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Volumn 22, Issue 8, 2010, Pages 681-691

B-cell homeostasis requires complementary CD22 and BLyS/BR3 survival signals

Author keywords

B cell depletion; B cell homeostasis; BLyS BAFF; CD22; mAb therapy

Indexed keywords

B CELL ACTIVATING FACTOR; B CELL ACTIVATING FACTOR RECEPTOR; B CELL ACTIVATING FACTOR RECEPTOR 3; CASPASE 3; CD22 ANTIGEN; CD40 ANTIGEN; IMMUNOGLOBULIN M ANTIBODY; MESSENGER RNA; MONOCLONAL ANTIBODY; PROTEIN BCL XL; UNCLASSIFIED DRUG;

EID: 77955027018     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxq055     Document Type: Article
Times cited : (7)

References (52)
  • 1
    • 0030993376 scopus 로고    scopus 로고
    • CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling
    • Tedder, T. F., Tuscano, J., Sato, S. and Kehrl, J. H. 1997. CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling. Annu. Rev. Immunol. 15:481.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 481
    • Tedder, T.F.1    Tuscano, J.2    Sato, S.3    Kehrl, J.H.4
  • 3
    • 0032522626 scopus 로고    scopus 로고
    • Bcmd decreases the life span of B-2 but not B-1 cells in A/WySnJ mice
    • Lentz, V. M., Hayes, C. E. and Cancro, M. P. 1998. Bcmd decreases the life span of B-2 but not B-1 cells in A/WySnJ mice. J. Immunol. 160:3743.
    • (1998) J. Immunol. , vol.160 , pp. 3743
    • Lentz, V.M.1    Hayes, C.E.2    Cancro, M.P.3
  • 4
    • 0035846593 scopus 로고    scopus 로고
    • Competition for BLyS-mediated signaling through Bcmd/BR3 regulates peripheral B lymphocyte numbers
    • Harless, S. M., Lentz, V. M., Sah, A. P. et al. 2001. Competition for BLyS-mediated signaling through Bcmd/BR3 regulates peripheral B lymphocyte numbers. Curr. Biol. 11:1986.
    • (2001) Curr. Biol. , vol.11 , pp. 1986
    • Harless, S.M.1    Lentz, V.M.2    Sah, A.P.3
  • 5
    • 0035860559 scopus 로고    scopus 로고
    • An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway
    • Schiemann, B., Gommerman, J. L., Vora, K. et al. 2001. An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway. Science 293:2111.
    • (2001) Science , vol.293 , pp. 2111
    • Schiemann, B.1    Gommerman, J.L.2    Vora, K.3
  • 6
    • 0028961779 scopus 로고
    • CD40 and its ligand: central players in B lymphocyte survival, growth, and differentiation
    • Gordon, J. 1995. CD40 and its ligand: central players in B lymphocyte survival, growth, and differentiation. Blood Rev. 9:53.
    • (1995) Blood Rev , vol.9 , pp. 53
    • Gordon, J.1
  • 7
    • 0028447437 scopus 로고
    • The immune responses in the CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation
    • Kawabe, T., Naka, T., Yoshida, K. et al. 1994. The immune responses in the CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation. Immunity 1:167.
    • (1994) Immunity , vol.1 , pp. 167
    • Kawabe, T.1    Naka, T.2    Yoshida, K.3
  • 8
    • 0342711256 scopus 로고    scopus 로고
    • In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
    • Lam, K. P., Kuhn, R. and Rajewsky, K. 1997. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death. Cell 90:1073.
    • (1997) Cell , vol.90 , pp. 1073
    • Lam, K.P.1    Kuhn, R.2    Rajewsky, K.3
  • 9
    • 0030499431 scopus 로고    scopus 로고
    • CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice
    • Sato, S., Miller, A. S., Inaoki, M. et al. 1996. CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. Immunity 5:551.
    • (1996) Immunity , vol.5 , pp. 551
    • Sato, S.1    Miller, A.S.2    Inaoki, M.3
  • 10
    • 0030467610 scopus 로고    scopus 로고
    • CD22 regulates thymus-independent responses and the lifespan of B cells
    • Otipoby, K. L., Andersson, K. B., Draves, K. E. et al. 1996. CD22 regulates thymus-independent responses and the lifespan of B cells. Nature 384:634.
    • (1996) Nature , vol.384 , pp. 634
    • Otipoby, K.L.1    Andersson, K.B.2    Draves, K.E.3
  • 12
    • 5444234832 scopus 로고    scopus 로고
    • CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms
    • Poe, J. C., Fujimoto, Y., Hasegawa, M. et al. 2004. CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms. Nat. Immunol. 5:1078.
    • (2004) Nat. Immunol. , vol.5 , pp. 1078
    • Poe, J.C.1    Fujimoto, Y.2    Hasegawa, M.3
  • 13
    • 33747752856 scopus 로고    scopus 로고
    • CD22 ligand binding regulates normal and malignant B lymphocyte survival in vivo
    • Haas, K. M., Sen, S., Sanford, I. G., Miller, A. S., Poe, J. C. and Tedder, T. F. 2006. CD22 ligand binding regulates normal and malignant B lymphocyte survival in vivo. J. Immunol. 177:3063.
    • (2006) J. Immunol. , vol.177 , pp. 3063
    • Haas, K.M.1    Sen, S.2    Sanford, I.G.3    Miller, A.S.4    Poe, J.C.5    Tedder, T.F.6
  • 14
    • 0033179893 scopus 로고    scopus 로고
    • Modulation of B lymphocyte antigen receptor signal transduction by a CD19/CD22 regulatory loop
    • Fujimoto, M., Bradney, A. P., Poe, J. C., Steeber, D. A. and Tedder, T. F. 1999. Modulation of B lymphocyte antigen receptor signal transduction by a CD19/CD22 regulatory loop. Immunity 11:191.
    • (1999) Immunity , vol.11 , pp. 191
    • Fujimoto, M.1    Bradney, A.P.2    Poe, J.C.3    Steeber, D.A.4    Tedder, T.F.5
  • 15
    • 58549086734 scopus 로고    scopus 로고
    • The BLyS family: toward a molecular understanding of B cell homeostasis
    • Treml, J. F., Hao, Y., Stadanlick, J. E. and Cancro, M. P. 2009. The BLyS family: toward a molecular understanding of B cell homeostasis. Cell Biochem. Biophys. 53:1.
    • (2009) Cell Biochem. Biophys. , vol.53 , pp. 1
    • Treml, J.F.1    Hao, Y.2    Stadanlick, J.E.3    Cancro, M.P.4
  • 16
    • 0033538468 scopus 로고    scopus 로고
    • BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator
    • Moore, P. A., Belvedere, O., Orr, A. et al. 1999. BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science 285:260.
    • (1999) Science , vol.285 , pp. 260
    • Moore, P.A.1    Belvedere, O.2    Orr, A.3
  • 17
    • 0033532634 scopus 로고    scopus 로고
    • BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth
    • Schneider, P., MacKay, F., Steiner, V. et al. 1999. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J. Exp. Med. 189:1747.
    • (1999) J. Exp. Med. , vol.189 , pp. 1747
    • Schneider, P.1    MacKay, F.2    Steiner, V.3
  • 18
    • 0034232338 scopus 로고    scopus 로고
    • Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity
    • Yan, M., Marsters, S. A., Grewal, I. S., Wang, H., Ashkenazi, A. and Dixit, V. M. 2000. Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity. Nat. Immunol. 1:37.
    • (2000) Nat. Immunol. , vol.1 , pp. 37
    • Yan, M.1    Marsters, S.A.2    Grewal, I.S.3    Wang, H.4    Ashkenazi, A.5    Dixit, V.M.6
  • 19
    • 0034634625 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS
    • Wu, Y., Bressette, D., Carrell, J. A. et al. 2000. Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS. J. Biol. Chem. 275:35478.
    • (2000) J. Biol. Chem. , vol.275 , pp. 35478
    • Wu, Y.1    Bressette, D.2    Carrell, J.A.3
  • 20
    • 0034729769 scopus 로고    scopus 로고
    • Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI
    • Marsters, S. A., Yan, M., Pitti, R. M., Haas, P. E., Dixit, V. M. and Ashkenazi, A. 2000. Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI. Curr. Biol. 10:785.
    • (2000) Curr. Biol. , vol.10 , pp. 785
    • Marsters, S.A.1    Yan, M.2    Pitti, R.M.3    Haas, P.E.4    Dixit, V.M.5    Ashkenazi, A.6
  • 21
    • 0030014518 scopus 로고    scopus 로고
    • Bcmd governs recruitment of new B cells into the stable peripheral B cell pool in the A/WySnJ mouse
    • Lentz, V. M., Cancro, M. P., Nashold, F. E. and Hayes, C. E. 1996. Bcmd governs recruitment of new B cells into the stable peripheral B cell pool in the A/WySnJ mouse. J. Immunol. 157:598.
    • (1996) J. Immunol. , vol.157 , pp. 598
    • Lentz, V.M.1    Cancro, M.P.2    Nashold, F.E.3    Hayes, C.E.4
  • 22
    • 0035797908 scopus 로고    scopus 로고
    • Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency
    • Yan, M., Brady, J. R., Chan, B. et al. 2001. Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency. Curr. Biol. 11:1547.
    • (2001) Curr. Biol. , vol.11 , pp. 1547
    • Yan, M.1    Brady, J.R.2    Chan, B.3
  • 23
    • 17944375043 scopus 로고    scopus 로고
    • TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. Impaired B cell maturation in mice lacking BLyS
    • Gross, J. A., Dillon, S. R., Mudri, S. et al. 2001. TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. Impaired B cell maturation in mice lacking BLyS. Immunity 15:289.
    • (2001) Immunity , vol.15 , pp. 289
    • Gross, J.A.1    Dillon, S.R.2    Mudri, S.3
  • 24
    • 55749115444 scopus 로고    scopus 로고
    • BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact
    • Scholz, J. L., Crowley, J. E., Tomayko, M. M. et al. 2008. BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact. Proc. Natl Acad. Sci. USA. 105:15517.
    • (2008) Proc. Natl Acad. Sci. USA. , vol.105 , pp. 15517
    • Scholz, J.L.1    Crowley, J.E.2    Tomayko, M.M.3
  • 25
    • 2942518502 scopus 로고    scopus 로고
    • Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches
    • Thien, M., Phan, T. G., Gardam, S. et al. 2004. Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches. Immunity 20:785.
    • (2004) Immunity , vol.20 , pp. 785
    • Thien, M.1    Phan, T.G.2    Gardam, S.3
  • 26
    • 0034596831 scopus 로고    scopus 로고
    • Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response
    • Do, R. K., Hatada, E., Lee, H., Tourigny, M. R., Hilbert, D. and Chen-Kiang, S. 2000. Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response. J. Exp. Med. 192:953.
    • (2000) J. Exp. Med. , vol.192 , pp. 953
    • Do, R.K.1    Hatada, E.2    Lee, H.3    Tourigny, M.R.4    Hilbert, D.5    Chen-Kiang, S.6
  • 27
    • 0036144353 scopus 로고    scopus 로고
    • Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome
    • Groom, J., Kalled, S. L., Cutler, A. H. et al. 2002. Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjogren's syndrome. J. Clin. Invest. 109:59.
    • (2002) J. Clin. Invest. , vol.109 , pp. 59
    • Groom, J.1    Kalled, S.L.2    Cutler, A.H.3
  • 28
    • 0033428703 scopus 로고    scopus 로고
    • Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
    • Mackay, F., Woodcock, S. A., Lawton, P. et al. 1999. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J. Exp. Med. 190:1697.
    • (1999) J. Exp. Med. , vol.190 , pp. 1697
    • Mackay, F.1    Woodcock, S.A.2    Lawton, P.3
  • 29
    • 0034972257 scopus 로고    scopus 로고
    • Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases
    • Cheema, G. S., Roschke, V., Hilbert, D. M. and Stohl, W. 2001. Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases. Arthritis Rheum. 44:1313.
    • (2001) Arthritis Rheum , vol.44 , pp. 1313
    • Cheema, G.S.1    Roschke, V.2    Hilbert, D.M.3    Stohl, W.4
  • 30
    • 31044440282 scopus 로고    scopus 로고
    • Elevated serum BAFF levels in patients with systemic sclerosis: enhanced BAFF signaling in systemic sclerosis B lymphocytes
    • Matsushita, T., Hasegawa, M., Yanaba, K., Kodera, M., Takehara, K. and Sato, S. 2006. Elevated serum BAFF levels in patients with systemic sclerosis: enhanced BAFF signaling in systemic sclerosis B lymphocytes. Arthritis Rheum. 54:192.
    • (2006) Arthritis Rheum , vol.54 , pp. 192
    • Matsushita, T.1    Hasegawa, M.2    Yanaba, K.3    Kodera, M.4    Takehara, K.5    Sato, S.6
  • 31
    • 17344380531 scopus 로고    scopus 로고
    • TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
    • Gross, J. A., Johnston, J., Mudri, S. et al. 2000. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature 404:995.
    • (2000) Nature , vol.404 , pp. 995
    • Gross, J.A.1    Johnston, J.2    Mudri, S.3
  • 32
    • 8444223507 scopus 로고    scopus 로고
    • Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus
    • Anolik, J. H., Barnard, J., Cappione, A. et al. 2004. Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus. Arthritis Rheum. 50:3580.
    • (2004) Arthritis Rheum , vol.50 , pp. 3580
    • Anolik, J.H.1    Barnard, J.2    Cappione, A.3
  • 33
    • 4043179907 scopus 로고    scopus 로고
    • B cell depletion as a novel treatment for systemic lupus erythematosus: a phase I/II dose-escalation trial of rituximab
    • Looney, R. J., Anolik, J. H., Campbell, D. et al. 2004. B cell depletion as a novel treatment for systemic lupus erythematosus: a phase I/II dose-escalation trial of rituximab. Arthritis Rheum. 50:2580.
    • (2004) Arthritis Rheum , vol.50 , pp. 2580
    • Looney, R.J.1    Anolik, J.H.2    Campbell, D.3
  • 34
    • 33748788266 scopus 로고    scopus 로고
    • B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis
    • Hasegawa, M., Hamaguchi, Y., Yanaba, K. et al. 2006. B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis. Am. J. Pathol. 169:954.
    • (2006) Am. J. Pathol. , vol.169 , pp. 954
    • Hasegawa, M.1    Hamaguchi, Y.2    Yanaba, K.3
  • 36
    • 57749209115 scopus 로고    scopus 로고
    • Anti-CD20 treatment prolongs syngeneic islet graft survival and delays the onset of recurrent autoimmune diabetes
    • Hu, C., Deng, S., Wong, F. S. and Wen, L. 2008. Anti-CD20 treatment prolongs syngeneic islet graft survival and delays the onset of recurrent autoimmune diabetes. Ann. N. Y. Acad. Sci. 1150:217.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1150 , pp. 217
    • Hu, C.1    Deng, S.2    Wong, F.S.3    Wen, L.4
  • 37
    • 0842278644 scopus 로고    scopus 로고
    • Severely-impaired B lymphocyte proliferation, survival and induction of the c-Myc:Cullin 1 ubiquitin ligase pathway resulting from CD22 deficiency on the C57BL/6 genetic background
    • Poe, J. C., Haas, K. M., Uchida, J., Lee, Y., Fujimoto, M. and Tedder, T. F. 2004. Severely-impaired B lymphocyte proliferation, survival and induction of the c-Myc:Cullin 1 ubiquitin ligase pathway resulting from CD22 deficiency on the C57BL/6 genetic background. J. Immunol. 172:2100.
    • (2004) J. Immunol. , vol.172 , pp. 2100
    • Poe, J.C.1    Haas, K.M.2    Uchida, J.3    Lee, Y.4    Fujimoto, M.5    Tedder, T.F.6
  • 38
    • 0029924630 scopus 로고    scopus 로고
    • Frequent aberrant immunoglobulin gene rearrangements in pro-B cells revealed by a bcl-xL transgene
    • Fang, W., Mueller, D. L., Pennell, C. A. et al. 1996. Frequent aberrant immunoglobulin gene rearrangements in pro-B cells revealed by a bcl-xL transgene. Immunity 4:291.
    • (1996) Immunity , vol.4 , pp. 291
    • Fang, W.1    Mueller, D.L.2    Pennell, C.A.3
  • 39
    • 71849093408 scopus 로고    scopus 로고
    • In vivo BLyS/BAFF neutralization ameliorates islet-directed autoimmunity in nonobese diabetic mice
    • Zekavat, G., Rostami, S. Y., Badkerhanian, A. et al. 2008. In vivo BLyS/BAFF neutralization ameliorates islet-directed autoimmunity in nonobese diabetic mice. J. Immunol. 181:8133.
    • (2008) J. Immunol. , vol.181 , pp. 8133
    • Zekavat, G.1    Rostami, S.Y.2    Badkerhanian, A.3
  • 40
    • 0346728609 scopus 로고    scopus 로고
    • Mouse CD20 expression and function
    • Uchida, J., Lee, Y., Hasegawa, M. et al. 2004. Mouse CD20 expression and function. Int. Immunol. 16:119.
    • (2004) Int. Immunol. , vol.16 , pp. 119
    • Uchida, J.1    Lee, Y.2    Hasegawa, M.3
  • 41
    • 0042697684 scopus 로고    scopus 로고
    • Enforced bcl-xL gene expression restored splenic B lymphocyte development in BAFF-R mutant mice
    • Amanna, I. J., Dingwall, J. P. and Hayes, C. E. 2003. Enforced bcl-xL gene expression restored splenic B lymphocyte development in BAFF-R mutant mice. J. Immunol. 170:4593.
    • (2003) J. Immunol. , vol.170 , pp. 4593
    • Amanna, I.J.1    Dingwall, J.P.2    Hayes, C.E.3
  • 42
    • 3042592452 scopus 로고    scopus 로고
    • The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy
    • Uchida, J., Hamaguchi, Y., Oliver, J. A. et al. 2004. The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy. J. Exp. Med. 199:1659.
    • (2004) J. Exp. Med. , vol.199 , pp. 1659
    • Uchida, J.1    Hamaguchi, Y.2    Oliver, J.A.3
  • 43
    • 0347285357 scopus 로고    scopus 로고
    • BCMA is essential for the survival of long-lived bone marrow plasma cells
    • O'Connor, B. P., Raman, V. S., Erickson, L. D. et al. 2004. BCMA is essential for the survival of long-lived bone marrow plasma cells. J. Exp. Med. 199:91.
    • (2004) J. Exp. Med. , vol.199 , pp. 91
    • O'Connor, B.P.1    Raman, V.S.2    Erickson, L.D.3
  • 44
    • 0037097665 scopus 로고    scopus 로고
    • Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators
    • Hsu, B. L., Harless, S. M., Lindsley, R. C., Hilbert, D. M. and Cancro, M. P. 2002. Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators. J. Immunol. 168:5993.
    • (2002) J. Immunol. , vol.168 , pp. 5993
    • Hsu, B.L.1    Harless, S.M.2    Lindsley, R.C.3    Hilbert, D.M.4    Cancro, M.P.5
  • 45
    • 8444222647 scopus 로고    scopus 로고
    • B cells expressing Bcl-2 and a signaling-impaired BAFF-specific receptor fail to mature and are deficient in the formation of lymphoid follicles and germinal centers
    • Rahman, Z. S. and Manser, T. 2004. B cells expressing Bcl-2 and a signaling-impaired BAFF-specific receptor fail to mature and are deficient in the formation of lymphoid follicles and germinal centers. J. Immunol. 173:6179.
    • (2004) J. Immunol. , vol.173 , pp. 6179
    • Rahman, Z.S.1    Manser, T.2
  • 46
    • 4043075603 scopus 로고    scopus 로고
    • TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology
    • Sasaki, Y., Casola, S., Kutok, J. L., Rajewsky, K. and Schmidt-Supprian, M. 2004. TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology. J. Immunol. 173:2245.
    • (2004) J. Immunol. , vol.173 , pp. 2245
    • Sasaki, Y.1    Casola, S.2    Kutok, J.L.3    Rajewsky, K.4    Schmidt-Supprian, M.5
  • 47
    • 33745485499 scopus 로고    scopus 로고
    • ST6Gal-I restrains CD22-dependent antigen receptor endocytosis and Shp-1 recruitment in normal and pathogenic immune signaling
    • Grewal, P. K., Boton, M., Ramirez, K. et al. 2006. ST6Gal-I restrains CD22-dependent antigen receptor endocytosis and Shp-1 recruitment in normal and pathogenic immune signaling. Mol. Cell. Biol. 26:4970.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 4970
    • Grewal, P.K.1    Boton, M.2    Ramirez, K.3
  • 48
    • 0035803468 scopus 로고    scopus 로고
    • Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen
    • Schneider, P., Takatsuka, H., Wilson, A. et al. 2001. Maturation of marginal zone and follicular B cells requires B cell activating factor of the tumor necrosis factor family and is independent of B cell maturation antigen. J. Exp. Med. 194:1691.
    • (2001) J. Exp. Med. , vol.194 , pp. 1691
    • Schneider, P.1    Takatsuka, H.2    Wilson, A.3
  • 49
    • 0034525374 scopus 로고    scopus 로고
    • The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability
    • Harris, M. H. and Thompson, C. B. 2000. The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability. Cell Death Differ. 7:1182.
    • (2000) Cell Death Differ , vol.7 , pp. 1182
    • Harris, M.H.1    Thompson, C.B.2
  • 50
    • 33644914684 scopus 로고    scopus 로고
    • Circulating levels of B lymphocyte stimulator in patients with rheumatoid arthritis following rituximab treatment: relationships with B cell depletion, circulating antibodies, and clinical relapse
    • Cambridge, G., Stohl, W., Leandro, M. J., Migone, T. S., Hilbert, D. M. and Edwards, J. C. 2006. Circulating levels of B lymphocyte stimulator in patients with rheumatoid arthritis following rituximab treatment: relationships with B cell depletion, circulating antibodies, and clinical relapse. Arthritis Rheum. 54:723.
    • (2006) Arthritis Rheum , vol.54 , pp. 723
    • Cambridge, G.1    Stohl, W.2    Leandro, M.J.3    Migone, T.S.4    Hilbert, D.M.5    Edwards, J.C.6
  • 51
    • 34247613820 scopus 로고    scopus 로고
    • Increase of B cell-activating factor of the TNF family (BAFF) after rituximab treatment: insights into a new regulating system of BAFF production
    • Lavie, F., Miceli-Richard, C., Ittah, M., Sellam, J., Gottenberg, J. E. and Mariette, X. 2007. Increase of B cell-activating factor of the TNF family (BAFF) after rituximab treatment: insights into a new regulating system of BAFF production. Ann. Rheum. Dis. 66:700.
    • (2007) Ann. Rheum. Dis. , vol.66 , pp. 700
    • Lavie, F.1    Miceli-Richard, C.2    Ittah, M.3    Sellam, J.4    Gottenberg, J.E.5    Mariette, X.6
  • 52
    • 34247574625 scopus 로고    scopus 로고
    • B cells and the BAFF/ APRIL axis: fast-forward on autoimmunity and signaling
    • Mackay, F., Silveira, P. A. and Brink, R. 2007. B cells and the BAFF/ APRIL axis: fast-forward on autoimmunity and signaling. Curr. Opin. Immunol. 19:327.
    • (2007) Curr. Opin. Immunol. , vol.19 , pp. 327
    • Mackay, F.1    Silveira, P.A.2    Brink, R.3


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