Long-chain fatty acids induce lipid droplet formation in a cultured human hepatocyte in a manner dependent of acyl-CoA synthetase

Biological and Pharmaceutical Bulletin

Volumn 29, Issue 11, 2006, Pages 2174-2180

  Fujimoto, Yasuyuki ^a   Onoduka, Jun ^a   Homma, Koichi J ^a   Yamaguchi, Shinji ^a   Mori, Masahiro ^a   Higashi, Yusuke ^b   Makita, Minoru ^a   Kinoshita, Tetsuaki ^a   Noda, Jun Ichi ^a   Itabe, Hiroyuki ^c   Takano, Tatsuya ^a  

^a TEIKYO UNIVERSITY   (Japan)

^b Tulane Center for Cardiovascular Health   (United States)

^c SHOWA UNIVERSITY   (Japan)

Author keywords

Fatty acid; Hepatocyte; Lipid droplet; Neutral lipid; Triacsin c

Indexed keywords

ENZYME INHIBITOR; FAT DROPLET; GLUCOSE; INSULIN; LITHIUM; LONG CHAIN FATTY ACID; LONG CHAIN FATTY ACID COENZYME A LIGASE; OLEIC ACID; PREGNENOLONE; TRIACSIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CELL FRACTIONATION; CELL TRANSPORT; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVATION; FATTY LIVER; HUMAN; HUMAN CELL; LIPID ANALYSIS; LIPID STORAGE; LIPOGENESIS; LIVER CELL;

CAFFEINE; CELL LINE; CHROMATOGRAPHY, THIN LAYER; COENZYME A LIGASES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; FATTY ACIDS; GLUCOSE; HEPATOCYTES; HUMANS; IMMUNOBLOTTING; INSULIN; ISOPROTERENOL; LIPID METABOLISM; MEMBRANE PROTEINS; PREGNENOLONE; QUATERNARY AMMONIUM COMPOUNDS; SUBCELLULAR FRACTIONS; TIME FACTORS; TRIAZENES; TRIGLYCERIDES;

EID: 33750615668     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.29.2174     Document Type: Article

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