Expression of iNOS, eNOS, and peroxynitrite-modified proteins in experimental anti-myeloperoxidase associated crescentic glomerulonephritis

Kidney International

Volumn 53, Issue 2, 1998, Pages 382-393

  Heeringa, Peter ^a   Van Goor, Harry ^a   Moshage, Han ^a   Klok, Pieter A ^a   Huitema, Minke G ^a   De Jager, Alie ^a   Schep, Anja J ^a   Kallenberg, Cees G M ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Anti myeloperoxidase and crescentic GN; Glomerulonephritis; Nitric oxide radicals; Peroxynitrite modified proteins

Indexed keywords

NITRIC OXIDE SYNTHASE; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; EXPERIMENTAL MODEL; GLOMERULONEPHRITIS; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATORY INFILTRATE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; THROMBOCYTE AGGREGATION;

EID: 0031951557     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1998.00780.x     Document Type: Article

References (52)

1. COUSER WG: Rapidly progressive glomerulonephritis: Classification, pathogenetic mechanisms, and therapy. Am J Kidney Dis 11:449-164, 1988
2. FALK RJ, HOGAN S, CAREY TS, JENNETTE JC: Clinical course of antineutrophil cytoplasmic autoantbodies-associated glomerulonephritis and systemic vasculitis. Ann Intern Med 113:656-663, 1990
3. GERMUTH FG, VALDES AJ, TAYLOR JJ, WISE OL, RODRIGUEZ E: Fatal immune complex glomerulonephritis without immune deposits. John Hopkins Med J 136:189-192, 1975
4. STILMANT MM, BOLTON WK, STURGILL BG, SCHMITT GW, COUSER WG: Crescentic glomerulonephritis without immune deposits: Clinicopathologic features. Kidney Int 15:184-195, 1979
5. RONCO P, VERROUSI P, MIGNON F, KOURILSKY O, VANHILLE P, MEYRIER A, MERY JP, MOREL-MAROGER L: Immunopathological studies of polyarteritis nodosa and Wegener's granulomatosis: A report of 43 patients with 51 biopsies. Quart J Med 10:141-148, 1983
6. GOLDSCHMEDING R, VAN DER SCHOOT CE, TEN BOKKEL-HUININK D, HACK CE, VAN DEN ENDE CE, KALLENBERG CGM, VON DEM BORNE AEGK: Wegener's granulomatosis autoantibodies identify a novel diisopropylfluorophosphate-binding protein in the lysosomes of normal human neutrophils. J Clin Invest 84:1577-1587, 1989
7. LÜDEMANN J, UTECHT B, GROSS WL: Anti-neutrophil cytoplasmic antibodies in Wegener's granulomatosis recognize an elastinolytic enzyme. J Exp Med 171:357-362, 1990
8. FALK RJ, JENNETTE JC: Anti-neutrophil cytoplasmic autoantibodies with specificty for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N Engl J Med 318:1651-1657, 1988
9. KALLENBERG CGM, BROUWER H, WEENING JJ, COHEN TERVAERT JW: Anti-neutrophil cytoplasmic antibodies: Current diagnostic and pathophysiological potential. Kidney Int 46:1-15, 1994
10. MULDER AHL, HEERINGA P, BROUWER E, LIMBURG PC, KALLENBERG CGM: Activation of granulocytes by anti-neutrophil cytoplasmic antibodies (ANCA): a FcgammaRII-depcndent process. Clin Exp Immunol 78:270-278, 1994
11. FALK RJ, TERRELL RS, CHARLES LA, JENNETTE JC: Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro. Proc Natl Acad Sci USA 87:4115-4119, 1990
12. BROUWER E, HUITEMA MG, KLOK PA, DE WEERD H, COHEN TERVAERT JW, WEENING JJ, KALLENBERG CGM: Anti-myeloperoxidase associated proliferative glomerulonephritis; an animal model. J Exp Med 177:905-914, 1993
13. BARICOS WH, SHAH SV: Proteolytic enzymes as mediators of glomerular injury. Kidney Int 40:161-173, 1991
14. WEISS SJ: Tissue destruction by neutrophils. N Engl J Med 320:365-376, 1989
15. WRIGHT CD, MULSCH A, BUSSE R, OSSWALD H: Generation of nitric oxide by human neutrophils. Biochem Biophysc Res Commun 170: 1769-1774, 1988
16. HIBBS JB JR, TAINTOR RR, VAVRIN Z, RACHLIN EM: Nitric oxide: A cytotoxic activated macrophage effector molecule. Biochem Biophys Res Commun 157:87-94, 1988
17. FURCHGOTT RF, ZAWADZKI JV: The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288:373-376, 1980
18. LYONS CR: The role of nitric oxide in inflammation. Adv Immunol 60:323-371, 1995
19. MONCADA S, HIGGS A: The L-arginine-nitric oxide pathway. N Engl J Med 329:2002-2013, 1993
20. BACHMANN S, BOSSE HM, MUNDEL P: Topography of nitric oxide synthesis by localizing constitutive NO synthases in mammalian kidney. Am J Physiol 268:F885-F898, 1995
21. UJHE K, YUEN J, HOGARTH L, DANZIGER R, STAR RA: Localization and regulation of endothelial synthase mRNA expression in rat kidney. Am J Physiol 267:F296-F302, 1994
22. HARRISON DG, SAYEGH H, OHARA Y, INOUE N, VENEMA RC: Regulation of expression of the endothelial nitric oxide synthase. Clin Exp Pharm Phys 23:251-255, 1996
23. AHN KY, MOHAUPT MG, MADSEN KM, KONE BC: In situ hybridization localization of mRNA encoding inducible nitric oxide synthase in rat kidney. Am J Physiol 267:F748-F757, 1994
24. PFEILSCHIFTER J, SCHWARZENBACH H: Interleukin 1 and tumor necrosis factor stimulate cGMP formation in rat renal mesangial cells. FEBS Lett 273:185-187, 1990
25. CATTELL V, JANSEN A: Inducible nitric oxide synthase in inflammation. Histochem J 27:777-784, 1995
26. COOK TC, SULLIVAN R: Glomerular nitrite synthesis in in situ immune complex glomerulonephritis in the rat. Am J Pathol 139:1047-1052, 1991
27. CATTELL V, COOK T, MONCADA S: Glomeruli synthesize nitrite in experimental nephrotic nephritis. Kidney Int 38:1056-1060, 1990
28. CATTELL V, LARGEN P, HEER DE E, COOK T: Glomeruli synthesize nitrite in active Heymann nephritis: The source is infiltrating macrophages. Kidney Int 40:847-851, 1991
29. KLAHR S, MORRISEY J: Renal disease: The two faces of nitric oxide. Lab Invest 72:1-3, 1995
30. LEFER AM: Nitric oxide: Nature's naturally occurring leukocyte inhibitor. Circulation 95:253-254, 1997
31. RADI R, RODRIGUEZ M, CASTRO L, TELLERI R: Inhibition of mitochondrial electron transport by peroxynitrite. Arch Biochem Biophys 308:89-94, 1994
32. PRYOR WA, SQUADRITO GL: The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide. Am J Physiol 268:L699-L722, 1995
33. RADI R, BECKMAN JS, BUSH KM, FREEMAN BA: Peroxynitrite induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide. Arch Biochem Biophys 288:481-487, 1991
34. ISCHIROPOULOS H, ZHU L, CHEN J, TSAI, MARTIN J, SMITH C, BECKMAN JS: Peroxynitrite mediated tyrosine nitration catalyzed by superoxide dismutase. Arch Biochem Biophys 298:431-437, 1992
35. MOSHAGE H, KOK B, HUIZENGA JR, JANSEN PLM: Nitrite and nitrate determination in plasma: A critical evaluation. Clin Chem 41:892-896, 1995
36. KAMPINGA J, ASPINOLL R: Thymocyte differentiation and thymic microenvironment development in the fetal rat thymus: An immunological approach, in Thymus Update (vol 3), London, Harwood Academic Publishers, 1990, p 149
37. HUNIG T, WALLNY HJ, HARTLEY JK, LAWETZKY A, TIEFENTHALER G: A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. J Exp Med 169:73-86, 1989
38. BAGCHUS WM, JEUNINK MF, ROZING J, ELEMA JD: A monoclonal antibody against rat platelets. 1. Tissue distribution in vitro and in vivo. Clin Exp Immunol 75:317-323, 1989
39. VOS TA, GOUW ASH, KLOK PA, HAVINGA R, VAN GOOR H, HUJTEMA S, ROELOFSEN H, KUIPERS F, JANSEN PLM, MOSHAGE H: Differential effects of nitric oxide synthase inhibitors on endotoxin-induced liver damage in rats. Gastroenterology (in press)
40. HELMKE RJ, BOYD RL, GERMAN VF, MANGOS JA: From growth factor dependence to growth factor responsiveness: The genesis of an alveolar macrophage cell line. In vitro Cell Dev Biol 23:567-574, 1987
41. BRIGGS RT, ROBINSON JM, KARNOVSKY ML, KARNOVSKY MJ: Superoxide production by polymorphonuclear leukocytes: A cytochemical approach. Histochemistry 84:371-378, 1986
42. POELSTRA K, BROUWER E, BALLER JFW, HARDONK MJ, BAKKER WW: Attenuation of anti-Thy1 glomerulonephritis in the rat: Anti-inflammatory activity of platelet inhibiting pharmaca. Am J Pathol 142:441-450, 1992
43. COOK T, WADDINGTON S, JANSEN A, CATTEL V: Arginase reduces nitric oxide (NO) synthesis by glomeruli in nephrotoxic nephritis and exacerbates proteinuria and glomerular thrombosis. (abstract) J Am Soc Nephrol 5:743, 1994
44. WESTBERG G, SCHULTZ PJ, RAIJ L: Exogenous nitric oxide prevents endotoxin-induced thrombosis in rats. Kidney Int 46:711-716, 1994
45. SCHULTZ PJ, RAIJ L: Endogenously synthesized nitric oxide prevents endotoxin-induced glomerular thrombosis. J Clin Invest 90:1718-1725, 1992
46. AJI W, RAVALLI S, SZABOLCS M, JIANG X, SCIACCA RR, MICHLER RE, CANNON PJ: L-Arginine prevents xanthoma development and inhibits atherosclerosis in LDL receptor knockout mice. Circulation 95:430-437, 1997
47. DUIJVESTIJN AM, VAN GOOR H, KLATTER F, MAJOOR GD, VAN BUSSEL E, VAN BREDA-VRIESMAN PJC: Antibodies defining rat endothelial cells: RECA-1, a pan-endothelial cell-specific monoclonal antibody. Lab Invest 66:459-466, 1992
48. JANSEN A, COOK T, TAYLOR M, LARGEN P, RIVEROS-MORENO V, MONCADA S, CATTEL V: Induction of nitric oxide synthase in rat immune complex glomerulonephritis. Kidney Int 45:1215-1219, 1994
49. SETOGUCHI K, TAKEYA M, AKAIKE T, SUGA M, HATTORI R, MAEDA H, ANDO M, TAKAHASHI K: Expression of inducible nitric oxide synthase and its involvement in pulmonary granulomatous inflammation in rats. Am J Pathol 149:2005-2022, 1996
50. COERS E, BROUWER E, VOS JTWM, CHAND A, HUITEMA S, HEERINGA P, KALLENBERG CGM, WEENING JJ: Podocyte expression of MHC class I and II and intercellular adhesion moldecule-1 (ICAM-1) in experimental pauci-immune crescentic glomerulonephritis. Clin Exp Immunol 98:279-286, 1994
51. NARITA I, BORDER WA, KETTELER M, NOBLE NA: Nitric oxide mediates immunologic injury to kidney mesangium in experimental glomerulonephritis. Lab Invest 72:17-24, 1995
52. NOIRI E, PERESIENI T, MILLER F, GOLIGORSKY MS: In vivo targeting of inducible No synthase with oligodeoxynucleotides protects rat kidney against ischemia. J Clin Invest 97:2377-2383, 1996