Design and synthesis of low molecular weight compounds with complement inhibition activity

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 16, 2005, Pages 4891-4899

  Master, Hoshang E ^a   Khan, Shabana I ^b   Poojari, Krishna A ^a  

^a ST XAVIER S COLLEGE   (India)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Bioisosteres; Carbonyl compounds; Carboxylic acid; Classical pathway; Complement inhibitors; Hemolysis; Non cytotoxic; Tetrazoles; trans Phenyl acrylic acid

Indexed keywords

ACRYLIC ACID DERIVATIVE; CARBONYL DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; TETRAZOLE DERIVATIVE;

ANIMAL CELL; ARTICLE; COMPLEMENT INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; MOLECULAR WEIGHT; NONHUMAN; PHARMACOPHORE;

ACRYLATES; ANIMALS; CARBOXYLIC ACIDS; CELL LINE; COMPLEMENT INACTIVATOR PROTEINS; COMPLEMENT PATHWAY, CLASSICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ESTERS; ETHERS; KIDNEY; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR WEIGHT; TETRAZOLES;

EID: 21744456872     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.04.075     Document Type: Article

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