Involvement of an influx transporter in the blood-brain barrier transport of naloxone

Biopharmaceutics and Drug Disposition

Volumn 31, Issue 4, 2010, Pages 243-252

  Suzuki, Toyofumi ^a   Ohmuro, Aya ^a   Miyata, Mariko ^a   Furuishi, Takayuki ^a   Hidaka, Shinji ^a   Kugawa, Fumihiko ^b   Fukami, Toshiro ^a   Tomono, Kazuo ^a  

^a NIHON UNIVERSITY   (Japan)

^b HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

Blood brain barrier; Brain uptake index; Influx transport; Naloxone; Opioid antagonist

Indexed keywords

4 AMINOHIPPURIC ACID; CARNITINE; DIGOXIN; DIPHENHYDRAMINE; HISTAMINE H1 RECEPTOR ANTAGONIST; LIDOCAINE; MEPYRAMINE; NALOXONE; ORGANIC ANION TRANSPORTER; ORGANIC CATION TRANSPORTER; PENICILLIN G; PRAVASTATIN; PROPRANOLOL; TAUROCHOLIC ACID; TETRYLAMMONIUM; THIONEINE; TRITIUM; CATION; NARCOTIC ANTAGONIST;

ACTIVE TRANSPORT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DIFFUSION; DRUG LABELING; DRUG TISSUE LEVEL; DRUG TRANSPORT; MALE; MICHAELIS CONSTANT; NONHUMAN; PASSIVE TRANSPORT; PH; RAT; ANIMAL; DIFFUSION; DOSE RESPONSE; FEMALE; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL; WISTAR RAT;

ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; BRAIN; CATIONS; DIFFUSION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HYDROGEN-ION CONCENTRATION; NALOXONE; NARCOTIC ANTAGONISTS; RATS; RATS, WISTAR;

EID: 77955285327     PISSN: 01422782     EISSN: 1099081X     Source Type: Journal    
DOI: 10.1002/bdd.707     Document Type: Article

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