Instructive Role of Wnt/β-Catenin in Sensory Fate Specification in Neural Crest Stem Cells

Science

Volumn 303, Issue 5660, 2004, Pages 1020-1023

  Lee, Hye Youn ^a   Kléber, Maurice ^a   Hari, Lisette ^a   Brault, Véronique ^b,d   Suter, Ueli ^a   Taketo, Makoto M ^c   Kemler, Rolf ^b   Sommer, Lukas ^a  

^a ETH ZURICH   (Switzerland)

^b MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^c KYOTO UNIVERSITY   (Japan)

^d Experimental and Molecular Genetics   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; MOLECULAR BIOLOGY;

NEURAL CREST DERIVATIVES; NEURAL CREST STEM CELLS (NCSC);

NEUROLOGY;

BETA CATENIN; WNT PROTEIN;

BIOLOGY;

ARTICLE; CELL TYPE; CONTROL SYSTEM; NEURAL CREST; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN STABILITY; REGULATORY MECHANISM; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BETA CATENIN; CADHERINS; CELL DIFFERENTIATION; CELL DIVISION; CELL LINEAGE; CELL MOVEMENT; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; MICE; MODELS, NEUROLOGICAL; MULTIPOTENT STEM CELLS; MUTATION; NERVE TISSUE PROTEINS; NEURAL CREST; NEURONS, AFFERENT; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION FACTOR BRN-3; TRANSCRIPTION FACTORS; WNT PROTEINS; WNT1 PROTEIN; ZEBRAFISH PROTEINS;

EID: 1142298447     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1091611     Document Type: Article

References (32)

1. K. Willert et al., Nature 423, 448 (2003).
2. M. van de Wetering et al., Cell 111, 241 (2002).
3. T. Reya et al., Nature 423, 409 (2003).
4. K. M. Cadigan, R. Nusse, Genes Dev. 11, 3286 (1997).
5. S. G. Megason, A. P. McMahon, Development 129, 2087 (2002).
6. A. Chenn, C. A. Walsh, Science 297, 365 (2002).
7. N. M. Le Douarin, C. Kalcheim, The Neural Crest (Cambridge Univ. Press, Cambridge, UK, ed. 2, 1999).
8. R. I. Dorsky, R. T. Moon, D. W. Raible, Bioessays 22, 708 (2000).
9. M. I. Garcia-Castro, C. Marcelle, M. Bronner-Fraser, Science 297, 848 (2002).
10. M. Ikeya, S. M. Lee, J. E. Johnson, A. P. McMahon, S. Takada, Nature 389, 966 (1997).
11. L. Hari et al., J. Cell Biol. 159, 867 (2002).
12. N. Harada et al., EMBO J. 18, 5931 (1999).
13. Materials and methods are available as supporting material on Science Online.
14. D. M. Noden, J. Neurobiol. 24, 248 (1993).
15. Y. Chai et al., Development 127, 1671 (2000).
16. H. C. Etchevers, C. Vincent, N. M. Le Douarin, G. F. Couly, Development 128, 1059 (2001).
17. M. L. Kirby, K. L. Waldo, Circ. Res. 77, 211 (1995).
18. X. Jiang, D. H. Rowitch, P. Soriano, A. P. McMahon, H. M. Sucov, Development 127, 1607 (2000).
19. H.-Y. Lee, M. Kleber, L. Sommer, data not shown.
20. M. Zirlinger, L. Lo, J. McMahon, A. P. McMahon, D. J. Anderson, Proc. Natl. Acad. Sci. U.S.A. 99, 8084 (2002).
21. C. Paratore, D. E. Goerich, U. Suter, M. Wegner, L. Sommer, Development 128, 3949 (2001).
22. J. Kim, L. Lo, E. Dormand, D. J. Anderson, Neuron 38, 17 (2003).
23. C. Paratore, C. Eichenberger, U. Suter, L. Sommer, Hum. Mol. Genet. 11, 3075 (2002).
24. V. Brault et al., Development 128, 12S3 (2001).
25. M. Sieber-Blum, Science 243, 1608 (1989).
26. A. L. Greenwood, E. E. Turner, D. J. Anderson, Development 126, 3S4S (1999).
27. A. Baroffio, E. Dupin, N. M. Le Douarin, Development 112, 301 (1991).
28. M. Bronner-Fraser, S. Fraser, Neuron 3, 7SS (1989).
29. E. Frank, J. R. Sanes, Development 111, 89S (1991).
30. S. E. Fraser, M. E. Bronner-Fraser, Development 112, 913 (1991).
31. N. Shah, A. Groves, D. J. Anderson, Cell 85, 331 (1996).
32. Supported by grants of the Swiss National Science Foundation (to L.S. and U.S.) and by the National Center of Competence in Research "Neural Plasticity and Repair," We thank N. Mantei and R. Cassada for critical reading of the manuscript, A. McMahon and A. Berns for providing transgenic animals, and E. Ehler for advice with confocal microscopy, We acknowledge M. Wegner and J. Lee for riboprobes, and M. Wegner and E. Turner for antibodies.