Acyl-CoA synthetase as a cancer survival factor: Its inhibition enhances the efficacy of etoposide

Cancer Science

Volumn 100, Issue 8, 2009, Pages 1556-1562

  Mashima, Tetsuo ^a   Sato, Shigeo ^b   Okabe, Sachiko ^a   Miyata, Satoshi ^a   Matsuura, Masaaki ^a   Sugimoto, Yoshikazu ^c,d   Tsuruo, Takashi ^d   Seimiya, Hiroyuki ^a  

^a CANCER INSTITUTE   (Japan)

^b Experimental Chemotherapy   (Japan)

^c KEIO UNIVERSITY   (Japan)

^d CANCER CHEMOTHERAPY CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CYTOCHROME C; ETOPOSIDE; LIGASE; LONG CHAIN FATTY ACID COENZYME A LIGASE; LONG CHAIN FATTY ACID COENZYME A LIGASE L5; PROTEIN BAX; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER SURVIVAL; CELL DEATH; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME RELEASE; GENE OVEREXPRESSION; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; LOW DRUG DOSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BENZIMIDAZOLES; CASPASES; CATALYSIS; CELL LINE, TUMOR; CELL SURVIVAL; COENZYME A LIGASES; CYTOCHROME C GROUP; DOSE-RESPONSE RELATIONSHIP, DRUG; ETOPOSIDE; FLUORESCENT ANTIBODY TECHNIQUE; FLUORESCENT DYES; GLIOMA; HUMANS; INDOLES; INJECTIONS, SUBCUTANEOUS; ISOENZYMES; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; SUBCELLULAR FRACTIONS; TETRAZOLIUM SALTS; THIAZOLES; TRIAZENES; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 67650689624     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2009.01203.x     Document Type: Article

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