Contrasting transcriptional responses of a virulent and an attenuated strain of Mycobacterium tuberculosis infecting macrophages

PLoS ONE

Volumn 5, Issue 6, 2010, Pages

  Li, Alice H ^a,d   Waddell, Simon J ^c   Hinds, Jason ^c   Malloff, Chad A ^a   Bains, Manjeet ^a   Hancock, Robert E ^a   Lam, Wan L ^a   Butcher, Philip D ^c   Stokes, Richard W ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b BC CHILDREN S HOSPITAL   (Canada)

^c ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EARLY SECRETORY ANTIGENIC TARGET 6; FATTY ACID; GENOMIC DNA; MYCOBACTIN; RNA; SIDEROPHORE; UNCLASSIFIED DRUG;

ADAPTATION; ANIMAL CELL; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; BONE MARROW; CONTROLLED STUDY; FATTY ACID METABOLISM; GENE EXPRESSION PROFILING; GENE INDUCTION; GENE OVEREXPRESSION; HOST PATHOGEN INTERACTION; LIQUID CULTURE; MACROPHAGE; MICROARRAY ANALYSIS; MOUSE; MUTATIONAL ANALYSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTEIN SECRETION; REGULON; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; STRAIN DIFFERENCE; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS;

ANIMALS; CELLS, CULTURED; MACROPHAGES; MICE; MYCOBACTERIUM TUBERCULOSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION, GENETIC; VIRULENCE;

MURINAE; MYCOBACTERIUM TUBERCULOSIS;

EID: 77955255547     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011066     Document Type: Article

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