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Volumn 160, Issue 6, 2010, Pages 1723-1733

In silico identification of significant detrimental missense mutations of EGFR and their effect with 4-anilinoquinazoline-based drugs

(2) Rajasekaran, R a Sethumadhavan, Rao a

a VIT UNIVERSITY (India)

Author keywords

EGFR; Erlotinib; Gefitinib; Lapatinib; Point mutation

Indexed keywords

BINDING AFFINITIES; BINDING EFFICIENCY; COMPUTATIONAL ANALYSIS; EPIDERMAL GROWTH FACTOR RECEPTORS; ERLOTINIB; GEFITINIB; IN-SILICO; LAPATINIB; POINT MUTATIONS;

BINDING ENERGY;

EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GEFITINIB; LAPATINIB; QUINAZOLINE DERIVATIVE;

ANALYSIS; ARTICLE; BINDING AFFINITY; MISSENSE MUTATION; MOLECULAR DOCKING; MUTANT; POINT MUTATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; COMPUTATIONAL BIOLOGY; DATABASES, PROTEIN; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MUTATION, MISSENSE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN KINASE INHIBITORS; PROTEIN STRUCTURE, SECONDARY; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SOFTWARE;

EID: 77949278284 PISSN: 02732289 EISSN: None Source Type: Journal
DOI: 10.1007/s12010-009-8662-4 Document Type: Article

Times cited : (13)

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