Absence of complement receptor 3 results in reduced binding and ingestion of Mycobacterium tuberculosis but has no significant effect on the induction of reactive oxygen and nitrogen intermediates or on the survival of the bacteria in resident and interferon-gamma activated macrophages

Microbial Pathogenesis

Volumn 39, Issue 3, 2005, Pages 57-67

  Rooyakkers, Amanda W J ^a   Stokes, Richard W ^a,b,c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b BC CHILDREN S HOSPITAL   (Canada)

^c CHILDREN S AND WOMEN S HEALTH CENTRE OF BRITISH COLUMBIA   (Canada)

Author keywords

Cell mediated immunity; Mycobacteria; Nitric oxide; Pathogenesis; Superoxide anion; Tuberculosis

Indexed keywords

CELL SURFACE RECEPTOR; COMPLEMENT RECEPTOR; COMPLEMENT RECEPTOR 3; GAMMA INTERFERON; OPSONIN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; BACTERIAL INFECTION; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; CELL INTERACTION; CONTROLLED STUDY; INGESTION; INHIBITION KINETICS; INTRACELLULAR KILLING; INTRACELLULAR SPACE; MACROPHAGE ACTIVATION; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RECEPTOR BINDING; SERUM;

ANIMALS; ENZYME INHIBITORS; FEMALE; INTERFERON TYPE II; MACROPHAGE ACTIVATION; MACROPHAGE-1 ANTIGEN; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYCOBACTERIUM TUBERCULOSIS; NITRIC OXIDE; OMEGA-N-METHYLARGININE; SPECIFIC PATHOGEN-FREE ORGANISMS; SUPEROXIDE DISMUTASE; SUPEROXIDES; TUBERCULOSIS;

CORYNEBACTERINEAE; MYCOBACTERIUM TUBERCULOSIS;

EID: 23944488210     PISSN: 08824010     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micpath.2005.05.001     Document Type: Article

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