Structural evidence for ammonia tunneling across the (βα)8 barrel of the imidazole glycerol phosphate synthase bienzyme complex

Structure

Volumn 10, Issue 2, 2002, Pages 185-193

  Douangamath, Alice ^a   Walker, Martina ^a   Beismann Driemeyer, Silke ^b   Vega Fernandez, M Cristina ^a   Sterner, Reinhard ^b   Wilmanns, Matthias ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

( )8 barrel; Ammonia tunnel; Bienzyme complex; Glutamine amidotransferase; Imidazole glycerol phosphate synthase; X ray structure

Indexed keywords

AMMONIA; GLUTAMINASE; HISTIDINE; IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE; TRANSFERASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BIOSYNTHESIS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME SUBUNIT; METABOLISM; NONHUMAN; PRIORITY JOURNAL; THERMOPHILIC BACTERIUM; THERMOTOGA MARITIMA; X RAY;

AMINO ACID SEQUENCE; AMINOHYDROLASES; AMMONIA; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; HYDROGEN BONDING; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SUBUNITS; STRUCTURE-ACTIVITY RELATIONSHIP; THERMOTOGA MARITIMA;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; THERMOTOGA; THERMOTOGA MARITIMA;

EID: 0036175240     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(02)00702-5     Document Type: Article

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