메뉴 건너뛰기




Volumn 16, Issue 15, 2010, Pages 3887-3900

Effects of anti-VEGF treatment duration on tumor growth, tumor regrowth, and treatment efficacy

Author keywords

[No Author keywords available]

Indexed keywords

CARBOPLATIN; CISPLATIN; DOCETAXEL; DOXORUBICIN; FLUOROURACIL; GEMCITABINE; IRINOTECAN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY B20 4.1; MONOCLONAL ANTIBODY B20 4.1.1; PACLITAXEL; TAXANE DERIVATIVE; UNCLASSIFIED DRUG; VASCULOTROPIN ANTIBODY;

EID: 77955123285     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-09-3100     Document Type: Article
Times cited : (124)

References (48)
  • 1
    • 0000912662 scopus 로고
    • Vascularization of the Brown-Pearce rabbit epithelioma transplant as seen in the transparent ear chamber
    • Ide AG, Baker NH, Warren SL. Vascularization of the Brown-Pearce rabbit epithelioma transplant as seen in the transparent ear chamber. Am J Roentgenol 1939;42:891-9.
    • (1939) Am J Roentgenol , vol.42 , pp. 891-899
    • Ide, A.G.1    Baker, N.H.2    Warren, S.L.3
  • 2
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971;285:1182-6.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 3
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Sciences (New York) 1989;246:1306-9. (Pubitemid 20066716)
    • (1989) Science , vol.246 , Issue.4935 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.-J.3    Goeddel, D.V.4    Ferrara, N.5
  • 4
    • 0025194878 scopus 로고
    • 2-terminal amino acid sequence of guinea pig tumor-secreted vascular permeability factor
    • Senger DR, Connolly DT, Van de Water L, Feder J, Dvorak HF. Purification and NH2-terminal amino acid sequence of guinea pig tumor-secreted vascular permeability factor. Cancer Res 1990;50:1774-8. (Pubitemid 20098819)
    • (1990) Cancer Research , vol.50 , Issue.6 , pp. 1774-1778
    • Senger, D.R.1    Connolly, D.T.2    Van De Water, L.3    Feder, J.4    Dvorak, H.F.5
  • 5
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004;350:2335-42.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 6
    • 37349124748 scopus 로고    scopus 로고
    • Bevacizumab: Optimal dose, schedule, and duration of therapy
    • Gandara DR, Sangha R, Davies AM. Bevacizumab: optimal dose, schedule, and duration of therapy. Clin Lung Cancer 2007;8:522-3. (Pubitemid 350292219)
    • (2007) Clinical Lung Cancer , vol.8 , Issue.9 , pp. 522-523
    • Gandara, D.R.1    Sangha, R.2    Davies, A.M.3
  • 7
    • 33845961014 scopus 로고    scopus 로고
    • Bevacizumab: An angiogenesis inhibitor for the treatment of solid malignancies
    • Shih T, Lindley C. Bevacizumab: an angiogenesis inhibitor for the treatment of solid malignancies. Clin Ther 2006;28:1779-802.
    • (2006) Clin Ther , vol.28 , pp. 1779-1802
    • Shih, T.1    Lindley, C.2
  • 8
    • 33748446259 scopus 로고    scopus 로고
    • Lack of benefit of maintenance paclitaxel in first-line chemotherapy in metastatic breast cancer
    • Gennari A, Amadori D, De Lena M, et al. Lack of benefit of maintenance paclitaxel in first-line chemotherapy in metastatic breast cancer. J Clin Oncol 2006;24:3912-8.
    • (2006) J Clin Oncol , vol.24 , pp. 3912-3918
    • Gennari, A.1    Amadori, D.2    De Lena, M.3
  • 9
    • 0036499649 scopus 로고    scopus 로고
    • Phase III trial comparing a defined duration of therapy versus continuous therapy followed by second-line therapy in advanced-stage IIIB/IV non-small-cell lung cancer
    • Socinski MA, Schell MJ, Peterman A, et al. Phase III trial comparing a defined duration of therapy versus continuous therapy followed by second-line therapy in advanced-stage IIIB/IV non-small-cell lung cancer. J Clin Oncol 2002;20:1335-43.
    • (2002) J Clin Oncol , vol.20 , pp. 1335-1343
    • Socinski, M.A.1    Schell, M.J.2    Peterman, A.3
  • 10
    • 42949149159 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized phase III study
    • Saltz LB, Clarke S, Diaz-Rubio E, et al. Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 2008;26:2013-9.
    • (2008) J Clin Oncol , vol.26 , pp. 2013-2019
    • Saltz, L.B.1    Clarke, S.2    Diaz-Rubio, E.3
  • 11
    • 33846149645 scopus 로고    scopus 로고
    • AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
    • Batchelor TT, Sorensen AG, di Tomaso E, et al. AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell 2007;11:83-95.
    • (2007) Cancer Cell , vol.11 , pp. 83-95
    • Batchelor, T.T.1    Sorensen, A.G.2    Di Tomaso, E.3
  • 12
    • 50849089255 scopus 로고    scopus 로고
    • Reversible tumor growth acceleration following bevacizumab interruption in metastatic colorectal cancer patients scheduled for surgery
    • Cacheux W, Boisserie T, Staudacher L, et al. Reversible tumor growth acceleration following bevacizumab interruption in metastatic colorectal cancer patients scheduled for surgery. Ann Oncol 2008;19:1659-61.
    • (2008) Ann Oncol , vol.19 , pp. 1659-1661
    • Cacheux, W.1    Boisserie, T.2    Staudacher, L.3
  • 13
    • 55049137067 scopus 로고    scopus 로고
    • Tumor growth rates derived from data for patients in a clinical trial correlate strongly with patient survival: A novel strategy for evaluation of clinical trial data
    • Stein WD, Figg WD, Dahut W, et al. Tumor growth rates derived from data for patients in a clinical trial correlate strongly with patient survival: a novel strategy for evaluation of clinical trial data. Oncologist 2008;13:1046-54.
    • (2008) Oncologist , vol.13 , pp. 1046-1054
    • Stein, W.D.1    Figg, W.D.2    Dahut, W.3
  • 14
    • 55049109179 scopus 로고    scopus 로고
    • Bevacizumab reduces the growth rate constants of renal carcinomas: A novel algorithm suggests early discontinuation of bevacizumab resulted in a lack of survival advantage
    • Stein WD, Yang J, Bates SE, Fojo T. Bevacizumab reduces the growth rate constants of renal carcinomas: a novel algorithm suggests early discontinuation of bevacizumab resulted in a lack of survival advantage. Oncologist 2008;13:1055-62.
    • (2008) Oncologist , vol.13 , pp. 1055-1062
    • Stein, W.D.1    Yang, J.2    Bates, S.E.3    Fojo, T.4
  • 15
    • 62649101158 scopus 로고    scopus 로고
    • Cancer: The nuances of therapy
    • Ellis LM, Reardon DA. Cancer: the nuances of therapy. Nature 2009; 458:290-2.
    • (2009) Nature , vol.458 , pp. 290-292
    • Ellis, L.M.1    Reardon, D.A.2
  • 16
    • 57649135172 scopus 로고    scopus 로고
    • A role for VEGF as a negative regulator of pericyte function and vessel maturation
    • Greenberg JI, Shields DJ, Barillas SG, et al. A role for VEGF as a negative regulator of pericyte function and vessel maturation. Nature 2008;456:809-13.
    • (2008) Nature , vol.456 , pp. 809-813
    • Greenberg, J.I.1    Shields, D.J.2    Barillas, S.G.3
  • 17
    • 60649106195 scopus 로고    scopus 로고
    • Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
    • Paez-Ribes M, Allen E, Hudock J, et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 2009;15:220-31.
    • (2009) Cancer Cell , vol.15 , pp. 220-231
    • Paez-Ribes, M.1    Allen, E.2    Hudock, J.3
  • 18
    • 57649112725 scopus 로고    scopus 로고
    • Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis
    • Stockmann C, Doedens A, Weidemann A, et al. Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis. Nature 2008;456:814-8.
    • (2008) Nature , vol.456 , pp. 814-818
    • Stockmann, C.1    Doedens, A.2    Weidemann, A.3
  • 19
    • 33749441325 scopus 로고    scopus 로고
    • Rapid vascular regrowth in tumors after reversal of VEGF inhibition
    • Mancuso MR, Davis R, Norberg SM, et al. Rapid vascular regrowth in tumors after reversal of VEGF inhibition. J Clin Invest 2006;116:2610-21.
    • (2006) J Clin Invest , vol.116 , pp. 2610-2621
    • Mancuso, M.R.1    Davis, R.2    Norberg, S.M.3
  • 20
    • 33644863498 scopus 로고    scopus 로고
    • Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF
    • Liang WC, Wu X, Peale FV, et al. Cross-species vascular endothelial growth factor (VEGF)-blocking antibodies completely inhibit the growth of human tumor xenografts and measure the contribution of stromal VEGF. J Biol Chem 2006;281:951-61.
    • (2006) J Biol Chem , vol.281 , pp. 951-961
    • Liang, W.C.1    Wu, X.2    Peale, F.V.3
  • 21
    • 0032931234 scopus 로고    scopus 로고
    • VEGF is required for growth and survival in neonatal mice
    • Gerber HP, Hillan KJ, Ryan AM, et al. VEGF is required for growth and survival in neonatal mice. Development 1999;126:1149-59.
    • (1999) Development , vol.126 , pp. 1149-1159
    • Gerber, H.P.1    Hillan, K.J.2    Ryan, A.M.3
  • 22
    • 4043083699 scopus 로고    scopus 로고
    • Human endocrine gland-derived vascular endothelial growth factor: Expression early in development and in Leydig cell tumors suggests roles in normal and pathological testis angiogenesis
    • DOI 10.1210/jc.2003-032024
    • Samson M, Peale F, Frantz G, Rioux-Leclercq N, Rajpert-De Meyts E, Ferrara N. Human endocrine gland-derived vascular endothelial growth factor: expression early in development and in Leydig cell tumors suggests roles in normal and pathological testis angiogenesis. J Clin Endocrinol Metab 2004;89:4078-88. (Pubitemid 39071516)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.8 , pp. 4078-4088
    • Samson, M.1    Peale Jr., F.V.2    Frantz, G.3    Rioux-Leclercq, N.4    Rajpert-De Meyts, E.5    Ferrara, N.6
  • 23
    • 57749173152 scopus 로고    scopus 로고
    • VEGF inhibition: Insights from preclinical and clinical studies
    • Crawford Y, Ferrara N. VEGF inhibition: insights from preclinical and clinical studies. Cell Tissue Res 2009;335:261-9.
    • (2009) Cell Tissue Res , vol.335 , pp. 261-269
    • Crawford, Y.1    Ferrara, N.2
  • 24
    • 0033018871 scopus 로고    scopus 로고
    • Efficacy and concentration-response of murine anti-VEGF monoclonal antibody in tumor-bearing mice and extrapolation to humans
    • Mordenti J, Thomsen K, Licko V, Chen H, Meng YG, Ferrara N. Efficacy and concentration-response of murine anti-VEGF monoclonal antibody in tumor-bearing mice and extrapolation to humans. Toxicol Pathol 1999;27:14-21. (Pubitemid 29075738)
    • (1999) Toxicologic Pathology , vol.27 , Issue.1 , pp. 14-21
    • Mordenti, J.1    Thomsen, K.2    Licko, V.3    Chen, H.4    Meng, Y.G.5    Ferrara, N.6
  • 26
    • 0000391746 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
    • Bergers G, Brekken R, McMahon G, et al. Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat Cell Biol 2000;2:737-44.
    • (2000) Nat Cell Biol , vol.2 , pp. 737-744
    • Bergers, G.1    Brekken, R.2    McMahon, G.3
  • 27
    • 77549088772 scopus 로고    scopus 로고
    • Pathways mediating VEGF-independent tumor angiogenesis
    • Ferara N. Pathways mediating VEGF-independent tumor angiogenesis. Cytokine Growth Factor Rev 2010;21:21-6.
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 21-26
    • Ferara, N.1
  • 28
    • 40649104348 scopus 로고    scopus 로고
    • Role of Bv8 in neutrophil-dependent angiogenesis in a transgenic model of cancer progression
    • Shojaei F, Singh M, Thompson JD, Ferrara N. Role of Bv8 in neutrophil-dependent angiogenesis in a transgenic model of cancer progression. Proc Natl Acad Sci U S A 2008;105:2640-5.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 2640-2645
    • Shojaei, F.1    Singh, M.2    Thompson, J.D.3    Ferrara, N.4
  • 29
    • 36849013036 scopus 로고    scopus 로고
    • Bv8 regulates myeloid-cell-dependent tumour angiogenesis
    • Shojaei F, Wu X, Zhong C, et al. Bv8 regulates myeloid-cell-dependent tumour angiogenesis. Nature 2007;450:825-31.
    • (2007) Nature , vol.450 , pp. 825-831
    • Shojaei, F.1    Wu, X.2    Zhong, C.3
  • 30
    • 33746860827 scopus 로고    scopus 로고
    • Angiogenesis in colorectal cancer: Prognostic and therapeutic implications
    • Giatromanolaki A, Sivridis E, Koukourakis MI. Angiogenesis in colorectal cancer: prognostic and therapeutic implications. Am J Clin Oncol 2006;29:408-17.
    • (2006) Am J Clin Oncol , vol.29 , pp. 408-417
    • Giatromanolaki, A.1    Sivridis, E.2    Koukourakis, M.I.3
  • 31
    • 33744962527 scopus 로고    scopus 로고
    • Clinical implications of angiogenesis in cancers
    • Pang RW, Poon RT. Clinical implications of angiogenesis in cancers. Vasc Health Risk Manag 2006;2:97-108.
    • (2006) Vasc Health Risk Manag , vol.2 , pp. 97-108
    • Pang, R.W.1    Poon, R.T.2
  • 32
    • 67650380136 scopus 로고    scopus 로고
    • Biomarkers of response and resistance to antiangiogenic therapy
    • Jain RK, Duda DG, Willett CG, et al. Biomarkers of response and resistance to antiangiogenic therapy. Nat Rev Clin Oncol 2009;6: 327-38.
    • (2009) Nat Rev Clin Oncol , vol.6 , pp. 327-338
    • Jain, R.K.1    Duda, D.G.2    Willett, C.G.3
  • 33
    • 34248386965 scopus 로고    scopus 로고
    • Challenges for patient selection with VEGF inhibitors
    • Longo R, Gasparini G. Challenges for patient selection with VEGF inhibitors. Cancer Chemother Pharmacol 2007;60:151-70.
    • (2007) Cancer Chemother Pharmacol , vol.60 , pp. 151-170
    • Longo, R.1    Gasparini, G.2
  • 34
    • 40749125285 scopus 로고    scopus 로고
    • Sustained VEGF blockade results in microenvironmental sequestration of VEGF by tumors and persistent VEGF receptor-2 activation
    • Kadenhe-Chiweshe A, Papa J, McCrudden KW, et al. Sustained VEGF blockade results in microenvironmental sequestration of VEGF by tumors and persistent VEGF receptor-2 activation. Mol Cancer Res 2008;6:1-9.
    • (2008) Mol Cancer Res , vol.6 , pp. 1-9
    • Kadenhe-Chiweshe, A.1    Papa, J.2    McCrudden, K.W.3
  • 35
    • 34548217651 scopus 로고    scopus 로고
    • Maximizing mouse cancer models
    • Frese KK, Tuveson DA. Maximizing mouse cancer models. Nat Rev Cancer 2007;7:645-58.
    • (2007) Nat Rev Cancer , vol.7 , pp. 645-658
    • Frese, K.K.1    Tuveson, D.A.2
  • 36
    • 64249114690 scopus 로고    scopus 로고
    • The use of GEM models for experimental cancer therapeutics
    • Gopinathan A, Tuveson DA. The use of GEM models for experimental cancer therapeutics. Dis Model Mech 2008;1:83-6.
    • (2008) Dis Model Mech , vol.1 , pp. 83-86
    • Gopinathan, A.1    Tuveson, D.A.2
  • 37
    • 0033617532 scopus 로고    scopus 로고
    • Effects of angiogenesis inhibitors on multistage carcinogenesis in mice
    • New York
    • Bergers G, Javaherian K, Lo KM, Folkman J, Hanahan D. Effects of angiogenesis inhibitors on multistage carcinogenesis in mice. Sciences (New York) 1999;284:808-12.
    • (1999) Sciences , vol.284 , pp. 808-812
    • Bergers, G.1    Javaherian, K.2    Lo, K.M.3    Folkman, J.4    Hanahan, D.5
  • 38
    • 33646586669 scopus 로고    scopus 로고
    • Preclinical activity of ABT-869, a multitargeted receptor tyrosine kinase inhibitor
    • Albert DH, Tapang P, Magoc TJ, et al. Preclinical activity of ABT-869, a multitargeted receptor tyrosine kinase inhibitor. Mol Cancer Ther 2006;5:995-1006.
    • (2006) Mol Cancer Ther , vol.5 , pp. 995-1006
    • Albert, D.H.1    Tapang, P.2    Magoc, T.J.3
  • 39
    • 57849106330 scopus 로고    scopus 로고
    • PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment
    • Crawford Y, Kasman I, Yu L, et al. PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. Cancer Cell 2009;15:21-34.
    • (2009) Cancer Cell , vol.15 , pp. 21-34
    • Crawford, Y.1    Kasman, I.2    Yu, L.3
  • 40
    • 52649150833 scopus 로고    scopus 로고
    • Targeting angiogenesis driven by vascular endothelial growth factors using antibody-based therapies
    • Grothey A, Ellis L. Targeting angiogenesis driven by vascular endothelial growth factors using antibody-based therapies. Cancer J 2008;14:170-7.
    • (2008) Cancer J , vol.14 , pp. 170-177
    • Grothey, A.1    Ellis, L.2
  • 41
    • 21244450758 scopus 로고    scopus 로고
    • Association of k-ras, b-raf, and p53 status with the treatment effect of bevacizumab
    • Ince WL, Jubb A, Holden SN, et al. Association of k-ras, b-raf, and p53 status with the treatment effect of bevacizumab. J Natl Cancer Inst 2005;97:981-9.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 981-989
    • Ince, W.L.1    Jubb, A.2    Holden, S.N.3
  • 42
    • 70350721785 scopus 로고    scopus 로고
    • Quantifying antivascular effects of monoclonal antibodies to vascular endothelial growth factor
    • O'Connor J, Carano R, Clamp A, et al. Quantifying antivascular effects of monoclonal antibodies to vascular endothelial growth factor. Clin Cancer Res 2009;15:6674-82.
    • (2009) Clin Cancer Res , vol.15 , pp. 6674-6682
    • O'Connor, J.1    Carano, R.2    Clamp, A.3
  • 43
    • 59449084872 scopus 로고    scopus 로고
    • Maintenance treatment with bevacizumab prolongs survival in an in vivo ovarian cancer model
    • Mabuchi S, Terai Y, Morishige K, et al. Maintenance treatment with bevacizumab prolongs survival in an in vivo ovarian cancer model. Clin Cancer Res 2008;14:7781-9.
    • (2008) Clin Cancer Res , vol.14 , pp. 7781-7789
    • Mabuchi, S.1    Terai, Y.2    Morishige, K.3
  • 44
    • 0034894341 scopus 로고    scopus 로고
    • Combination antiangiogenic therapy: Increased efficacy in a murine model of Wilms tumor
    • Soffer SZ, Moore JT, Kim E, et al. Combination antiangiogenic therapy: increased efficacy in a murine model of Wilms tumor. J Pediatr Surg 2001;36:1177-81.
    • (2001) J Pediatr Surg , vol.36 , pp. 1177-1181
    • Soffer, S.Z.1    Moore, J.T.2    Kim, E.3
  • 45
    • 58149521889 scopus 로고    scopus 로고
    • In vivo activity of novel capecitabine regimens alone and with bevacizumab and oxaliplatin in colorectal cancer xenograft models
    • Kolinsky K, Shen BQ, Zhang YE, et al. In vivo activity of novel capecitabine regimens alone and with bevacizumab and oxaliplatin in colorectal cancer xenograft models. Mol Cancer Ther 2009;8:75-82.
    • (2009) Mol Cancer Ther , vol.8 , pp. 75-82
    • Kolinsky, K.1    Shen, B.Q.2    Zhang, Y.E.3
  • 46
    • 57349110570 scopus 로고    scopus 로고
    • Combining bevacizumab with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model
    • Mathieu V, De Nève N, Le Mercier M, et al. Combining bevacizumab with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model. NEO 2008;10: 1383-92.
    • (2008) NEO , vol.10 , pp. 1383-1392
    • Mathieu, V.1    De Nève, N.2    Le Mercier, M.3
  • 47
    • 60649116477 scopus 로고    scopus 로고
    • Silencing or fueling metastasis with VEGF inhibitors: Antiangiogenesis revisited
    • Loges S, Mazzone M, Hohensinner P, Carmeliet P. Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited. Cancer Cell 2009;15:167-70.
    • (2009) Cancer Cell , vol.15 , pp. 167-170
    • Loges, S.1    Mazzone, M.2    Hohensinner, P.3    Carmeliet, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.