An artificial metalloenzyme: Creation of a designed copper binding site in a thermostable protein

Angewandte Chemie - International Edition

Volumn 49, Issue 30, 2010, Pages 5151-5155

  Podtetenieff, John ^a   Taglieber, Andreas ^a   Bill, Eckhard ^b   Reijerse, Edward J ^b   Reetz, Manfred T ^a  

^a MAX PLANCK INSTITUT FÜR KOHLENFORSCHUNG   (Germany)

^b MAX PLANCK INSTITUTE FOR CHEMICAL ENERGY CONVERSION   (Germany)

Author keywords

Copper; Diels Alder reaction; Enantioselectivity; Heterogeneous catalysis; Metalloenzymes

Indexed keywords

COPPER BINDING SITE; DIELS-ALDER REACTION; ENANTIOSELECTIVE DIELS-ALDER REACTIONS; HETEROGENEOUS CATALYSIS; METALLOENZYMES; SITE-SPECIFIC MUTAGENESIS;

BINDING ENERGY; COPPER; ELECTRON TRANSITIONS; ENANTIOSELECTIVITY; ENZYMES;

CATALYSIS;

COPPER; HYDROLASE; IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE;

ARTICLE; BINDING SITE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME STABILITY; ENZYMOLOGY; METABOLISM; PROTEIN TERTIARY STRUCTURE; TEMPERATURE; THERMOTOGA MARITIMA;

AMINOHYDROLASES; BINDING SITES; CATALYSIS; COPPER; ENZYME STABILITY; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; TEMPERATURE; THERMOTOGA MARITIMA;

EID: 77954835199     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201002106     Document Type: Article

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