Transporter-mediated permeation of drugs across the blood-brain barrier

Journal of Pharmaceutical Sciences

Volumn 89, Issue 11, 2000, Pages 1371-1388

  Tamai, Ikumi ^b   Tsuji, Akira ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b NONE

Author keywords

Blood brain barrier, BBB; Central nervous system, CNS; Multidrug resistance associated protein, MRP; P glycoprotein, P gp; Tetraethylammonium, TEA

Indexed keywords

4 ACETAMIDO 4' ISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; 4 AMINOHIPPURIC ACID; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; 5 AMINO 7 (7 AMINO 5 AZASPIRO[2.4]HEPT 5 YL) 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 8 METHYL 4 OXO 3 QUINOLINECARBOXYLIC ACID; ANTINEOPLASTIC AGENT; BENZOIC ACID; BROMSULFOPHTHALEIN; CARBOXYLIC ACID; CATION; CIMETIDINE; CYCLOSPORIN A; ENOXACIN; GLYCOPROTEIN P; GREPAFLOXACIN; LEVOFLOXACIN; LOMEFLOXACIN; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN; N METHYLNICOTINAMIDE; NORFLOXACIN; OFLOXACIN; PENICILLIN G; PHENYLGLYOXAL; PROBENECID; QUINIDINE; QUINOLONE DERIVATIVE; RESERPINE; SPARFLOXACIN; SULFINPYRAZONE; TETRYLAMMONIUM; TOSUFLOXACIN; UNINDEXED DRUG; VALPROIC ACID;

AMINO ACID TRANSPORT; BLOOD BRAIN BARRIER; BRAIN BLOOD FLOW; BRAIN CAPILLARY; CAPILLARY ENDOTHELIUM; CENTRAL NERVOUS SYSTEM; DRUG DISTRIBUTION; DRUG PENETRATION; HEXOSE TRANSPORT; NONHUMAN; NUCLEOSIDE TRANSPORT; PROTEIN TRANSPORT; SHORT SURVEY;

EID: 0033756459     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/1520-6017(200011)89:11<1371::AID-JPS1>3.0.CO;2-D     Document Type: Article

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