Efficacy and concentration-response of murine anti-VEGF monoclonal antibody in tumor-bearing mice and extrapolation to humans

Toxicologic Pathology

Volumn 27, Issue 1, 1999, Pages 14-21

  Mordenti, Joyce ^a,b   Thomsen, Karen ^a   Licko, Vojtech ^a   Chen, Helen ^a   Meng, Y Gloria ^a   Ferrara, Napoleone ^a  

^a GENENTECH INC   (United States)

^b Axys Pharmaceuticals Inc   (United States)

Author keywords

Angiogenesis; Pharmacodynamics; Pharmacokinetics; Tumor growth dynamics; Tumorigenesis

Indexed keywords

MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HUMAN; HUMAN TISSUE; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; RHABDOMYOSARCOMA; TUMOR VASCULARIZATION;

ANIMALIA; MURINAE; MUS MUSCULUS;

EID: 0033018871     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/019262339902700104     Document Type: Conference Paper

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