol. Chem. 2008, 283:9513-9522.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 9513-9522
-
-
Mydel, P.1
-
73
-
-
0029961891
-
Human leukocyte elastase is an endogenous ligand for the integrin CR3 (CD11b/CD18, Mac-1, alpha M beta 2) and modulates polymorphonuclear leukocyte adhesion
-
Cai T.Q., Wright S.D. Human leukocyte elastase is an endogenous ligand for the integrin CR3 (CD11b/CD18, Mac-1, alpha M beta 2) and modulates polymorphonuclear leukocyte adhesion. J. Exp. Med. 1996, 184:1213-1223.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1213-1223
-
-
Cai, T.Q.1
Wright, S.D.2
-
74
-
-
0024537457
-
Antiglomerular basement membrane nephritis in beige mice. Deficiency of leukocytic neutral proteinases prevents the induction of albuminuria in the heterologous phase
-
Schrijver G., et al. Antiglomerular basement membrane nephritis in beige mice. Deficiency of leukocytic neutral proteinases prevents the induction of albuminuria in the heterologous phase. J. Exp. Med. 1989, 169:1435-1448.
-
(1989)
J. Exp. Med.
, vol.169
, pp. 1435-1448
-
-
Schrijver, G.1
-
75
-
-
70350032189
-
An elegant defense: how neutrophils shape the immune response
-
Soehnlein O. An elegant defense: how neutrophils shape the immune response. Trends Immunol. 2009, 30:511-512.
-
(2009)
Trends Immunol.
, vol.30
, pp. 511-512
-
-
Soehnlein, O.1
-
76
-
-
18244390487
-
Myeloperoxidase: friend and foe
-
Klebanoff S.J. Myeloperoxidase: friend and foe. J. Leukoc. Biol. 2005, 77:598-625.
-
(2005)
J. Leukoc. Biol.
, vol.77
, pp. 598-625
-
-
Klebanoff, S.J.1
-
77
-
-
0028151632
-
Polymorphonuclear leukocytes increase glomerular albumin permeability via hypohalous acid
-
Li J.Z., et al. Polymorphonuclear leukocytes increase glomerular albumin permeability via hypohalous acid. Kidney Int. 1994, 46:1025-1030.
-
(1994)
Kidney Int.
, vol.46
, pp. 1025-1030
-
-
Li, J.Z.1
-
78
-
-
0011489860
-
Activation of the endogenous metalloproteinase, gelatinase, by triggered human neutrophils
-
Peppin G.J., Weiss S.J. Activation of the endogenous metalloproteinase, gelatinase, by triggered human neutrophils. Proc. Natl. Acad. Sci. U.S.A. 1986, 83:4322-4326.
-
(1986)
Proc. Natl. Acad. Sci. U.S.A.
, vol.83
, pp. 4322-4326
-
-
Peppin, G.J.1
Weiss, S.J.2
-
79
-
-
33947244860
-
Endogenous myeloperoxidase promotes neutrophil-mediated renal injury, but attenuates T cell immunity inducing crescentic glomerulonephritis
-
Odobasic D., et al. Endogenous myeloperoxidase promotes neutrophil-mediated renal injury, but attenuates T cell immunity inducing crescentic glomerulonephritis. J. Am. Soc. Nephrol. 2007, 18:760-770.
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
, pp. 760-770
-
-
Odobasic, D.1
-
80
-
-
41749090254
-
Anti-inflammatory and proresolving lipid mediators
-
Serhan C.N., et al. Anti-inflammatory and proresolving lipid mediators. Annu. Rev. Pathol. 2008, 3:279-312.
-
(2008)
Annu. Rev. Pathol.
, vol.3
, pp. 279-312
-
-
Serhan, C.N.1
-
81
-
-
0030935004
-
Lipoxins, leukocyte recruitment and the resolution phase of acute glomerulonephritis
-
O'Meara Y.M., Brady H.R. Lipoxins, leukocyte recruitment and the resolution phase of acute glomerulonephritis. Kidney Int. Suppl. 1997, 58:S56-61.
-
(1997)
Kidney Int. Suppl.
, vol.58
-
-
O'Meara, Y.M.1
Brady, H.R.2
-
82
-
-
34447561633
-
Neutrophil granules: a library of innate immunity proteins
-
Borregaard N., et al. Neutrophil granules: a library of innate immunity proteins. Trends Immunol. 2007, 28:340-345.
-
(2007)
Trends Immunol.
, vol.28
, pp. 340-345
-
-
Borregaard, N.1
-
83
-
-
0033647240
-
The neutrophil as a cellular source of chemokines
-
Scapini P., et al. The neutrophil as a cellular source of chemokines. Immunol. Rev. 2000, 177:195-203.
-
(2000)
Immunol. Rev.
, vol.177
, pp. 195-203
-
-
Scapini, P.1
-
84
-
-
0033067441
-
Neutrophil-derived proteins: selling cytokines by the pound
-
Cassatella M.A. Neutrophil-derived proteins: selling cytokines by the pound. Adv. Immunol. 1999, 73:369-509.
-
(1999)
Adv. Immunol.
, vol.73
, pp. 369-509
-
-
Cassatella, M.A.1
-
85
-
-
0027301114
-
Expression and regulation of human neutrophil-derived macrophage inflammatory protein 1 alpha
-
Kasama T., et al. Expression and regulation of human neutrophil-derived macrophage inflammatory protein 1 alpha. J. Exp. Med. 1993, 178:63-72.
-
(1993)
J. Exp. Med.
, vol.178
, pp. 63-72
-
-
Kasama, T.1
-
86
-
-
0033561638
-
Gene expression and production of the monokine induced by IFN-gamma (MIG), IFN-inducible T cell alpha chemoattractant (I-TAC), and IFN-gamma-inducible protein-10 (IP-10) chemokines by human neutrophils
-
Gasperini S., et al. Gene expression and production of the monokine induced by IFN-gamma (MIG), IFN-inducible T cell alpha chemoattractant (I-TAC), and IFN-gamma-inducible protein-10 (IP-10) chemokines by human neutrophils. J. Immunol. 1999, 162:4928-4937.
-
(1999)
J. Immunol.
, vol.162
, pp. 4928-4937
-
-
Gasperini, S.1
-
87
-
-
16844373045
-
A novel role for neutrophils as a source of T cell-recruiting chemokines IP-10 and Mig during the DTH response to HSV-1 antigen
-
Molesworth-Kenyon S.J., et al. A novel role for neutrophils as a source of T cell-recruiting chemokines IP-10 and Mig during the DTH response to HSV-1 antigen. J. Leukoc. Biol. 2005, 77:552-559.
-
(2005)
J. Leukoc. Biol.
, vol.77
, pp. 552-559
-
-
Molesworth-Kenyon, S.J.1
-
88
-
-
70350012444
-
Polymorphonuclear neutrophils and T lymphocytes: strange bedfellows or brothers in arms?
-
Muller I., et al. Polymorphonuclear neutrophils and T lymphocytes: strange bedfellows or brothers in arms?. Trends Immunol. 2009, 30:522-530.
-
(2009)
Trends Immunol.
, vol.30
, pp. 522-530
-
-
Muller, I.1
-
89
-
-
63849337703
-
Activation of dendritic cells by polymorphonuclear neutrophils
-
Boudaly S. Activation of dendritic cells by polymorphonuclear neutrophils. Front. Biosci. 2009, 14:1589-1595.
-
(2009)
Front. Biosci.
, vol.14
, pp. 1589-1595
-
-
Boudaly, S.1
-
90
-
-
51049113366
-
Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation
-
Proost P., et al. Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation. J. Exp. Med. 2008, 205:2085-2097.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2085-2097
-
-
Proost, P.1
-
92
-
-
0031430418
-
A role for P-selectin in neutrophil and platelet infiltration in immune complex glomerulonephritis
-
Zachem C.R., et al. A role for P-selectin in neutrophil and platelet infiltration in immune complex glomerulonephritis. J. Am. Soc. Nephrol. 1997, 8:1838-1844.
-
(1997)
J. Am. Soc. Nephrol.
, vol.8
, pp. 1838-1844
-
-
Zachem, C.R.1
-
93
-
-
0024440596
-
Mechanisms and kinetics for platelet and neutrophil localization in immune complex nephritis
-
Johnson R.J., et al. Mechanisms and kinetics for platelet and neutrophil localization in immune complex nephritis. Kidney Int. 1989, 36:780-789.
-
(1989)
Kidney Int.
, vol.36
, pp. 780-789
-
-
Johnson, R.J.1
-
94
-
-
0034909732
-
Effects of a new synthetic selectin blocker in an acute rat thrombotic glomerulonephritis
-
Ito I., et al. Effects of a new synthetic selectin blocker in an acute rat thrombotic glomerulonephritis. Am. J. Kidney Dis. 2001, 38:265-273.
-
(2001)
Am. J. Kidney Dis.
, vol.38
, pp. 265-273
-
-
Ito, I.1
-
95
-
-
0028094759
-
Fibrinogen mediates platelet-polymorphonuclear leukocyte cooperation during immune-complex glomerulonephritis in rats
-
Wu X., et al. Fibrinogen mediates platelet-polymorphonuclear leukocyte cooperation during immune-complex glomerulonephritis in rats. J. Clin. Invest. 1994, 94:928-936.
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 928-936
-
-
Wu, X.1
-
96
-
-
73849111343
-
Dangerous connections: neutrophils and the phagocytic clearance of activated platelets
-
Manfredi A.A., et al. Dangerous connections: neutrophils and the phagocytic clearance of activated platelets. Curr. Opin. Hematol. 2010, 17:3-8.
-
(2010)
Curr. Opin. Hematol.
, vol.17
, pp. 3-8
-
-
Manfredi, A.A.1
-
97
-
-
72049127823
-
Th1 and Th17 cells induce proliferative glomerulonephritis
-
Summers S.A., et al. Th1 and Th17 cells induce proliferative glomerulonephritis. J. Am. Soc. Nephrol. 2009, 20:2518-2524.
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, pp. 2518-2524
-
-
Summers, S.A.1
-
98
-
-
61949463911
-
IL-17 and Th17 Cells
-
Korn T., et al. IL-17 and Th17 Cells. Annu. Rev. Immunol. 2009, 27:485-517.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 485-517
-
-
Korn, T.1
-
99
-
-
0031157030
-
Neutrophil production of IL-12 and IL-10 in candidiasis and efficacy of IL-12 therapy in neutropenic mice
-
Romani L., et al. Neutrophil production of IL-12 and IL-10 in candidiasis and efficacy of IL-12 therapy in neutropenic mice. J. Immunol. 1997, 158:5349-5356.
-
(1997)
J. Immunol.
, vol.158
, pp. 5349-5356
-
-
Romani, L.1
-
100
-
-
0031093565
-
An immunoregulatory role for neutrophils in CD4+ T helper subset selection in mice with candidiasis
-
Romani L., et al. An immunoregulatory role for neutrophils in CD4+ T helper subset selection in mice with candidiasis. J. Immunol. 1997, 158:2356-2362.
-
(1997)
J. Immunol.
, vol.158
, pp. 2356-2362
-
-
Romani, L.1
-
101
-
-
0344413013
-
Neutrophils sustain pathogenic CD8+ T cell responses in the heart
-
Grabie N., et al. Neutrophils sustain pathogenic CD8+ T cell responses in the heart. Am. J. Pathol. 2003, 163:2413-2420.
-
(2003)
Am. J. Pathol.
, vol.163
, pp. 2413-2420
-
-
Grabie, N.1
-
102
-
-
0035187247
-
Polymorphonuclear neutrophils in Wegener's granulomatosis acquire characteristics of antigen presenting cells
-
Iking-Konert C., et al. Polymorphonuclear neutrophils in Wegener's granulomatosis acquire characteristics of antigen presenting cells. Kidney Int. 2001, 60:2247-2262.
-
(2001)
Kidney Int.
, vol.60
, pp. 2247-2262
-
-
Iking-Konert, C.1
-
103
-
-
27744536534
-
Transdifferentiation of polymorphonuclear neutrophils to dendritic-like cells at the site of inflammation in rheumatoid arthritis: evidence for activation by T cells
-
Iking-Konert C., et al. Transdifferentiation of polymorphonuclear neutrophils to dendritic-like cells at the site of inflammation in rheumatoid arthritis: evidence for activation by T cells. Ann. Rheum. Dis. 2005, 64:1436-1442.
-
(2005)
Ann. Rheum. Dis.
, vol.64
, pp. 1436-1442
-
-
Iking-Konert, C.1
-
104
-
-
33748127113
-
Suppression of T-cell functions by human granulocyte arginase
-
Munder M., et al. Suppression of T-cell functions by human granulocyte arginase. Blood 2006, 108:1627-1634.
-
(2006)
Blood
, vol.108
, pp. 1627-1634
-
-
Munder, M.1
-
105
-
-
17044428026
-
Neutrophils that infiltrate the central nervous system regulate T cell responses
-
Zehntner S.P., et al. Neutrophils that infiltrate the central nervous system regulate T cell responses. J. Immunol. 2005, 174:5124-5131.
-
(2005)
J. Immunol.
, vol.174
, pp. 5124-5131
-
-
Zehntner, S.P.1
-
106
-
-
27744583959
-
Close encounters of neutrophils and DCs
-
van Gisbergen K.P., et al. Close encounters of neutrophils and DCs. Trends Immunol. 2005, 26:626-631.
-
(2005)
Trends Immunol.
, vol.26
, pp. 626-631
-
-
van Gisbergen, K.P.1
-
107
-
-
0037378907
-
Depletion of neutrophils in IL-10(-/-) mice delays clearance of gastric Helicobacter infection and decreases the Th1 immune response to Helicobacter
-
Ismail H.F., et al. Depletion of neutrophils in IL-10(-/-) mice delays clearance of gastric Helicobacter infection and decreases the Th1 immune response to Helicobacter. J. Immunol. 2003, 170:3782-3789.
-
(2003)
J. Immunol.
, vol.170
, pp. 3782-3789
-
-
Ismail, H.F.1
-
108
-
-
0035284832
-
Early recruitment of neutrophils determines subsequent T1/T2 host responses in a murine model of Legionella pneumophila pneumonia
-
Tateda K., et al. Early recruitment of neutrophils determines subsequent T1/T2 host responses in a murine model of Legionella pneumophila pneumonia. J. Immunol. 2001, 166:3355-3361.
-
(2001)
J. Immunol.
, vol.166
, pp. 3355-3361
-
-
Tateda, K.1
-
109
-
-
41449105534
-
Constitutive neutrophil apoptosis: mechanisms and regulation
-
Luo H.R., Loison F. Constitutive neutrophil apoptosis: mechanisms and regulation. Am. J. Hematol. 2008, 83:288-295.
-
(2008)
Am. J. Hematol.
, vol.83
, pp. 288-295
-
-
Luo, H.R.1
Loison, F.2
-
110
-
-
73849089140
-
New insights into the mechanisms controlling neutrophil survival
-
Cabrini M., et al. New insights into the mechanisms controlling neutrophil survival. Curr. Opin. Hematol. 2010, 17:31-35.
-
(2010)
Curr. Opin. Hematol.
, vol.17
, pp. 31-35
-
-
Cabrini, M.1
-
111
-
-
0037083341
-
Lipopolysaccharide induces rapid production of IL-10 by monocytes in the presence of apoptotic neutrophils
-
Byrne A., Reen D.J. Lipopolysaccharide induces rapid production of IL-10 by monocytes in the presence of apoptotic neutrophils. J. Immunol. 2002, 168:1968-1977.
-
(2002)
J. Immunol.
, vol.168
, pp. 1968-1977
-
-
Byrne, A.1
Reen, D.J.2
-
112
-
-
15244344110
-
Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17
-
Stark M.A., et al. Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity 2005, 22:285-294.
-
(2005)
Immunity
, vol.22
, pp. 285-294
-
-
Stark, M.A.1
-
113
-
-
0036143018
-
Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation
-
Huynh M.L., et al. Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation. J. Clin. Invest. 2002, 109:41-50.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 41-50
-
-
Huynh, M.L.1
-
114
-
-
0041427760
-
Apoptotic cells and innate immune stimuli combine to regulate macrophage cytokine secretion
-
Lucas M., et al. Apoptotic cells and innate immune stimuli combine to regulate macrophage cytokine secretion. J. Immunol. 2003, 171:2610-2615.
-
(2003)
J. Immunol.
, vol.171
, pp. 2610-2615
-
-
Lucas, M.1
-
115
-
-
0041571629
-
Dendritic cell uptake of human apoptotic and necrotic neutrophils inhibits CD40, CD80, and CD86 expression and reduces allogeneic T cell responses: relevance to systemic vasculitis
-
Clayton A.R., et al. Dendritic cell uptake of human apoptotic and necrotic neutrophils inhibits CD40, CD80, and CD86 expression and reduces allogeneic T cell responses: relevance to systemic vasculitis. Arthritis Rheum. 2003, 48:2362-2374.
-
(2003)
Arthritis Rheum.
, vol.48
, pp. 2362-2374
-
-
Clayton, A.R.1
-
116
-
-
34250684588
-
Spontaneous or Mycobacterium tuberculosis-induced apoptotic neutrophils exert opposite effects on the dendritic cell-mediated immune response
-
Aleman M., et al. Spontaneous or Mycobacterium tuberculosis-induced apoptotic neutrophils exert opposite effects on the dendritic cell-mediated immune response. Eur. J. Immunol. 2007, 37:1524-1537.
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 1524-1537
-
-
Aleman, M.1
-
117
-
-
70350001718
-
Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps
-
Yousefi S., et al. Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps. Cell Death Differ. 2009, 16:1438-1444.
-
(2009)
Cell Death Differ.
, vol.16
, pp. 1438-1444
-
-
Yousefi, S.1
-
118
-
-
40749128547
-
Histone deimination as a response to inflammatory stimuli in neutrophils
-
Neeli I., et al. Histone deimination as a response to inflammatory stimuli in neutrophils. J. Immunol. 2008, 180:1895-1902.
-
(2008)
J. Immunol.
, vol.180
, pp. 1895-1902
-
-
Neeli, I.1
-
119
-
-
67349279881
-
Netting neutrophils in autoimmune small-vessel vasculitis
-
Kessenbrock K., et al. Netting neutrophils in autoimmune small-vessel vasculitis. Nat. Med. 2009, 15:623-625.
-
(2009)
Nat. Med.
, vol.15
, pp. 623-625
-
-
Kessenbrock, K.1
-
120
-
-
43549114589
-
Neutrophil-selective CD18 silencing using RNA interference in vivo
-
Cullere X., et al. Neutrophil-selective CD18 silencing using RNA interference in vivo. Blood 2008, 111:3591-3598.
-
(2008)
Blood
, vol.111
, pp. 3591-3598
-
-
Cullere, X.1
-
121
-
-
33751197936
-
R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation
-
Braselmann S., et al. R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation. J. Pharmacol. Exp. Ther. 2006, 319:998-1008.
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.319
, pp. 998-1008
-
-
Braselmann, S.1
-
122
-
-
34547849752
-
Inflammation and bone erosion are suppressed in models of rheumatoid arthritis following treatment with a novel Syk inhibitor
-
Pine P.R., et al. Inflammation and bone erosion are suppressed in models of rheumatoid arthritis following treatment with a novel Syk inhibitor. Clin. Immunol. 2007, 124:244-257.
-
(2007)
Clin. Immunol.
, vol.124
, pp. 244-257
-
-
Pine, P.R.1
-
123
-
-
43949092440
-
An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupus
-
Bahjat F.R., et al. An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupus. Arthritis Rheum. 2008, 58:1433-1444.
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 1433-1444
-
-
Bahjat, F.R.1
-
124
-
-
55849114400
-
Treatment of rheumatoid arthritis with a Syk kinase inhibitor: a twelve-week, randomized, placebo-controlled trial
-
Weinblatt M.E., et al. Treatment of rheumatoid arthritis with a Syk kinase inhibitor: a twelve-week, randomized, placebo-controlled trial. Arthritis Rheum. 2008, 58:3309-3318.
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 3309-3318
-
-
Weinblatt, M.E.1
-
125
-
-
34547922794
-
Syk kinase as a treatment target for therapy in autoimmune diseases
-
Kyttaris V.C., Tsokos G.C. Syk kinase as a treatment target for therapy in autoimmune diseases. Clin. Immunol. 2007, 124:235-237.
-
(2007)
Clin. Immunol.
, vol.124
, pp. 235-237
-
-
Kyttaris, V.C.1
Tsokos, G.C.2
-
126
-
-
58149392986
-
Inhibition of destructive autoimmune arthritis in FcgammaRIIa transgenic mice by small chemical entities
-
Pietersz G.A., et al. Inhibition of destructive autoimmune arthritis in FcgammaRIIa transgenic mice by small chemical entities. Immunol. Cell Biol. 2009, 87:3-12.
-
(2009)
Immunol. Cell Biol.
, vol.87
, pp. 3-12
-
-
Pietersz, G.A.1
|