Inactivation of TGFβ signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome

Genes and Development

Volumn 19, Issue 5, 2005, Pages 530-535

  Wurdak, Heiko ^a   Ittner, Lars M ^b   Lang, Karl S ^c   Leveen, Per ^d   Suter, Ueli ^a   Fischer, Jan A ^b   Karlsson, Stefan ^d   Born, Walter ^b   Sommer, Lukas ^a  

^a ETH ZURICH   (Switzerland)

^b BALGRIST UNIVERSITY HOSPITAL   (Switzerland)

^c INSTITUTE OF EXPERIMENTAL IMMUNOLOGY   (Switzerland)

^d LUND UNIVERSITY   (Sweden)

Author keywords

CrkL; DiGeorge syndrome; Fate decision; Neural crest; Pharyngeal apparatus; Src kinase; TGF

Indexed keywords

CRE RECOMBINASE; CRK LIKE PROTEIN; SMAD2 PROTEIN; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; WNT PROTEIN; NUCLEAR PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR MALFORMATION; CELL MIGRATION; CHROMOSOME 22; CONTROLLED STUDY; CRANIOFACIAL MALFORMATION; DIGEORGE SYNDROME; EMBRYO; EXPLANT; GENE DELETION; GENETIC MANIPULATION; MOUSE; NEURAL CREST CELL; NONHUMAN; PARATHYROID DISEASE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; THYMUS ATROPHY; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MOUSE MUTANT; NEURAL CREST; PHOSPHORYLATION; PHYSIOLOGY; STEM CELL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL DIFFERENTIATION; DIGEORGE SYNDROME; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MICE; MICE, KNOCKOUT; NEURAL CREST; NUCLEAR PROTEINS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STEM CELLS; TRANSFORMING GROWTH FACTOR BETA;

EID: 14644418529     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.317405     Document Type: Article

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