Trigenic neural crest-restricted Smad7 over-expression results in congenital craniofacial and cardiovascular defects

Developmental Biology

Volumn 344, Issue 1, 2010, Pages 233-247

  Tang, Sunyong ^a   Snider, Paige ^a   Firulli, Antony B ^a   Conway, Simon J ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Endocardial cushions; Facial cleft; Heart development; Mouse embryo; Neural crest; Reverse tetracycline transactivator; Smad7; Tetracycline responsive element driven transgenes

Indexed keywords

BONE MORPHOGENETIC PROTEIN; DOXYCYCLINE; SMAD1 PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD5 PROTEIN; SMAD7 PROTEIN; SMAD8 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CONGENITAL HEART DISEASE; CONTROLLED STUDY; CRANIOFACIAL DEVELOPMENT; CRANIOFACIAL MALFORMATION; EMBRYO; FEMALE; GENE OVEREXPRESSION; HEART DEVELOPMENT; HEART VENTRICLE SEPTUM DEFECT; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEURAL CREST; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RNA ANALYSIS; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER;

EID: 77955054236     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2010.05.004     Document Type: Article

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