메뉴 건너뛰기




Volumn 2010, Issue , 2010, Pages

A Comprehensive in silico analysis of the functional and structural impact of SNPs in the IGF1R gene

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CYSTEINE; MESSENGER RNA; SOMATOMEDIN C RECEPTOR; MUTANT PROTEIN;

EID: 77955376154     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2010/715139     Document Type: Article
Times cited : (48)

References (41)
  • 1
    • 17044437374 scopus 로고    scopus 로고
    • Gene SNPs and mutations in clinical genetic testing: Haplotype-based testing and analysis
    • Lee J.-E., Choi J. H., Lee J. H., Lee M. G., Gene SNPs and mutations in clinical genetic testing: haplotype-based testing and analysis Mutation Research 2005 573 1-2 195 204
    • (2005) Mutation Research , vol.573 , Issue.12 , pp. 195-204
    • Lee, J.-E.1    Choi, J.H.2    Lee, J.H.3    Lee, M.G.4
  • 3
    • 18844366475 scopus 로고    scopus 로고
    • Regulatory SNPs in complex diseases: Their identification and functional validation
    • Prokunina L., Alarcn-Riquelme M. E., Regulatory SNPs in complex diseases: their identification and functional validation Expert Reviews in Molecular Medicine 2004 6 10
    • (2004) Expert Reviews in Molecular Medicine , vol.6 , Issue.10
    • Prokunina, L.1    Alarcn-Riquelme, M.E.2
  • 4
    • 77953446523 scopus 로고    scopus 로고
    • The human gene mutation database: 2008 update
    • Stenson P. D., Mort M., Ball E. V., The human gene mutation database: 2008 update Genome Medicine 2009 1 1 13
    • (2009) Genome Medicine , vol.1 , Issue.1 , pp. 13
    • Stenson, P.D.1    Mort, M.2    Ball, E.V.3
  • 5
    • 0036713510 scopus 로고    scopus 로고
    • Human non-synonymous SNPs: Server and survey
    • Ramensky V., Bork P., Sunyaev S., Human non-synonymous SNPs: server and survey Nucleic Acids Research 2002 30 17 3894 3900
    • (2002) Nucleic Acids Research , vol.30 , Issue.17 , pp. 3894-3900
    • Ramensky, V.1    Bork, P.2    Sunyaev, S.3
  • 7
    • 0033810469 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms and the future of genetic epidemiology
    • Schork N. J., Fallin D., Lanchbury J. S., Single nucleotide polymorphisms and the future of genetic epidemiology Clinical Genetics 2000 58 4 250 264
    • (2000) Clinical Genetics , vol.58 , Issue.4 , pp. 250-264
    • Schork, N.J.1    Fallin, D.2    Lanchbury, J.S.3
  • 9
    • 0034660559 scopus 로고    scopus 로고
    • Searching for genetic determinants in the new millennium
    • Risch N. J., Searching for genetic determinants in the new millennium Nature 2000 405 6788 847 856
    • (2000) Nature , vol.405 , Issue.6788 , pp. 847-856
    • Risch, N.J.1
  • 10
    • 34548614932 scopus 로고    scopus 로고
    • Identification and in silico analysis of functional SNPs of the BRCA1 gene
    • Rajasekaran R., Sudandiradoss C., Doss C. G. P., Sethumadhavan R., Identification and in silico analysis of functional SNPs of the BRCA1 gene Genomics 2007 90 4 447 452
    • (2007) Genomics , vol.90 , Issue.4 , pp. 447-452
    • Rajasekaran, R.1    Sudandiradoss, C.2    Doss, C.G.P.3    Sethumadhavan, R.4
  • 11
    • 46649114390 scopus 로고    scopus 로고
    • Identification and structural comparison of deleterious mutations in nsSNPs of ABL1 gene in chronic myeloid leukemia: A bio-informatics study
    • Doss C. G. P., Sudandiradoss C., Rajasekaran R., Purohit R., Ramanathan K., Sethumadhavan R., Identification and structural comparison of deleterious mutations in nsSNPs of ABL1 gene in chronic myeloid leukemia: a bio-informatics study Journal of Biomedical Informatics 2008 41 4 607 612
    • (2008) Journal of Biomedical Informatics , vol.41 , Issue.4 , pp. 607-612
    • Doss, C.G.P.1    Sudandiradoss, C.2    Rajasekaran, R.3    Purohit, R.4    Ramanathan, K.5    Sethumadhavan, R.6
  • 12
    • 44149083268 scopus 로고    scopus 로고
    • Effect of deleterious nsSNP on the HER2 receptor based on stability and binding affinity with herceptin: A computational approach
    • Rajasekaran R., Doss C. G. P., Sudandiradoss C., Ramanathan K., Purohit R., Sethumadhavan R., Effect of deleterious nsSNP on the HER2 receptor based on stability and binding affinity with herceptin: a computational approach Comptes Rendus Biologies 2008 331 6 409 417
    • (2008) Comptes Rendus Biologies , vol.331 , Issue.6 , pp. 409-417
    • Rajasekaran, R.1    Doss, C.G.P.2    Sudandiradoss, C.3    Ramanathan, K.4    Purohit, R.5    Sethumadhavan, R.6
  • 14
    • 77949278284 scopus 로고    scopus 로고
    • In Silico identification of significant detrimental missense mutations of EGFR and their effect with 4-anilinoquinazoline-based drugs
    • Rajasekaran R., Sethumadhavan R., In Silico identification of significant detrimental missense mutations of EGFR and their effect with 4-anilinoquinazoline-based drugs Applied Biochemistry and Biotechnology 2010 160 6 1723 1733
    • (2010) Applied Biochemistry and Biotechnology , vol.160 , Issue.6 , pp. 1723-1733
    • Rajasekaran, R.1    Sethumadhavan, R.2
  • 15
    • 14644433735 scopus 로고    scopus 로고
    • The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy
    • Warshamana-Greene G. S., Litz J., Buchdunger E., García- Echeverría C., Hofmann F., Krystal G. W., The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy Clinical Cancer Research 2005 11 4 1563 1571
    • (2005) Clinical Cancer Research , vol.11 , Issue.4 , pp. 1563-1571
    • Warshamana-Greene, G.S.1    Litz, J.2    Buchdunger, E.3    García- Echeverría, C.4    Hofmann, F.5    Krystal, G.W.6
  • 17
    • 9244242088 scopus 로고    scopus 로고
    • Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model
    • Krueckl S. L., Sikes R. A., Edlund N. M., Bell R. H., Hurtado-Coll A., Fazli L., Gleave M. E., Cox M. E., Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model Cancer Research 2004 64 23 8620 8629
    • (2004) Cancer Research , vol.64 , Issue.23 , pp. 8620-8629
    • Krueckl, S.L.1    Sikes, R.A.2    Edlund, N.M.3    Bell, R.H.4    Hurtado-Coll, A.5    Fazli, L.6    Gleave, M.E.7    Cox, M.E.8
  • 18
    • 0037092971 scopus 로고    scopus 로고
    • Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease
    • Hellawell G. O., Turner G. D. H., Davies D. R., Poulsom R., Brewster S. F., Macaulay V. M., Expression of the type 1 insulin-like growth factor receptor is up-regulated in primary prostate cancer and commonly persists in metastatic disease Cancer Research 2002 62 10 2942 2950
    • (2002) Cancer Research , vol.62 , Issue.10 , pp. 2942-2950
    • Hellawell, G.O.1    Turner, G.D.H.2    Davies, D.R.3    Poulsom, R.4    Brewster, S.F.5    Macaulay, V.M.6
  • 19
    • 53549089601 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 receptor polymorphism and ischemic stroke: A case-control study in Chinese population
    • Cheng J., Liu J., Li X., Insulin-like growth factor-1 receptor polymorphism and ischemic stroke: a case-control study in Chinese population Acta Neurologica Scandinavica 2008 118 5 333 338
    • (2008) Acta Neurologica Scandinavica , vol.118 , Issue.5 , pp. 333-338
    • Cheng, J.1    Liu, J.2    Li, X.3
  • 20
    • 33750904766 scopus 로고    scopus 로고
    • Association of insulin-like growth factor-1 receptor polymorphism in dementia
    • Garcia J., Ahmadi A., Wonnacott A., Association of insulin-like growth factor-1 receptor polymorphism in dementia Dementia and Geriatric Cognitive Disorders 2006 22 5-6 439 444
    • (2006) Dementia and Geriatric Cognitive Disorders , vol.22 , Issue.56 , pp. 439-444
    • Garcia, J.1    Ahmadi, A.2    Wonnacott, A.3
  • 21
    • 0043122919 scopus 로고    scopus 로고
    • SIFT: Predicting amino acid changes that affect protein function
    • Ng P. C., Henikoff S., SIFT: predicting amino acid changes that affect protein function Nucleic Acids Research 2003 31 13 3812 3814
    • (2003) Nucleic Acids Research , vol.31 , Issue.13 , pp. 3812-3814
    • Ng, P.C.1    Henikoff, S.2
  • 22
    • 0034191958 scopus 로고    scopus 로고
    • Towards a structural basis of human non-synonymous single nucleotide polymorphisms
    • Sunyaev S., Ramensky V., Bork P., Towards a structural basis of human non-synonymous single nucleotide polymorphisms Trends in Genetics 2000 16 5 198 200
    • (2000) Trends in Genetics , vol.16 , Issue.5 , pp. 198-200
    • Sunyaev, S.1    Ramensky, V.2    Bork, P.3
  • 24
    • 0035026704 scopus 로고    scopus 로고
    • Predicting deleterious amino acid substitutions
    • Ng P. C., Henikoff S., Predicting deleterious amino acid substitutions Genome Research 2001 11 5 863 874
    • (2001) Genome Research , vol.11 , Issue.5 , pp. 863-874
    • Ng, P.C.1    Henikoff, S.2
  • 25
    • 0036119504 scopus 로고    scopus 로고
    • Accounting for human polymorphisms predicted to affect protein function
    • Ng P. C., Henikoff S., Accounting for human polymorphisms predicted to affect protein function Genome Research 2002 12 3 436 446
    • (2002) Genome Research , vol.12 , Issue.3 , pp. 436-446
    • Ng, P.C.1    Henikoff, S.2
  • 26
    • 33750353461 scopus 로고    scopus 로고
    • Predicting the effects of amino acid substitutions on protein function
    • Ng P. C., Henikoff S., Predicting the effects of amino acid substitutions on protein function Annual Review of Genomics and Human Genetics 2006 7 61 80
    • (2006) Annual Review of Genomics and Human Genetics , vol.7 , pp. 61-80
    • Ng, P.C.1    Henikoff, S.2
  • 27
    • 0035253005 scopus 로고    scopus 로고
    • Integration of genome data and protein structures: Prediction of protein folds, protein interactions and molecular phenotypes of single nucleotide polymorphisms
    • Sunyaev S., Lathe W. III, Bork P., Integration of genome data and protein structures: prediction of protein folds, protein interactions and molecular phenotypes of single nucleotide polymorphisms Current Opinion in Structural Biology 2001 11 1 125 130
    • (2001) Current Opinion in Structural Biology , vol.11 , Issue.1 , pp. 125-130
    • Sunyaev, S.1    Lathe III, W.2    Bork, P.3
  • 28
    • 2642527702 scopus 로고    scopus 로고
    • Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function
    • Xi T., Jones I. M., Mohrenweiser H. W., Many amino acid substitution variants identified in DNA repair genes during human population screenings are predicted to impact protein function Genomics 2004 83 6 970 979
    • (2004) Genomics , vol.83 , Issue.6 , pp. 970-979
    • Xi, T.1    Jones, I.M.2    Mohrenweiser, H.W.3
  • 29
    • 0035937259 scopus 로고    scopus 로고
    • Predicting the functional consequences of non-synonymous single nucleotide polymorphisms: Structure-based assessment of amino acid variation
    • Chasman D., Adams R. M., Predicting the functional consequences of non-synonymous single nucleotide polymorphisms: structure-based assessment of amino acid variation Journal of Molecular Biology 2001 307 2 683 706
    • (2001) Journal of Molecular Biology , vol.307 , Issue.2 , pp. 683-706
    • Chasman, D.1    Adams, R.M.2
  • 31
    • 0035065485 scopus 로고    scopus 로고
    • SNPs, protein structure, and disease
    • Wang Z., Moult J., SNPs, protein structure, and disease Human Mutation 2001 17 4 263 270
    • (2001) Human Mutation , vol.17 , Issue.4 , pp. 263-270
    • Wang, Z.1    Moult, J.2
  • 36
    • 0034199476 scopus 로고    scopus 로고
    • The sequence manipulation suite: JavaScript programs for analyzing and formatting protein and DNA sequences
    • Stothard P., The sequence manipulation suite: JavaScript programs for analyzing and formatting protein and DNA sequences BioTechniques 2000 28 6 1102 1104
    • (2000) BioTechniques , vol.28 , Issue.6 , pp. 1102-1104
    • Stothard, P.1
  • 39
    • 0038637217 scopus 로고    scopus 로고
    • Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: Cues for an evolutionarily conserved mechanism of life span control
    • Bonafè M., Barbieri M., Marchegiani F., Olivieri F., Ragno E., Giampieri C., Mugianesi E., Centurelli M., Franceschi C., Paolisso G., Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control Journal of Clinical Endocrinology and Metabolism 2003 88 7 3299 3304
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , Issue.7 , pp. 3299-3304
    • Bonafè, M.1    Barbieri, M.2    Marchegiani, F.3    Olivieri, F.4    Ragno, E.5    Giampieri, C.6    Mugianesi, E.7    Centurelli, M.8    Franceschi, C.9    Paolisso, G.10
  • 40
    • 34547655600 scopus 로고    scopus 로고
    • Association of the GAA1013→GAG polymorphism of the insulin-like growth factor-1 receptor (IGF1R) gene with premature pubarche
    • Roldan M. B., White C., Witchel S. F., Association of the GAA1013→GAG polymorphism of the insulin-like growth factor-1 receptor (IGF1R) gene with premature pubarche Fertility and Sterility 2007 88 2 410 417
    • (2007) Fertility and Sterility , vol.88 , Issue.2 , pp. 410-417
    • Roldan, M.B.1    White, C.2    Witchel, S.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.