The effect of metal imbalances on scrapie neurodegeneration

Zoonoses and Public Health

Volumn 57, Issue 5, 2010, Pages 358-366

  Hortells, P ^a   Monleon E ^a   Acin C ^a   Vargas, A ^a   Vasseur, V ^b   Salomon, A ^c   Ryffel, B ^b   Cesbron, J Y ^c   Badiola, J J ^a   Monzon M ^a  

^a UNIVERSITY OF ZARAGOZA   (Spain)

^b UNIVERSITÉ D'ORLÉANS   (France)

^c Institut Jean Roget   (France)

Author keywords

copper; manganese; neuropathological lesions; prion; transgenic mice

Indexed keywords

COPPER; MANGANESE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN SPONGIOSIS; CONTROLLED STUDY; DIET; DIET SUPPLEMENTATION; DISEASE COURSE; DISEASE PREDISPOSITION; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE CELL; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; SCRAPIE;

EID: 77954515332     PISSN: 18631959     EISSN: 18632378     Source Type: Journal    
DOI: 10.1111/j.1863-2378.2009.01230.x     Document Type: Article

References (35)

1. Barr, J. B., R. A. Somerville, Y. L. Chung J. R. Fraser, 2004 : Microdissection: a method developed to investigate mechanisms involved in transmissible spongiform encephalopathy pathogenesis. BMC Infect. Dis. 4, 1 9.
2. Brown, D. R., 2001 : Copper and prion diseases. Brain Res. Bull. 55, 165 173.
3. Brown, D. R., F. Afiz, L. L. Glasssmith, B. S. Wong, I. M. Jones, C. Clive S. J. Haswell, 2000 : Consequences of manganese replacement of copper for prion protein function and proteinase resistance. EMBO J. 19, 1180 1196.
4. Bueler, H., A. Aguzzi, A. Sailer, R. A. Greiner, P. Autenried, M. Aguet C. Weissmann, 1993 : Mice devoid of PrP are resistant to scrapie. Cell 73, 1339 1347.
5. Bush, A. I., 2000 : Metals and neuroscience. Curr. Opin. Chem. Biol. 4, 184 191.
6. Campbell, A., M. A. Smith, L. M. Sayre, S. C. Bondy G. Perry, 2001 : Mechanisms by which metals promote events connected to neurodegenerative diseases. Brain Res. Bull. 55, 125 132.
7. Cerpa, W., L. Varela-Nallar, A. E. Reyes, A. N. Minniti N. C. Inestrosa, 2005 : Is there a role for copper in neurodegenerative diseases? Mol. Aspects Med. 26, 405 420.
8. Chihota, C. M., M. B. Gravenor M. Baylis, 2004 : Investigation of trace elements in soil as risk factors in the epidemiology of Scrapie. Vet. Rec. 154, 809 813.
9. Choi, C. J., A. Kanthasamy, V. Anantharam A. G. Kanthasamy, 2006 : Interaction of metals with prion protein: Possible role of divalent cations in the pathogenesis of prion diseases. Neurotoxicology 27, 777 787.
10. Esposito, L., J. Raber, L. Kekonius, F. Yan, G. Q. Yu, N. Bien-Ly, J. Puoliväli, K. Scearce-Levie, E. Masliah L. Mucke, 2006 : Reduction in mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice. J. Neurosci. 26, 5167 5179.
11. Fischer, M., T. Rulicke, A. Raeber, A. Sailer, M. Moser, B. Oesch, S. Brandner, A. Aguzzi C. Weissmann, 1996 : Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. EMBO J. 15, 1255 1264.
12. Fraser, H. A. G. Dickinson, 1968 : The sequential development of the brain lesions of Scrapie in three strains of mice. J. Comp. Pathol. 78, 301 311.
13. Gaeta, A. R. C. Hider, 2005 : The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy. Br. J. Pharmacol. 146, 1041 1059.
14. Giese, A., J. Levin H. Kretzschmar, 2004 : Effect of metal ions on the novo aggregation of full-length prion protein. Biochem. Biophys. Res. Commun. 320, 1240 1246.
15. Hijazi, N., Y. Shaked, H. Rosenmann, T. Ben-Hur R. Gabizon, 2003 : Copper binding to PrPc may inhibit prion disease propagation. Brain Res. 993, 192 200.
16. Horning, M. S., L. J. Blakemore P. Q. Trombley, 2000 : Endogenous mechanisms of neuroprotection: role of zinc, copper, and carnosine. Brain Res. 852, 56 61.
17. Jóhannesson, T., K. B. Gudmundsdóttir, T. Eiríksson, J. Kristinsson S. Sigurdarson, 2004 : Copper and manganese in hay samples from Scrapie-free, Scrapie-prone and Scrapie-afflicted farms in Iceland. Icel. Agr. Sci. 16-17, 45 52.
18. Kim, N. H., J. K. Choi, B. H. Jeong, J. I. Kim, M. S. Kwon, R. I. Carp Y. S. Kim, 2005 : Effect of transition metals (Mn, Cu, Fe) and deoxycholic acid on the conversion of PrPc to PrPsc. FASEB J. 19, 783 785.
19. Lehmann, S., 2002 : Metal ions and prion diseases. Curr. Opin. Chem. Biol. 6, 187 192.
20. Levin, J., U. Bertsch, H. Kretzschmar A. Giese, 2005 : Single particle analysis of manganese-induced prion protein aggregates. Biochem. Biophys. Res. Commun. 329, 1200 1207.
21. Lewis, R. J. D. V. Sweet (eds 1984 : Registry of Toxic Effects of Chemical Substances, Vol 1. US Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health
22. McKenzie, D., J. Bartz, J. Mirwald, D. Olander, R. Marsh J. Aiken, 1998 : Reversibility of Scrapie inactivaton is enhanced by copper. J. Biol. Chem. 273, 25545 25547.
23. Monleón, E., M. Monzón, P. Hortells, A. Vargas, C. Acín J. J. Badiola, 2004 : Detection of PrPsc on lymphoid tissues from naturally affected Scrapie animals: comparison of three visualization systems. J. Histochem. Cytochem. 51, 15 18.
24. Pattison, I. H. J. N. Jebbet, 1971a : Histopathological similarities between Scrapie and cuprizone toxicity in mice. Nature 230, 115.
25. Pattison, I. H. J. N. Jebbet, 1971b : Clinical and histological observations between cuprizone toxicity and Scrapie in mice. Res. Vet. Sci. 12, 378 380.
26. Petersen, R. B., S. L. Siedlak, H. G. Lee, Y. S. Kim, A. Nunomura, F. Tagliavini, B. Ghetti, P. Cras, P. I. Moreira, R. J. Castellani, M. Guentchev, H. Budka, J. W. Ironside, P. Gambetti, M. A. Smith G. Perry, 2005 : Redox metals and oxidative abnormalities in human prion diseases. Acta Neuropathol. 110, 232 238.
27. Purdey, M., 2000 : Ecosystems supporting clusters of sporadic TSEs demonstrate excesses of the radical generating divalent cation manganese and deficiencies of antioxidant co-factors; Cu, Se, Fe, Zn. Does a foreign cation substitution at PrP's Cu domain initiate TSE? Med. Hypotheses 54, 278 306.
28. Quaglio, E., R. Chiesa D. A. Harris, 2001 : Copper converts the cellular prion protein into a protease-resistant species that is distict from the Scrapie isoform. J. Biol. Chem. 14, 11432 11438.
29. Rachidi, W., J. Riondel, H. M. McMahon A. Favier, 2005 : La protéine du prion et le cuivre: un lien mystérieux. Pathol. Biol. 53, 244 250.
30. Rodrigo, J., J. A. Pedrosa, M. A. Peinado, F. J. Esteban, A. P. Fernández, M. L. Bentura, J. Martínez de Velasco R. Martínez-Murillo, 1996 : Fijadores más usuales empleados en inmunocitoquímica. In : Peinado, M. A., J. A. Pedrosa J. Rodrigo (eds Avances en inmunocitoquímica y técnicas relacionadas, pp. 63 79. Universidad de Jaén
31. Sigurdsson, E. M., D. R. Brown, M. A. Alim, H. Scholtzova, R. Carp, H. C. Meeker, F. Prelli, B. Frangione T. Wisniewski, 2003 : Copper chelation delays the onset of prion diseases. J. Biol. Chem. 278, 46199 46202.
32. Thackray, A. M., R. Knight, S. J. Haswell, R. Bujdoso D. R. Brown, 2002 : Metal imbalance and compromised antioxidant function are early changes in prion disease. Biochem. J. 362, 253 258.
33. Tsiroulnikov, K., J. M. Chobert T. Haertlé, 2006 : Copper-dependent degradation of recombinant ovine prion protein. Phosphatidylinositol stimulates aggregation and copper-driven disappearance of prion protein. FEBS J. 273, 1959 1965.
34. Waggoner, D. J., T. B. Bartnikas D. Gitlin, 1999 : The role of copper in neurodegenerative diseases. Neurobiol. Dis. 6, 221 230.
35. Zucconi, G. G., S. Cipriani, R. Scattoni, I. Balgkouranidou, D. P. Hawkinst K. V. Ragnarsdottirt, 2007 : Copper deficiency elicits glial and neuronal response typical of neurodegenerative disorders. Neuropathol. Appl. Neurobiol. 33, 212 225.