The endogenous cannabinoid anandamide inhibits transient receptor potential vanilloid type 1 receptor-mediated currents in rat cultured primary sensory neurons

Acta Physiologica Hungarica

Volumn 97, Issue 2, 2010, Pages 149-158

  Santha P ^a,b   Jenes, A ^a,c   Somogyi, Cs ^a   Nagy, Istvan ^a  

^a CHELSEA AND WESTMINSTER HOSPITAL   (United Kingdom)

^b UNIVERSITY OF SZEGED   (Hungary)

^c UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

anandamide; capsaicin; heat hyperalgesia; inflammation; nociception; pain; PKA; TRPV1; vanilloid

Indexed keywords

ANANDAMIDE; CANNABINOID 1 RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; VANILLOID RECEPTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DESENSITIZATION; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; HYPERALGESIA; INTRACELLULAR SIGNALING; MEMBRANE CURRENT; NERVE CELL CULTURE; NOCICEPTIVE RECEPTOR; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR SENSITIVITY; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SPINAL GANGLION; WHOLE CELL;

ANIMALS; ARACHIDONIC ACIDS; CAPSAICIN; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENDOCANNABINOIDS; EVOKED POTENTIALS; FEMALE; GANGLIA, SPINAL; ISOQUINOLINES; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION; POLYUNSATURATED ALKAMIDES; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, CANNABINOID, CB1; SENSORY RECEPTOR CELLS; SENSORY SYSTEM AGENTS; SULFONAMIDES; TRPV CATION CHANNELS;

EID: 77954522667     PISSN: 0231424X     EISSN: 15882683     Source Type: Journal    
DOI: 10.1556/APhysiol.97.2010.2.1     Document Type: Article

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