Competition for BLyS-mediated signaling through Bcmd/BR3 regulates peripheral B lymphocyte numbers

Current Biology

Volumn 11, Issue 24, 2001, Pages 1986-1989

  Harless, Susan M ^a   Lentz, Vicky M ^a   Sah, Alex P ^a   Hsu, Benjamin L ^a   Clise Dwyer, Karen ^b   Hilbert, David M ^c   Hayes, Colleen E ^b   Cancro, Michael P ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0035846593     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00598-X     Document Type: Article

References (39)

1. Migration and lifespan of lymphocytes
2. Proliferation kinetics and the lifespan of B cells in central and peripheral lymphoid organs
3. Peripheral B cell maturation. II. Heat-stable antigen(hi) splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells
4. Evidence for the clonal abortion theory of B-lymphocyte tolerance
5. In vitro tolerance induction of bone marrow cells: A marker for B cell maturation
6. Transgenic mice and analysis of B-cell tolerance
7. Reduced life span of anergic self-reactive B cells in a double-transgenic model
8. Revising B cell receptors
9. A B-cell receptor-specific selection step governs immature to mature B cell differentiation
10. Most peripheral B cells in mice are ligand selected
11. Aberrant B cell development and immune response in mice with a compromised BCR complex
12. BLyS: Member of the tumor necrosis factor family and B lymphocyte stimulator
13. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
14. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth
15. Identification and characterization of a novel cytokine, THANK, a TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase
16. Severe B cell hyperplasia and autoimmune disease in TALL 1 transgenic mice
17. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
18. BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population
19. The BCMA gene, preferentially expressed during B lymphoid maturation, is bidirectionally transcribed
20. BCMAp: An integral membrane protein in the Golgi apparatus of human mature B lymphocytes
21. The characterization of murine BCMA gene defines it as a new member of the tumor necrosis factor receptor superfamily
22. NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily
23. Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency
24. Phenotypeic and genetic characterization of a unique B lymphocyte deficiency in strain A/WySnJ mice
25. A single autosomal gene defect severely limits IgG but not IgM responses in B lymphocyte-deficient A/WySnJ mice
26. Bcmd governs recruitment of new B cells into the stable peripheral B cell pool in the A/WySnJ mouse
27. Bcmd decreases the life span of B-2 but not B-1 cells in A/WySnJ mice
28. An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway
29. BAFF-R, a novel TNF receptor that specifically interacts with BAFF
30. BAFF mediates survival of peripheral immature B lymphocytes
31. Mutations affecting either generation or survival of cells influence the pool size of mature B cells
32. Circulating T and B lymphocytes of the mouse. II. Lifespan
33. The turnover of B cell populations
34. Enforced Bcl-2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease
35. Long-lived S cells are distinguished by elevated expression of A1
36. Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response
37. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
38. Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire